Publication:
Cytotoxicity of Different Nano Composite Resins on Human Gingival and Periodontal Ligament Fibroblast Cell Lines: An In Vitro Study

Simple item page
dc.contributor.authorYILMAZ GÖLER, AYŞE MİNE
dc.contributor.authorsKavuncu, Gamze; Yilmaz, Ayse Mine; Yilmaz, Betul Karademir; Atali, Pinar Yilmaz; Altunok, Elif Cigdem; Kuru, Leyla; Agrali, Omer Birkan
dc.date.accessioned2022-03-14T10:53:35Z
dc.date.available2022-03-14T10:53:35Z
dc.date.issued2020-03-01
dc.description.abstractThe aim of this study is to determine the cytotoxicity of three different nano composite resins (CRs) on human gingival fibroblast (hGF) and periodontal ligament fibroblast (hPDLF) cell lines. These CRs selected were nanohybrid organic monomer-based Admira Fusion (AF), nanohybrid Bis-(acryloyloxymethyl) tricyclo [5.2.1.0.sup.2,6] decane-based Charisma Topaz (CT), and supra nano filled resin-based Estelite Quick Sigma (EQS). MTT assay was performed to assess the cytotoxicity of CRs at 24 h and one week. AF and EQS applied on hGF cells at 24 h and one week demonstrated similar cytotoxic outcomes. Cytotoxicity of CT on hGF cells at one week was higher than 24 h (p = 0.04). Cytotoxicity of CT on hGF cells was higher at 24 h (p = 0.002) and one week (p = 0.009) compared to control. All composites showed higher cytotoxicity on hPDLF cells at one week than the 24 h (AF; p = 0.02, CT; p = 0.02, EQS; p = 0.04). AF and EQS demonstrated lower cytotoxicity on hPDLF cells than the control group at 24 h (AF; p = 0.01, EQS; p = 0.001). CT was found more cytotoxic on hPDLF cells than the control (p = 0.01) and EQS group (p = 0.008) at one week. The cytotoxicity of CRs on hGF and hPDLF cells vary, according to the type of composites, cell types, and exposure time.
dc.identifier.doi10.3390/biomedicines8030048
dc.identifier.eissn2227-9059
dc.identifier.pubmed32121617
dc.identifier.urihttps://hdl.handle.net/11424/245340
dc.identifier.wosWOS:000530205700007
dc.language.isoeng
dc.publisherMDPI
dc.relation.ispartofBIOMEDICINES
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectbiocompatibility
dc.subjectcell culture
dc.subjectcomposite resin
dc.subjectcytotoxicity
dc.subjectfibroblasts
dc.subjectDENTAL MATERIALS
dc.subjectRESTORATIVE MATERIALS
dc.subjectGLASS-IONOMER
dc.subjectTISSUE
dc.subjectTOXICITY
dc.subjectMONOMERS
dc.subjectCOMPONENTS
dc.subjectCOVERAGE
dc.subjectCULTURE
dc.subjectMODELS
dc.titleCytotoxicity of Different Nano Composite Resins on Human Gingival and Periodontal Ligament Fibroblast Cell Lines: An In Vitro Study
dc.typearticle
dspace.entity.typePublication
local.avesis.idb3bfffb1-7bcb-444a-9e8b-69f42cbf023a
local.import.packageSS16
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.articlenumber48
local.journal.numberofpages13
local.journal.quartileQ1
oaire.citation.issue3
oaire.citation.titleBIOMEDICINES
oaire.citation.volume8
relation.isAuthorOfPublication8a72311b-9078-47c0-9fd8-bd73292b7739
relation.isAuthorOfPublication.latestForDiscovery8a72311b-9078-47c0-9fd8-bd73292b7739

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Kavuncu et al. - 2020 - Cytotoxicity of Different Nano Composite Resins on.pdf
Size:
899.24 KB
Format:
Adobe Portable Document Format
Download

Collections

Research Outputs