Publication: Ga-68-Prostate-Specific Membrane Antigen PET-Positive Paget Bone Disease With Metastatic Prostatic Carcinoma
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Date
2020
Authors
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LIPPINCOTT WILLIAMS & WILKINS
Abstract
Paget bone disease is a chronic benign bone disease characterized by excessive and abnormal bone remodeling. The scintigraphic and bone SPECT/CT hybrid imaging appearances of the affected bone(s) depend on the stage of the disease. We report the case of a patient newly diagnosed with prostate cancer who was found to have multiple osseous metastases, with coexisting Paget disease in the left hemipelvis diagnosed because of typical scintigraphic and SPECT/CT appearance.Ga-68-prostate-specific membrane antigen PET/CT was also performed for initial staging. Pagetoid bones showed increased prostate-specific membrane antigen uptake like skeletal metastases.
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Keywords
Paget disease of bone, Tc-99m-methylene diphosphonate bone scintigraphy, prostate cancer, bone metastases, SPECT-CT (single photon emission computerized tomography/computed tomography), Ga-68-PSMA PET-CT, POTENTIAL-PITFALL, (68)GA-PSMA, FRACTURE, PATIENT