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Pancreatic duct cell carcinoma with positive In-111 octreotide uptake

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dc.contributor.authorsTurhal, NS; Bruckner, HW
dc.date.accessioned2022-03-12T16:59:32Z
dc.date.available2022-03-12T16:59:32Z
dc.date.issued2000
dc.description.abstractDuct cell adenocarcinomas may produce neuroendocrine markers such as pancreatic polypeptide, gastrin and gastrin releasing hormones. A 53 year old patient, with a history of insulin dependent diabetes, was found to have a pancreatic mass which was later pathologically demonstrated to be a duct cell adenocarcinoma. The tumor produced elevated circulating neuroendocrine markers specifically gastrin and pancreatic polypeptides. An In-111 Octreotide imaging showed definite uptake of Octreotide by the tumor. The patient was subsequently treated with Somatostatin analog which resulted in the reduction of some of the circulating endocrine markers. The patient had essentially six months of asymptomatic clinical remission but then she relapsed. Octreotide scanning could be useful for selected patients with pathologic diagnosis of duct cell adenocarcinoma, because some tumors may have neuroendocrine features and can be imaged, and might even respond to Somatostatin analog therapy.
dc.identifier.doidoiWOS:000088292700020
dc.identifier.issn0392-9078
dc.identifier.pubmed10965825
dc.identifier.urihttps://hdl.handle.net/11424/227206
dc.identifier.wosWOS:000088292700020
dc.language.isoeng
dc.publisherAPSIT ASSOC PROM STUD IMMUNOL TUMOR
dc.relation.ispartofJOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectpancreatic carcinoma
dc.subjectsomatostatin
dc.subjectoctreotide
dc.subject(111)indium
dc.subjectscintigraphy
dc.subjectSOMATOSTATIN ANALOG OCTREOTIDE
dc.subjectLUNG-CANCER
dc.subjectTUMORS
dc.subjectLOCALIZATION
dc.subjectEXPRESSION
dc.subjectGASTRIN
dc.subjectADENOCARCINOMA
dc.subjectGROWTH
dc.subjectCOLON
dc.titlePancreatic duct cell carcinoma with positive In-111 octreotide uptake
dc.typearticle
dspace.entity.typePublication
local.avesis.id5e7dc645-917f-4cbb-a1b8-c2d8875fb824
local.import.packageSS17
local.indexed.atWOS
local.journal.numberofpages4
oaire.citation.endPage244
oaire.citation.issue2
oaire.citation.startPage241
oaire.citation.titleJOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
oaire.citation.volume19

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