Person: ÇAM, HAYDAR KAMİL
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ÇAM
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HAYDAR KAMİL
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Publication Metadata only Radikal prostatektomi patolojisinde gleason grade grubu yükselmesinin klinik önemi var mı?(2021-11-14) ŞAHİN, BAHADIR; DÖRÜCÜ, DOĞANCAN; ÇAM, HAYDAR KAMİL; ÖZGÜR G., TOPBAŞ F. B., ŞAHİN B., DÖRÜCÜ D., TİNAY İ., ÇAM H. K.Publication Metadata only Is Cognitive MR Fusion Biopsy Superior to Standard TRUS Guided Prostate Biopsy? Our Clinical Experience(2022-06-01) FİLİNTE, DENİZ; ÇAM, HAYDAR KAMİL; ŞAHİN, BAHADIR; DÖRÜCÜ, DOĞANCAN; ŞAHİN B., DÖRÜCÜ D., TİNAY İ., FİLİNTE D., ÇAM H. K.Objective: To share our clinical experience with cognitive prostate biopsy and compare results of cognitive biopsies with standard biopsies.Publication Metadata only Accuracy of transrectal ultrasound guided prostate biopsy: Histopathological correlation to matched prostatectomy specimens(BLACKWELL PUBLISHING ASIA, 2002) ÇAM, HAYDAR KAMİL; Cam, K; Yucel, S; Turkeri, L; Akdas, ABackground: The Gleason grading system is currently the world's most commonly used histological system for prostate cancer. It provides significant information about the prognosis. Therefore, Gleason score is accepted as an important factor in therapeutic decision-making for prostate cancer. This retrospective study assessed the correlation of transrectal ultrasound (TRUS) guided biopsy and radical prostatectomy specimens in terms of Gleason scores. Methods: We reviewed the records of 103 patients who underwent radical prostatectomy due to clinically localized prostate cancer. The Gleason scores of the TRUS biopsies were compared with the respective Gleason scores of surgical specimen. Results: In 28.7% of cases, the TRUS biopsy score was the same as that of the radical prostatectomy specimen. The most significant discordance was the upgrading of well-differentiated tumors after surgery in 71.7% of cases. However, in 81.8% of cases with high Gleason score on TRUS, biopsy was correlated with poorly differentiated tumor after surgery. Conclusions: Well-differentiated tumors on TRUS biopsy did not correlate with the grades of final pathology in the majority of cases; however, a high Gleason score on TRUS biopsy usually indicated a poorly differentiated tumor on prostatectomy specimen. Therefore, the treatment algorithms for particularly well-differentiated tumors should not be deduced from biopsy histology alone.Publication Metadata only The effect of using a standard Illustrated consent form on anxiety levels in the urodynamic investigation: A prospective clinical study(2022-09-07) ŞAHİN, BAHADIR; ŞEKERCİ, ÇAĞRI AKIN; ONUR, AHMET RAHMİ; ÇAM, HAYDAR KAMİL; TARCAN, TUFAN; Özkan O., Güçtaş A. Ö. , Şahin B., Şekerci Ç. A. , Onur A. R. , Çam H. K. , Tarcan T.Publication Open Access The Efficacy of Early Mobilization after Urologic Radical Surgery(GALENOS YAYINCILIK, 2015-12-05) ÇAM, HAYDAR KAMİL; Vermisli, Sevgi; Cam, KamilContemporary evidence based trials suggest that same changes in the traditional approach for the care of patients provide a rapid recovery and return to daily life after surgery. Consequently, a decrease in the surgical complications and shorter hospital stay would be provided. These new multi-perspective approaches which are different from the classical approach are defined as fast track surgery. Early mobilization besides early extubation and rapid discharge from extensive care unit constitute the major components of fast track surgery in order to bring a shorter hospital stay. Nurses together with surgeons and anesthesiologists are all active members of the care team which may also include the patient by him or herself. The aim of this review was to discuss the efficacy of early mobilization after urologic surgeries.Publication Open Access Contemporary Trends in Adjuvant and Neoadjuvant Treatment for Renal Cell Carcinoma(GALENOS YAYINCILIK, 2018-09-01) ÇAM, HAYDAR KAMİL; Cam, KamilRenal cell carcinoma is an increasingly significant cancer in which surgical resection is still the sole curative approach. There is a risk of recurrence in one-third of patients after surgery. Successful experiences with some solid organ cancers and effective treatment response to targeted agents in metastatic cases have suggested a similar adjuvant approach for renal cell carcinoma. Consequently, placebo-controlled adjuvant trials have been reported and the Food and Drug Administration approved sunutinib as an adjuvant treatment after nephrectomy in high-risk patients, with the risk of treatment-related side effects. Several clinical series have indicated that neoadjuvant application can provide significant downsizing of the cancer mass in complex cases and enable radical surgery. Similarly, neoadjuvant therapy could enable nephron-sparing surgery for certain patients. Both adjuvant and neoadjuvant approaches for renal cell carcinoma require further trials with larger patient numbers. This review presents contemporary experience on adjuvant and neoadjuvant treatment for renal cell carcinoma.Publication Open Access The Effects of Hormonal Therapy on Quality of Life in Prostate Cancer(GALENOS YAYINCILIK, 2015-12-05) ÇAM, HAYDAR KAMİL; Senoglu, Yusuf; Cam, KamilThe incidence of prostate cancer is dramatically increasing. Androgen blockade is widely utilized in the management of metastatic and locally advanced prostate cancer. Despite the benefits of this treatment, side effects and shortcoming of quality of life (QoL) constitute the major drawbacks of the hormonal treatment. The proper approach includes precautions in order to provide a lesser impairment in QoL. Therefore, physicians should consider the complications of hormonal treatment and should inform their patients. This review was prepared to point out the QoL changes regarding the hormonal treatment.Publication Open Access Diagnosis of Testicular Torsion and Differentiation From Other Pathologies Using Near-Infrared Spectroscopy(2023-01-01) ŞEKERCİ, ÇAĞRI AKIN; YÜCEL, SELÇUK; ÇAM, HAYDAR KAMİL; Ali Üncü Y., ŞEKERCİ Ç. A., YÜCEL S., Sircan-Kucuksayan A., ÇAM H. K., Savaş M., Yıldırım A., Ağras K., Baykara M., CANPOLAT M.© 2023 Elsevier Inc.Objective: To develop a near-infrared (NIR) spectroscopy device to diagnose testicular torsion with high sensitivity and specificity. Specifically, we aim to investigate the differentiation between testicular torsion from other pathologies such as orchidoepididymitis, varicocele, and hydrocele. Methods: Two LEDs with wavelengths of 660 nm and 940 nm were used as light sources in the device. Each wavelength was sent to the testicle successively, and a photodiode detected back-reflected diffuse light. The ratio of the light intensities of 660 nm and 940 nm was used as a diagnostic parameter. A multi-center clinical trial was performed in 5 different hospitals. Results: In total, 62 patients in urology clinics with acute testicular pain have been recruited for the study. The developed NIR spectroscopy correctly defined all 8 testicular torsion cases. Besides, 3 orchidoepididymitis, 1 varicocele, and 3 hydrocele cases were correctly distinguished from testicular torsion. Only 1 hydrocele case was misdiagnosed as torsion. The range of the ratio was between 0.14 and 1.16 overall measurements. The ratio varied between 0.14 and 0.3 for the testicle with torsion. The ratio was between 0.49 and 1.16 for the normal testicle and testicle with other pathologies mentioned above. Conclusion: We have chosen the threshold ratio of 0.4 to differentiate between the normal and torsion testis and diagnosed all the torsion cases among all normal and other pathologies. The developed optical device to diagnose testicular torsion is inexpensive, user-friendly, and works based on objective criteria with high sensitivity and specificity in real time.Publication Open Access Atypical Cell'' Parameter in Automated Urine Analysis for the Diagnosis of Bladder Cancer: A Retrospective Pilot Study(GALENOS YAYINCILIK, 2020-04-01) FİLİNTE, DENİZ; Tinay, Ilker; Sahin, Bahadir; Saracoglu, Sertac; Yanilmaz, Ozgur; Aksu, Mehmet Burak; Ayas, Ramazan; Filinte, Deniz; Cam, Haydar Kamil; Ilki, ArzuObjective: To evaluate the application of an automated urine analyzer (AUA) for the diagnosis of bladder cancer (BC) Materials and Methods: A retrospective data analysis of 2365 urine specimens from the department of urology has been performed and matched with those patients, who have undergone cystoscopic evaluation or surgical treatment for different urological pathologies during 2018. After matching, clinical records of the patients has been further evaluated in order to select patients with recent or previous BC diagnosis. To assess the diagnostic efficacy of AUA, patients were divided into five groups according to the patient history of BC and healthy controls. Results: A total of 106 patients are included in this study and the majority (69.8%) of the patients are follow-up patients with previous diagnosis and treatment of non-muscle invasive BC (NMIBC). For patients with low-risk NMIBC (n=27), the sensitivity and specificity were calculated as 75% and 100%. For patients with high-risk NMIBC (n=47), who were previously treated with intravesical BCG, the sensitivity and specificity were calculated as 54.5% and 83.3%. All patients in radical cystectomy group (n=7) with muscle invasive BC had positive urine analyses results for atypical cells. And none of the patients in the control group (n=8) had positive AUA results and cystoscopic evaluation also did not show any bladder mass suspicious for BC. Conclusion: The results of this retrospective pilot study showed acceptable sensitivity and specificity rates of the fluorescence flow cytometry based AUA and the results of the low-risk group are especially valuable regarding its potential use to decide on performing a follow-up cystoscopy or not. A prospective study is currently on progress to validate the findings of the current study.Publication Open Access Risk factors of patients with prostate cancer upgrading for international society of urological pathology grade group I after radical prostatectomy(2022-01-01) ÖZGÜR, GÜNAL; FİLİNTE, DENİZ; ÇAM, HAYDAR KAMİL; ÖZGÜR A., ÖZGÜR G., ŞAHİN B., FİLİNTE D., TİNAY İ., ÇAM H. K., TÜRKERİ N. L.Objective: This study aimed to determine the predictive factors for patients whose International Society of Urological Pathology (ISUP) score was upgraded in radical prostatectomy (RP) pathologies with a prostate biopsy pathology of ISUP grade group 1. Materials and Methods: Among patients who underwent RP in our clinic within 10 years, 158 patients with prostate biopsy pathology of ISUP grade group 1 were examined retrospectively. Age, serum prostate-specific antigen (PSA) level, prostate biopsy ISUP grade group, number of cores taken in the prostate biopsy, number of tumor-positive cores, RP pathology ISUP grade group, and pathological stage were evaluated. Results: The mean age (± standard) of the 158 patients whose prostate biopsy pathology was ISUP grade group 1 were 64.07 (±6.6). ISUP group upgrading was detected in 47 patients (29.7%). The mean PSA value of these patients was 10.6 ng/mL (±6.9). The mean PSA value of the other 111 patients without ISUP group upgrading was 7.98 ng/mL (±4.9). The serum PSA level was significantly higher in patients with upgraded ISUP in the RP pathology (p=0.02). The percentage of tumor-positive cores in the group with ISUP group upgrading (37%) was significantly higher than that in the group without ISUP group upgrading (27%) (p=0.01). The detection rates of surgical margin positivity (42.6% vs. 18%), capsule invasion (55.3% vs. 19.8%), and seminal vesicle invasion (23.6% vs. 3.6%) were also significantly higher in the upgraded ISUP group after RP (p<0.05). Conclusion: The results of this trial suggest that active surveillance may not be an appropriate option for patients with biopsy ISUP grade group 1 with PSA level >10 ng/mL. Moreover, the presence of a higher number and percentage of tumor-positive cores constituted risks of ISUP group upgrading with concomitant poor pathological outcomes such as surgical margin positivity, capsule invasion, and seminal vesicle invasion.