Person: PEKER, MEHMET SERTAÇ
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PEKER
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MEHMET SERTAÇ
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Publication Open Access Assessment of adjustment disorder in people with COVID-19 infection(2023-01-01) PEKER, MEHMET SERTAÇ; TOPUZOĞLU, AHMET; PEKER M. S., TOPUZOĞLU A.Objective: This study aimed to evaluate the development of adjustment disorder according to the ADNM-20 (Adjustment Disorder New Module-20) scale in participants who were followed up for Covid-19 infection. Methods: A cross-sectional survey was conducted from September to November 2020. After sample size calculation, we aimed to reach minimum 170 people out of 1290 people who applied to the hospital for Covid-19 disease treatment. Participants were selected from the patients admitted to the hospital using a simple stratified random sampling method. We reached 182 people after treating the patients who were followed up with Covid-19 infection in a University Hospital in Istanbul, Turkey. A questionnaire and the Adjustment Disorder New Module-20 scale were applied via phone / mail at the end of the 6th month after Covid-19 related hospital admission by researchers. Results: Adjustment disorder was found in 28.8 % (n=42) of the participants disorder according to the ADNM-20 scale. While the rate of development of adjustment disorder due to Covid-19-related stress was 26.7 % (n=39); the rate of development of adjustment disorder due to non-Covid-19 stress was found to be 2.1 % (n=3). With the increase in stress load, the development of adjustment disorder increased significantly. The frequency of developing Covid-19-related stress-related adjustment disorder was statistically significantly increased with the duration of exposure to stress. Conclusion: We have found out that one out of every four people who apply to the hospital for healthcare services due to Covid-19 infection may develop an adjustment disorder. Assessment of the adjustment disorder more frequently and making early interventions may contribute to the prevention of progressive mental disorders.Publication Metadata only Effectiveness of Photoactivated Disinfection in Experimentally Infected Root Canals(2014-04-24) PEKER, MEHMET SERTAÇ; KADİR, TANJU; GERNİ P. M., UYGUN CAN B., PEKER M. S., KADİR T., GÜNDAY M.Publication Metadata only Oral health and related factors in a group of children with cystic fibrosis in Istanbul, Turkey(WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2015) YARAT, AYŞEN; Peker, S.; Kargul, B.; Tanboga, I.; Tunali-Akbay, T.; Yarat, A.; Karakoc, F.; Ersu, R.; Dagli, E.Background: Cystic fibrosis (CF) patients can be considered as high caries risk patients because they frequently consume sugar-rich food between meals and they have a high intake of sugar containing syrups, aerosols, and salivary flow reducing medication. Variable caries prevalences were reported in CF patients in previous studies. There are no studies related to CF and salivary thromboplastic activity, which can be presented as a marker of wound healing and bleeding tendency of oral cavity. Objective: The aim of this study was to compare oral health status and salivary pH, flow rate, and thromboplastic activity in children with CF and healthy controls. Materials and Methods: A sample of 35 children with CF (23 girls and 12 boys), and 12 healthy control subjects (6 girls and 6 boys) were selected. Caries experience, oral hygiene, and dental erosion were assessed. Salivary flow rate, pH, thromboplastic activity, and total protein content were determined. Differences between the groups were evaluated using Chi-square test with a significance level set at 0.05. Results: The differences between children with CF and healthy controls in tooth brushing frequency, use of fluoride tablets, caries experience, dental erosion index, oral hygiene index, salivary flow rate and total protein levels were not statistically significant (P > 0.05). Salivary thromboplastic activity of the CF group was significantly lower than the healthy controls (P < 0.01). Conclusion: Large population studies may be necessary to establish the role of salivary thromboplastic activity in children with CF considering our findings related to the decreased salivary thromboplastic activity, which may indicate delayed oral wound healing process.Publication Open Access Possible Medical Aetiological Factors and Characteristics of Molar Incisor Hypomineralisation in a Group of Turkish Children(2013-12-15) DURMUŞ, BAŞAK; Durmus, Basak; Abbasoglu, Zerrin; Peker, Sertac; Kargul, BetulPublication Metadata only Do ginger extract, natural honey and bitter chocolate remineralize enamel surface as fluoride toothpastes? an in-vitro study(Wolters Kluwer Medknow Publications, 2021) KARGÜL, BETÜL; Celik Z.C., Yavlal G.O., Yanikoglu F., Kargul B., Tagtekin D., Stookey G.K., Peker S., Hayran O.Background: In recent literatures, much attention has been given to natural products for their health benefits. Aims: In this study, the objective was to measure the efficacy of the ginger-honey-chocolate mixture as the remineralization effect has been shown in the literature previously and to evaluate the individual contributions of this mixture; ginger, natural honey, bitter chocolate separately on remineralization of initial enamel caries lesion. Materials and Methods: All specimens were divided into eight groups as: Ginger (Arifoglu®, Turkey) in powder form, (n = 8); Ginger-Honey-Chocolate (n = 8); Natural honey (Balparmak Plateau Blossom Honey®, Turkey) (n = 9); Bitter chocolate (Nestlé®, Switzerland) (n = 8); MI Paste (GC, Japan) (n = 8); Paradontax (Sensodyne, Glaxosmithklein, USA) (n = 9); Pronamel (Sensodyne, Glaxosmithklein, USA) (n = 9); Control (n = 9) groups. Samples were carried out five pH cycles along 7 days at 37°C for each group. During pH cycling, blocks were put in a demineralization (6 h) and a remineralization solution (18 h). The treatment consisted of 1 min. interaction of enamel surfaces with agent/deionized slurries (1:3 w/w) on a daily basis. The surface microhardness (SMH) was determined before and after pH cycling with a Digital Micro-Vickers Hardness Tester (Wilson Wolpert; Europe BV, 401 MVD, Netherlands). Mineral changes were determined by using FluoreCam® and recovery values were calculated as SMHR% and FΔ%, respectively. Results: All groups showed an enhanced remineralization. There was no significant difference in terms of FΔ% (F = 1.223, P = 0.304) and SMHR% (F = 0.709, P = 0.664) between all groups. Conclusion: The herbals (ginger, honey, and bitter chocolate) examined in this study gave promising results with a high remineralization potential. © 2021 Wolters Kluwer Medknow Publications. All rights reserved.Publication Metadata only Evaluation of human enamel surfaces treated with theobromine: A pilot study(Quintessence Publishing Co., Ltd, 2012) KARGÜL, BETÜL; Kargul B., özcan M., Peker S., Nakamoto T., Simmons W.B., Falster A.U.Purpose: The objectives of this in-vitro study were to investigate the effect of theobromine, which is the principle xanthine species in Theobroma cacao, at two concentrations on the surface hardness and topography of human enamel. Materials and Methods: Twenty-four freshly extracted human third molars were collected and stored in distilled water with 0.1% thymol solution at room temperature prior to the experiments. The enamel specimens were treated with one coat of theobromine at two concentrations (100 mg/l or 200 mg/l in distilled water) for 5 min. Enamel surfaces in the control group received no theobromine. They were then kept in distilled water for 1 week and subjected to SEM analysis. The specimens were demineralised by storing them in acidic hydroxyethylcellulose for three days. After baseline microhardness measurements, they were incubated either in 100 or 200 mg/l theobromine for 5 min. The control group was kept in distilled water. After washing the specimens under distilled water, they were kept in a remineralising solution for 18 h. Microhardness of the enamel surface was initially determined for each specimen before artificial demineralisation. After demineralisation, the experimental groups were incubated in 100 mg or 200 mg theobromine and control-group specimens were placed in remineralising solution. Results: Enamel surfaces of the untreated control group presented a generally smooth and slightly hummocky surface with small lines of pits. Specimens treated with theobromine showed differences between the two concentrations. The group treated with 200 mg/l solution for 5 min showed a greater quantity of globules on enamel than did specimens treated with 100 mg/l solution. Conclusion: As shown by the microhardness values, a consistent and remarkable protection of the enamel surface was found with the application of theobromine.Publication Metadata only Related factors of dental caries and molar incisor hypomineralisation in a group of children with cystic fibrosis(Springer Verlag, 2014) KARGÜL, BETÜL; Peker S., Mete S., Gokdemir Y., Karadag B., Kargul B.Aim: To investigate dental caries and molar incisor hypomineralisation (MIH)-related factors such as treatment, diet, brushing and salivary factors in children with cystic fibrosis (CF) compared with healthy peers. Study design: A cohort study was performed. Methods: This study was performed on 30 CF children comprising patients at the Faculty of Medicine and 30 control children recruited from the Dental School. Salivary factors, dental caries, MIH, daily diet, brushing habits were analysed. Statistical analysis was calculated by SPSS for Windows. Results: Decay missing filled teeth (DMF-T) score was 4.6 ± 4.0 in CF and 7.7 ± 2.7 in control (p = 0.001). 43 % of CF children with MIH were found to use antibiotics, but no significant difference in the caries experience was found with antibiotic usage (p > 0.05). DMF-T of CF adolescents (23 %) who use Tobramycin was 7 ± 3.5. DMF-T of CF children (20 %) who take other antibiotics was 2.5 ± 3.5, but no statistical difference was found (p = 0.054). Saliva pH, salivary flow rate, and buffering capacity were not found statistically significant (p > 0.05). Statistics: Percentage arithmetic mean value, standard deviation, independent sample t test, Fisher's exact test, Chi-square test and Mann-Whitney U test were used, while a p value of <0.05 was considered statistically significant. Conclusions: Medication and diet could be considered as a risk factor for dental caries and factors such as salivary pH, good oral hygiene could play a protective role for oral health CF children. MIH frequency and lower caries experience seen in CF children could be due to salivary factors or pharmacological treatment they take. The multidisciplinary approach team would be advantageous in the management of children with CF and oral health should be under control during early years of life by paediatric dentists. © 2014 European Academy of Paediatric Dentistry.Publication Metadata only Knowledge and attitudes of Turkish endodontists towards digital radiology and cone beam computed tomography(WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2014) BAŞTÜRK, FATIMA BETÜL; Yalcinkaya, S. Ercalik; Berker, Y. Garip; Peker, S.; Basturk, F. B.Introduction: The aim of this study was to assess the knowledge and attitudes of Turkish endodontists toward digital radiological imaging (DRI) and cone-beam computed tomography (CBCT). Materials and Methods: One hundred and fifty questionnaires were distributed. Questionnaires were given to a sample of endodontists and PhD students in endodontics who attended the 11th International Congress of the Turkish Endodontic Society in Istanbul in 2012. Following the congress, the same questionnaires were sent electronically to endodontists who did not attend the congress. The participants were asked to answer 28 multiple-choice questions concerning their knowledge and practice regarding recent imaging techniques. The questions were subdivided into 2 main topics; general information; general approach to digital imaging. The statistical analysis was carried out by an. 2 chi(2)-test to compare the means at a significance level of P < 0.05. Results: The response rate for this study was 74%. The mean age of the endodontists who participated in this study was 32.74 +/- 10.40 (range 22-61 years). Of the endodontists, 76.6% used digital imaging techniques (DUEs) in their clinics. Statistically significant differences were found between the DUEs and endodontists not using digital imaging (NDUEs), regarding age, gender, graduation year and place of employment (P < 0.01). Endodontists 40-years-old and above had significantly lower knowledge of CBCT compared to the younger groups (P = 0.001). Conclusions: The number of endodontists using digital imaging has been increasing in Turkey. The findings of the present study highlighted the need for adapting to new technologies via continuing education.Publication Open Access A Quantitative Analysis of a Probiotic Storage Media for Avulsed Teeth(UNIV ZAGREB, SCH DENTAL MEDICINE, 2015-03-15) KARGÜL, BETÜL; Esber, Caglar; Sertac, Peker; Ahu, Durhan Muyesser; Pinar, Kulan; Onder, Kuscu Ozgur; Rabia, Pisiriciler; Enis, Ak Caliskan; Betul, Kargul; Nuket, SandalliAim: The aim of the present in vitro study was to investigate the potential of a storage medium, probiotic yogurt (Bifidibacterium animalis DN 173010) in comparison with Hank's balanced salt solution (HBSS), saline and milk in maintaining viable periodontal ligament (PDL) cells on simulated avulsed teeth. Materials and methods: Thirty-six freshly extracted single-rooted human teeth with closed apices were divided into six experimental groups (N=6). The teeth were extracted as atraumatically as possible and washed in sterile saline solution to eliminate residual blood. Following extractions, the coronal 3 mm of PDL tissues were scraped with a #15 scalpel to remove cells that may have been damaged. The positive and negative controls corresponded to 0 minutes and an 8-hour dry time, respectively. After extraction, the positive control teeth were immediately treated with dispase and collagenase. The negative control teeth were bench-dried for 8 h, with no follow-up storage solution time, and then placed in the dispase and collagenase. The number of viable protective least significant difference PDL cells were counted under a light microscope with a hemocytometer at 20x magnification and analyzed. Statistical analysis of the data was accomplished using Nonparametric ANOVA complemented by Kruskal-Wallis Test and Dunn's Multiple Comparisons Test. Results: Positive control was found to be significantly better than the others, there were statistically significant differences between positive control and other test groups (p=0.000). The teeth stored in positive control demonstrated the highest number of viable PDL cells followed in order by probiotic yogurt, HBSS, saline and milk. Conclusion: Bifidibacterium animalis DN 173010 seems to be an alternative for the temporary storage of avulsed teeth, due to high number of viable PDL cells. Probiotics may be suitable transport media for avulsed teeth, but further research is warranted using the commercially available products.Publication Open Access Parent's report on oral health-related quality of life of children with cystic fibrosis(2022-10-01) PEKER, MEHMET SERTAÇ; GÖKDEMİR, YASEMİN; ERDEM ERALP, ELA; KARADAĞ, BÜLENT TANER; KARGÜL, BETÜL; Sisman H. I. , Peker S., GÖKDEMİR Y., ERDEM ERALP E., KARADAĞ B. T. , KARGÜL B.Background Health-related quality of life (HRQoL) scales are now widely used in children with cystic fibrosis (cwCF) which reflects the course of the disease. In this cross-sectional study, our primary aim was to compare the Pediatric Oral Health-Related Quality of Life (POQL) and Oral Health Score (OHS) between cwCF and healthy group. Our secondary aim was to evaluate the association between Pseudomonas aeruginosa (PA) colonization, pulmonary function test, OHS and POQL in cwCF. Methods The study population (age ranging 6-14) included 55 cwCF followed at the Marmara University Division of Pediatric Pulmonology compared with 50 healthy peers. A survey consisted of general questions (age, sex, etc.) and the POQL instrument were filled by parents. The decayed, missing, and filled teeth for both primary (dft) and permanent dentition (DMFT) was detected according to WHO criteria. Data like current body mass index (BMI z score), colonization status with PA, predicted value for forced expiratory volume in 1 second (FEV1pp), and any hospitalizations during the previous year were obtained from their medical. Differences between the groups were evaluated using Chi-square and Mann-Whitney U test with a significance level set at 0.05. Results There was no significant difference between PA-colonized cwCF and healthy controls in DMFT (p = 0.916). For all domains of POQL (emotional function, social function, role function), scores of cwCF were significantly better than healthy controls (p 0.05). Conclusion Although POQL scores of cwCF were encouraging, dental caries prevention and regular follow-ups should be taken into consideration.