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ASLAN, BÜLENT

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ASLAN

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BÜLENT

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Now showing 1 - 5 of 5
  • Publication
    How do presentation age and CSF opening pressure level affect long-term prognosis of pseudotumor cerebri syndrome in children? Experience of a single tertiary clinic
    (Springer Science and Business Media Deutschland GmbH, 2021) DAĞÇINAR, ADNAN; Ozturk G., Turkdogan D., Unver O., Dericioglu V., Aslan B., Dagcinar A.
    Background: Diagnosis and treatment of pseudotumor cerebri syndrome in children is still a challenge for clinicians. The aim of this study is to reveal the influence of presentation age and CSF opening pressure on long-term prognosis of pseudotumor cerebri and share our clinical data of the very young age (≤ 5-year) group. Method: This retrospective study includes the patients followed by the Marmara University Pediatric Neurology Clinic between years 2012 and 2020 diagnosed with definite, probable, or suggestive pseudotumor cerebri syndrome according to modified Friedman criteria. Patients were classified into three groups according to presentation age: group 1: ≤ 5 years old; group 2: 6–10 years; and group 3 > 10 years old. CSF opening pressure was also categorized into three groups as CSF < 20 cmH20; CSF 20–30 cmH20; and CSF > 30 cmH20. Results: One hundred three patients, 62.1% female (n = 64), were enrolled in the study. Group 1 consisted of 16 patients (60% male), group 2 consisted of 30 patients (63.3% female), and group 3 consisted of 57 patients (66.7% female). The mean CSF opening pressure did not differ between the three age groups in our study (p > 0.05). Treatment response was not correlated with CSF opening pressure. Papilledema presence and level of CSF opening pressure were independent of age (p > 0.05). Conclusions: Age at presentation and CSF opening pressure at diagnosis are not any predictive factors that influence long-term prognosis of pseudotumor cerebri syndrome in children. Evaluation and follow-up of children should be done in personalized approach. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
  • PublicationOpen Access
    De novo myeloid sarcoma as a rare cause of small bowel obstruction: CT findings and histopathologic correlation
    (2019-12) ASLAN, BÜLENT; Aslan, Bülent; Tüney, Davut; Erçetin, Yiğit; Bozkurt, Süheyla Uyar; Uprak, Tevfik Kıvılcım
  • Publication
    Kistik Fibrozisli bir olguda nadir pankreatik tutulum: pankreatik sistozis
    (2021-10-31) YAPICI, ÖZGE; ASLAN, BÜLENT; ŞAHİN AKKELLE, BİLGE; ÇİMŞİT, NURİ ÇAGATAY; ALMUS E., YAPICI Ö., ALMUS F., ASLAN B., ŞAHİN AKKELLE B., ÇİMŞİT N. Ç.
  • Publication
    Walker-Warburg sendromu olgusunda klinik ve radyolojik görüntüleme bulguları
    (2021-03-16) ASLAN, BÜLENT; AKBEYAZ, İSMAİL HAKKI; ÇİMŞİT, NURİ ÇAGATAY; YAPICI, ÖZGE; BIYIKLI, ERHAN; Aslan B., Yapıcı Ö., Almus E., Bıyıklı E., Akbeyaz İ. H., Çimşit N. Ç.
    Walker Warburg Sendromu Olgusunda Klinik ve Radyolojik Görüntüleme Bulguları. Amaç: Walker-Warburg sendromu (WWS) nadir görülen letal konjenital müsküler distrofi formudur. Otozomal resesif kalıtım formu özelliğine sahip bu hastalık serebral, serebellar, göz ve kas anomalileri ile karakterizedir. HARDE (Hidrosefali, Agiri, Retinal Displazi, Ensefalosel) sendromu olarak da adlandırılmıştır. Bu sendromun tanısı için tip II lizensefali, serebellar anomali, retinal anomali ve konjenital müsküler distrofiden oluşan 4 kriter gereklidir.Ayrıca Talenti ve ark 2021’de yayımladıkları bir makalede 13 WWS’li olgunun 12’sinin görüntülemesinde kohlear orta ve apikal dönüşlerin hipoplazik ve anteromediale deplese ol duğu tip 4 kohlear hipoplazi formunu saptamışlardır.3 Biz de bu yazımızda, klasik WWS radyolojik bulgularına ek olarak yeni tanımlanmış tip 4 kohlear hipoplazisi de bulunan olgumuzu sunmayı amaçladık. Olgu: Bir aylık erkek hasta, hastanemiz çocuk acil servisine nöbet nedeniyle başvurmuştur. Antenatal takiplerinde hidrosefalisi saptanan olgunun, dış merkezde 27 gün boyun ca yenidoğan yoğun bakım ünitesinde tekrarlayan nöbetler nedeniyle takip edildiği öğrenilmiştir. Fizik muayenesinde hipotonik olan olgunun laboratuvar incelemelerinde kreatin fosfokinaz değeri ileri düzeyde yüksek bulunmuştur. Acil servisimizde çekilen bilgisayarlı tomografi (BT) incelemesinde belirgin triventriküler hidrosefali, serebellar hipoplazi/displazi, malforme beyin sapı ve tip 4 kohlear hipoplazi saptanan olguya ileri tetkik olarak manyetik rezonans görüntüleme (MRG) yapılmıştır. MRG’de tip 2 (cobblestone) lizensefali, triventriküler hidrosefali, Z şeklinde büklüntülü beyin sapı, mikrokistlerin eşlik ettiği serebellar hipoplazi/ displazi ve korpus kallosum agenezisi izlenmiş olup WWS ile uyumlu olarak değerlendirilmiştir. Tanının konulmasından yaklaşık 3 ay sonra olgumuz exitus olmuştur. Sonuç: Nadir bir sendrom olmakla birlikte Walker-Warburg sendromun tanısı klinik/laboratuvar ve görüntüleme ile yüksek doğrulukla konulabilmektedir. Günümüzde kesin tedavisi olmayan sendromun tanısının konulması ebeveynlere genetik danışmanlık verilmesi açısından da büyük önem arz etmektedir. Anahtar Kelimeler : Hidrosefali, Konjenital müsküler distrofi, Walker-Warburg sendromu
  • PublicationOpen Access
    Differences between radiological findings of COVID-19 and non-COVID-19 infections in pediatric patients
    (ZHEJIANG UNIV PRESS, 2021-02) KARAHASAN, AYŞEGÜL; Kuzan, Beyza Nur; Aslan, Bulent; Kuzan, Taha Yusuf; Yagci, Aysegul Karahasan; Cimsit, Nuri cagatay
    Background This study aimed to reveal the differences between coronavirus disease 2019 (COVID-19) infections and non-COVID-19 respiratory tract infections in pediatric patients. Methods Sixty pediatric patients admitted to the hospital between March 11, 2020 and April 15, 2020 with respiratory tract infections were evaluated retrospectively. Among them, 20 patients with reverse transcription-polymerase chain reaction (RT-PCR) tests and chest computed tomography (CT) examinations were included in the study. According to the RT-PCR test results, the patients were divided into the COVID-19 and non-COVID-19 groups. The clinical observations, laboratory results, and radiological features from the two groups were then compared. Results According to the RT-PCR test results, 12 patients were assigned to the COVID-19 group and 8 to the non-COVID-19 group. There were no significant differences between the two groups in terms of clinical or laboratory features. In terms of radiological features, the presence of bronchiectasis and peribronchial thickening was statistically significantly higher in the non-COVID-19 group (P = 0.010 and P = 0.010, respectively). Conclusions In pediatric cases, diagnosing COVID-19 using radiological imaging methods plays an important role in determining the correct treatment approach by eliminating the possibility of other infections.