Person: SAVE, DİLŞAD
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SAVE
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DİLŞAD
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Publication Metadata only Oti̇zmde spor etki̇nli̇kleri̇ni̇n davranış ve sosyalleşme üzeri̇ndeki̇ olasi etki̇leri̇ni̇ değerlendi̇ren ni̇teli̇ksel bi̇r çalışma(2022-12-01) LÜLECİ, NİMET EMEL; KARAVUŞ, MELDA; SAVE, DİLŞAD; HIDIROĞLU, SEYHAN; Peker Ş., Hıdıroğlu S., Karavuş M., Tepe P., Akçabey S., Kaya A. Ö., Öztürkçü H., Lüleci N. E., Save D.Publication Metadata only Prevalence of headache and its association with sleep disorders in children(ELSEVIER SCIENCE INC, 2007) ARMAN, AYŞE; Isik, Ugur; Ersu, Refika Hamutcu; Ay, Pinar; Save, Dilsad; Arman, Ayse Rodopman; Karakoc, Fazilet; Dagli, ElifAn association between headache and sleep disturbances has been reported in previous studies, but there is a lack of research examining this relationship in a community sample of children in order to reveal the magnitude of the problem. Among 32 District Educational Directorates in Istanbul, nine school districts and within each district eight schools were randomly selected. A questionnaire consisting of sociodemographic variables and evaluating headache and sleep disturbances was sent to students' homes to be completed by their parents. The prevalence of headache was 31.4% (95% confidence interval: 29.5-33.4%). Migraine prevalence was 3.3%, whereas nonmigraine headache prevalence was 28.1%. The prevalence of headache was similar between males and females (29.6% vs 33.3%, P > 0.05). The frequency of headache increased with age for both sexes. Snoring, parasomnias, sweating during sleep, and daytime sleepiness were more common among children with migraine compared with nonmigraine and no headache groups. Headaches are common among schoolchildren. Because children with migraine headaches have a high prevalence of sleep disturbances, they should always be evaluated for the presence of sleep problems. (c) 2007 by Elsevier Inc. All rights reserved.Publication Metadata only A comparison of the efficacy and safety of a half dose of fluticasone propionate with beclamethasone dipropionate and budesonide in childhood asthma(2001) KARADAĞ, BÜLENT TANER; Karakoç, F.; Karadag, B.; Kut, A.; Ersu, R.; Bakaç, S.; Cebeci, D.; Dagli, E.This study was carried out in an attempt to compare the efficacy and safety of fluticasone propionate (FP) at the half dose of budesonide (BUD) and beclamethasone dipropionate (BD) in childhood asthma. Ninety-six children with moderate to severe asthma (9.6 +/- 2.17 years) whose asthma was already controlled on BUD (n = 52) or BD (n = 44) were recruited into the study. In the first part of the study (the first 12 weeks) each group was followed with three weekly lung function measurements, daily diary records, and peak expiratory flow (PEF) measurements on the initial medication. At the end of 6 weeks, drugs were switched to a half dose of FP, and the subjects were followed for another 6 weeks. Blood samples were obtained for osteocalcin and plasma cortisol levels after each treatment period. In the second part of the study, 50 patients continued to take FP at the half dose of BUD or BD for another 30 weeks. Clinic visits, including lung function and PEF measurements, were conducted every 10 weeks. After 6 weeks of FP treatment, there was a small but statistically significant decrease in FEV1 and FEF(25-75) in both groups (BUD and BD) without any significant obstruction. These mild changes in lung function measurements continued during long-term follow-up. However, there was no statistically significant further decrease in any lung function parameters while receiving FP (visits 3-8) (coefficient = -0.00751 L/day, p = 0.39 for FEF(25-75) and coefficient = -0.00910 L/sec/day, p = 0.055 for FEV1). There were no significant changes in the morning and evening PEF measurements and diurnal PEF variations after 6 weeks of treatment with FP compared with BUD and BD treatments. There were no significant changes in basal cortisol and osteocalcin levels before or after 6 weeks of FP treatment (p > 0.05). The present study concluded that, although FP at the half dose of BUD or BD seems to maintain reasonable control of the disease symptoms, a mild but significant and persistent decrease in lung function parameters may indicate that FP may not be twice as potent as BUD or BD in childhood asthma by evaluation of lung functions. This conclusion must be further verified with long-term studies.Publication Metadata only The opinion of physicians who participated in community-oriented primaryhealth care work shop during their medical education: a qualitative study(2023-03-03) HIDIROĞLU, SEYHAN; SAVE, DİLŞAD; KARAVUŞ, MELDA; Keser N. B., Hıdıroğlu S., Sancaktar Demiröz M., Özgün F., Efe F., Okur Z., Öztürk M., Çetin M. Ş., Karavuş M., Save D.Publication Metadata only Auditory neuropathy in hyperbilirubinemia: Is there a correlation between serum bilirubin, neuron-specific enolase levels and auditory neuropathy?(TAYLOR & FRANCIS LTD, 2004) TÜRKDOĞAN, DİLŞAD; Akman, I; Ozek, E; Kulekci, S; Turkdogan, D; Cebeci, D; Akdas, FThis study evaluated whether a correlation exists between increased serum bilirubin and neuron-specific enolase (NSE) assays (a biochemical index of neuronal damage) and auditory neuropathy. Nineteen term neonates without hemolysis whose serum bilirubin levels were above 20 mg/dl and 27 healthy term newborns with bilirubin levels <13 mg/dl were included in the study. Auditory brainstem responses (ABRs) and transient evoked otoacoustic emissions (TEOAEs) of patients with hyperbilirubinemia were obtained before discharge. This preliminary study did not show any correlation between the serum NSE and bilirubin values. However, infants who had auditory neuropathy had significantly higher NSE levels, and thus these patients, being in the high-risk group, need close follow-up.Publication Metadata only Evaluation of the impact of the COVID-19 pandemic on routine care of people with chronic disease: a qualitative study(2023-04-01) AYVAZ, İLKNUR; ALTAŞ, ZEYNEP MEVA; SAVE, DİLŞAD; Ayvaz İ., Altaş Z. M., Ekincikli B. T., İpsalalı H. O., Turan S. İ., Kunt K. S., Save D.Background and Objective: Restrictions in the COVID-19 pandemic have affected access to healthcare and caused delays in the routine care of people with chronic diseases. The aim of our study is to reveal the impact of the COVID-19 pandemic on routine care of people with chronic diseases. Methods: Our qualitative study was carried out with 12 people who came to the Cardiology outpatient clinics of tertiary Training and Research Hospital in June 2022 for a routine care due to their chronic diseases. As a data collection tool, a semi-structured questionnaire was used. The data were collected through face-to-face interviews with the participants by taking the necessary protective measures. Thematic analysis method was used in the analysis of the data. After the interviews were transcribed, each transcript was coded using the ATLAS.ti program. The ethics committee approval of the study was obtained. Results: The ages of participants were between 34-73, and 8 of them were male. Participant experiences were categorised into four themes: General Health Status, Routine Care during the Pandemic, Chronic Disease Management during the Pandemic and Patient Expectations of Healthcare. Most of the patients delayed their routine care during the pandemic and their chronic diseases worsened. Among the reasons for not going to the controls, the fear of contagion came to the fore, while some participants mentioned that they could not find an appointment. In terms of their expectations of healthcare, they stated that health institutions should give priority to those with chronic diseases and home health services and online services will provide convenience for them. Conclusion: Delaying hospital admissions for routine care made the management of chronic diseases difficult and worsened the chronic diseases of patients in the long term. Implementation of online health services such as telemedicine can facilitate chronic disease management.Publication Metadata only Annenin depresyonunun önlenmesi ve veya tedavisi ile anne ve çocuk sağlığının iyileştirilmesi Mutlu Anneler Sağlıklı Çocuklar Projesi(2022-04-20) BORAN, PERRAN; BARIŞ, HATİCE EZGİ; US, MAHMUT CANER; HIDIROĞLU, SEYHAN; SAVE, DİLŞAD; BORAN P., DÖNMEZ M., BARIŞ H. E., US M. C., ATIF N., NISAR A., ALTAŞ Z. M., HIDIROĞLU S., SAVE D., RAHMAN A.Giriş Perinatal depresyon gebelik ve doğum sonrası ilk bir yılda ülkemizde %19.2 sıklıkla yaygın olarak görülmektedir. Dünya Sağlık Örgütünün rehberine göre perinatal depresyona yönelik ilk basamak tedavide önerilen kanıta dayalı Bilişsel Davranışçı Terapi temelli Sağlıklı Düşünme programının (SDP) grup formatında geliştirilmesi ve mevcut gebelik hizmetleriyle bütünleştirilmesine yönelik uygulanabilirlik çalışmasının yapılması amaçlanmıştır. Materyal ve Metot Gebe okulu programıyla bütünleştirilmiş SDP grup müdahalesinin, rutin gebe okulunun bir hemşire tarafından yürütülerek geliştirilmiş hali ile karşılaştırması amacıyla iki kollu pilot randomize kontrollü bir çalışma tasarlanmıştır. Araştırmanın evrenini 8 Nisan 2021-8 Eylül 2021 arasında çevrimiçi yürütülen gebe okulu oturumlarına katılmayı kabul etmiş 12-30 gebelik haftasındaki kadınlar oluşturmuştur. Değerlendirmede nitel ve nicel yöntemlerin karışımı kullanılmıştır. Çalışma başlangıcında ve müdahaleden 4-6 hafta sonra Edinburg Postpartum Depresyon Ölçeği (EPDS), Hasta Sağlık Anketi-9 (PHQ-9), Yaygın Anksiyete Bozukluğu-7 (GAD7), Başa Çıkma Stratejileri Kısa Formu (COPE), Çok Boyutlu Algılanan Sosyal Destek Ölçeği (MSPSS), İlişki Değerlendirme Ölçeği (RAS), Pittsburgh Uyku Kalitesi İndeksi (PSQI), Dünya Sağlık Örgütü Yetiyitimi Değerlendirme Ölçeği (WHODAS) uygulanmıştır. Bulgular 158 kadından 8’i çalışmaya dahil edilme kriterlerini karşılamazken, 34 kadın (%22,6) çalışmaya katılmayı reddetmiştir. Yönlendirilen 99 kadından 91’i (%91,9) başlangıç değerlendirmesini tamamlanarak, 88’i randomize edilmiştir. Randomize edilen kadınların 73’ünün (%83) son değerlendirmeleri tamamlanmıştır. Müdahale grubu depresyon ve kaygı puanlarında 4-6 hafta sonra anlamlı derecede azalma, COPE puanlarında ise artış görülürken, kontrol grubu için ortalama puanlar WHODAS dışında değişmemiştir. Gruplar arasında anlamlı fark saptanmazken, müdahale grubu katılımcılarında daha düşük depresif belirtilere doğru bir eğilim görülmüştür. Sonuç Pilot çalışmadan elde edilen bulgularımız programın kültürel olarak kabul edilebilir, uygulanabilir, mevcut sağlık hizmetleriyle bütünleşebilir olduğunu, kadının iyilik hali dışında evlilik ilişkisi, doğmamış bebekle ilişkisi, sağlıklı yaşam alışkanlıklarının geliştirilmesi gibi yaygın etkilerinin olduğunu göstermektedir. Ayrıca programın grup formatının sosyal destek ağı olarak görüldüğü saptanmıştır. Sonuçlar program etkinliğinin gösterilmesi amaçlı geniş çaplı planlanacak çalışmanın nasıl uygulanabileceğini içermektedir.Publication Metadata only The effects of iron deficiency on infants' developmental test performance(TAYLOR & FRANCIS AS, 2004) SAVE, DİLŞAD; Akman, M; Cebeci, D; Okur, V; Angin, H; Abali, O; Akman, ACAim: To assess the effects of iron deficiency on developmental test scores in infants. Methods: This prospective, single-blind, controlled clinical intervention study was made on 108 children aged 6-30 mo who applied to our paediatric outpatient clinic. The cases were classified as control (n = 31, haemoglobin greater than or equal to11 g/dl, serum ferritin > 12 mug/l, MCV greater than or equal to70 fl), non-anaemic iron deficiency (NAID, n = 40, haemoglobin greater than or equal to 11 g/dl, serum ferritin less than or equal to 12 mug/l, MCV greater than or equal to70 fl) and iron deficiency anaemia (IDA, n = 37, haemoglobin <11 g/dl, ferritin &LE; 12 μg/l, MCV <70 fl) due to their anaemia status. In each group, MCV, haemoglobin and ferritin levels were measured, and Denver Developmental Screening Test (DDST) and Bayley Scales of Infant Development (BSID-I) were administered before and after a 3-mo follow-up. IDA and about half of the NAID subjects were treated with oral iron for 3 mo. Results: Subjects with iron deficiency showed significantly lower developmental test scores both with BSID-I and DDST-II compared to their iron-sufficient peers (p < 0.05). After 3 mo of iron treatment, lower mental developmental test scores were no longer observed among the IDA and NAID groups whose anaemia and iron deficiency were also corrected. No significant differences were found between control NAID and control IDA groups on DGTT-II results after treatment. The difference in motor and mental developmental scores did not appear to depend on environmental and family factors considered in the analyses. Conclusion: These findings support the conclusions that iron deficiency may cause lower mental I and motor test scores in infants and these adverse effects can be improved by iron therapy.Publication Metadata only Do perceived health risks outweigh the benefits of modern contraceptives? A qualitative study in a suburban population in Istanbul, Turkey(TAYLOR & FRANCIS LTD, 2007) TOPUZOĞLU, AHMET; Ay, P.; Hidiroglu, S.; Topuzoglu, A.; Ucar, M. Solakoglu; Kose, O. O.; Save, D.Objectives To evaluate the health concerns and the perceived non-contraceptive benefits of modern contraceptive methods through utilizing qualitative methods. Methods Six focus group discussions were carried out with a total of 53 married women in a socio-economically disadvantaged community in Istanbul, Turkey. Results Women had a vague knowledge of the mechanism of menstruation. Some women believed that the uterus was filled with blood-termed 'dirty blood'-which should be eliminated during menstruation in order to stay healthy. For this reason, amenorrhoea was recognized as the important disadvantage of the progestin-only injectable contraceptives. While the participants mentioned fallacious and exaggerated side effects related to modern methods they did not recognize their non-contraceptive benefits. Most women gained the information concerning side effects through their social networks. Sometimes the information acquired was based on rumours that biased women against the modern contraceptives. Conclusions Women outweighed the risks, some of which were fallacious and exaggerated, against the benefits of modern contraceptives. It is crucial to address health concerns of women and what they 'heard' from their peers during counselling sessions. Also the non-contraceptive health benefits of modern methods should be well emphasized. Since informal sources are prevalent, the effectiveness of peer education should be studied in this community.Publication Metadata only Comparison of oral glucose and sucrose solutions on pain response in neonates(CHURCHILL LIVINGSTONE, 2000) SAVE, DİLŞAD; Isik, U; Ozek, E; Bilgen, H; Cebeci, DIn this study, we aimed to compare the analgesic effect of 30% sucrose and 10% and 30% glucose in a group of healthy term newborns. A total of 113 infants whose heels were pricked for the Guthrie test were included in the study. The babies were randomized into 4 groups, receiving 2 mt of 30% sucrose, 10% glucose, 30% glucose, or distilled water. Response to pain was assessed by mean crying time, recovery time, maximum heart rate, and percent change in heart rate at 1, 2, and 3 minutes. Mean crying times were 60, 102, 95, and 105 seconds in the sucrose, 10% glucose, 30% glucose, and placebo groups, respectively (P =.02). Although mean recovery time was shorter in the sucrose group (102 seconds), there was neither a significant difference between the groups (10% glucose, 121 seconds; 30% glucose, 109 seconds; control group, 132 seconds [P =.09]), nov was there a difference in maximum heart rate and percent change in heart rate at 1, 2, and 3 minutes after heel prick (P =.14 P =.05, P =.53 for the first, second, and third minutes, respectively). However, a statistically borderline difference existed at the end of 2 minutes favoring sucrose (P =.05). We conclude that 30% sucrose is superior to 10% and 30% glucose solutions in relieving pain, showing its primary effect in dying time. As glucose solutions are readily available in neonatal intensive care units and easier to use in routine practice, further trials are needed to evaluate the antinociceptive effect of glucose when combined with other nonpharmacologic methods.
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