Person: BORAN, PERRAN
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BORAN
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PERRAN
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Publication Metadata only Büyükanne/Büyükbabanın çocuk yetiştirmedeki rolleri(Turkiye Klinikleri, 2022-01-01) BORAN, PERRAN; Us M. C., BORAN P.Publication Metadata only İklim değişikliğinin önlenmesinde derneklerin aktiviteleri: toplum bilinçlendirilmesi(Türkiye Klinikleri, 2022-01-01) BARIŞ, HATİCE EZGİ; BORAN, PERRAN; BARIŞ H. E., BORAN P.Publication Metadata only Refugee women's well-being, needs and challenges: implications for health policymakers(OXFORD UNIV PRESS, 2020) BARIŞ, HATİCE EZGİ; Qutranji, L.; Silahli, N. Y.; Baris, H. E.; Boran, P.Background Refugees face circumstances where their health and well-being are compromised. In this qualitative study, the aim was to understand Syrian refugee women's needs for care and the predisposing and enabling factors to healthcare access and utilisation. Methods Out of 945 Syrian mothers who gave birth in our university hospital between 2014 and 2018, 195 were reached; out of which, 47 women were included. Semi-structured in-depth interviews were conducted and were later analysed using a qualitative content analysis approach. Depression was assessed by the Patient Health Questionnaire-9 at the end of the interview. Results Social isolation and maternal depression, language barrier and challenges while navigating the healthcare system emerged as the main themes of the study. Low educational and occupational status of the women, poor social resources, limited Turkish proficiency and unfamiliarity with the host healthcare system were identified as the predisposing factors for poor healthcare services utilisation. Conclusion Recommendations include bridging language gaps, improving the navigation of the healthcare system by visual support or in-person interpretation, and psychosocial support. Providing hospital-based language courses to mothers and social integration programs for families will improve the mothers' well-being and indirectly care of the child.Publication Metadata only Effects of caffeine therapy for apnea of prematurity on sleep and neurodevelopment of preterm infants at 6 months of corrected age(2023-12-01) BARIŞ, HATİCE EZGİ; ÖZDEMİR, HÜLYA; ERDEM ERALP, ELA; ÖZEK, EREN; BORAN, PERRAN; Yola Atalah Y. E., Barış H. E., Küçük Akdere S., Sabancı M., Özdemir H., Gücüyener K., Erdem Eralp E., Özek E., Boran P.Publication Open Access Delivering the thinking healthy programme as a universal group intervention integrated into routine antenatal care: a randomized-controlled pilot study(2023-12-01) BORAN, PERRAN; DÖNMEZ, MELİKE; BARIŞ, HATİCE EZGİ; ALTAŞ, ZEYNEP MEVA; HIDIROĞLU, SEYHAN; SAVE, DİLŞAD; BORAN P., DÖNMEZ M., Barış E., Us M. C., ALTAŞ Z. M., Nisar A., Atif N., Sikander S., HIDIROĞLU S., SAVE D., et al.© 2023, The Author(s).Background: Women with perinatal depression and their children are at increased risk of poor health outcomes. There is a need to implement non-stigmatizing interventions into existing health systems which reduce psychosocial distress during pregnancy and prevent perinatal depression. We adapted the WHO-endorsed Thinking Healthy Programme (THP) to be delivered universally to all women attending routine online pregnancy schools in Istanbul, Turkey. This study aimed to evaluate the feasibility and acceptability of this intervention. Methods: This mixed-methods study incorporated a two-arm pilot randomized controlled trial and qualitative evaluation of the feasibility and acceptability of the adapted THP – Brief Group version (THP-BGV) to a range of stakeholders. We recruited pregnant women at 12-30 weeks’ gestation through pregnancy schools within the University Hospital’s catchment area. Women in the intervention arm received five online sessions of the THP-BGV delivered by antenatal nurses. The intervention employed principles of cognitive behaviour therapy to provide psychoeducation, behaviour activation, problem-solving strategies and group support to participants. In the control arm, women received usual care consisting of routine online educational pregnancy classes aided by the antenatal nurses. The women were assessed for depressive symptoms with the Edinburgh Postnatal Depression Scale at baseline and 4-6 weeks post-intervention and also evaluated for anxiety, perceived social support, partner relationship, level of disability and sleep quality. In-depth interviews were conducted with women and other key stakeholders. Results: Of the 99 consecutive women referred to the pregnancy schools, 91 (91.9%) were eligible and 88 (88.8%) consented to participate in the study and were randomized. Eighty-two (83%) completed the final assessments. Our main findings were that this preventive group intervention was feasible to be integrated into routine antenatal educational classes and it was valued by the women and delivery-agents. While the study was not powered to detect differences between intervention and control conditions, we found small trends towards reduction in anxiety and depressive symptoms favoring the intervention arm. No serious adverse events were reported. Conclusions: Given the paucity of preventive interventions for perinatal depression in low and middle-income countries, a fully powered definitive randomized controlled trial of this feasible and acceptable intervention should be conducted. Trial registration: The study was registered at Clinical Trails.gov (NCT04819711) (Registration Date: 29/03/2021).Publication Metadata only Effectiveness of a sleep education program for pediatricians(WILEY, 2017) AY, NADİYE PINAR; Ersu, Refika; Boran, Perran; Akin, Yasemin; Bozaykut, Abdulkadir; Ay, Pinar; Yazar, Ahmet SamiBackground: The high prevalence of sleep problems in children and long-term consequences point to the need for early effective interventions, but health-care providers have limited training in pediatric sleep medicine. The aims of this study were therefore to assess the effectiveness of a sleep health-care education program and to develop a Turkish acronym for brief sleep history taking for pediatric primary caregivers in the ambulatory setting. Methods: This was a quasi-experimental study. Four centers were randomly selected from eight training and research hospitals as the intervention group. The control group was recruited during training in subjects other than sleep. Education was provided to the intervention group. Knowledge and attitudes were evaluated in the short and long term. Results: The intervention and the control groups consisted of 132 and 78 pediatricians, respectively. The intervention group scored significantly higher both in the short and the long term. The Turkish acronym (UYKU) was reported to be easy to remember and effective in prompting the correct questions to ask about sleep issues. Conclusions: The Turkish acronym would be useful in the primary care setting to increase the frequency of screening of sleep problems in children. Although education significantly improved knowledge on sleep issues in children, the percentage of participants who lacked confidence in the management of sleep problems in children was still very high, even in the intervention group. We suggest that a broader educational program, carried out more than once, would be more beneficial.Publication Metadata only The impact of vitamin B12 deficiency on infant gut microbiota(SPRINGER, 2020) ERZİK, CAN; Boran, Perran; Baris, Hatice Ezgi; Kepenekli, Eda; Erzik, Can; Soysal, Ahmet; Dinh, Duy M.Although physiologic and neurologic consequences of micronutrient deficiencies have been addressed extensively, less is known about their impact on developing gut microbiota. Vitamin B12 deficiency is a common micronutrient deficiency in infants. We aimed to analyze the gut microbial composition of exclusively breastfed infants aged between 4 and 6 months with and without vitamin B12 deficiency by 16S rRNA gene sequencing. In a subgroup of infants with vitamin B12 deficiency, stool samples are recollected and reanalyzed after vitamin B12 supplementation. A total of 88 infants' stool samples (median age 4 months [IQR 4-5], 50% males) were analyzed, of which 28 (31.8%) were vitamin B12 sufficient and 60 (68.2%) were vitamin B12 insufficient. Comparisons between vitamin B12-sufficient and vitamin B12-insufficient infants revealed no evidence of differences in the microbiota. Proteobacteria, Firmicutes, Actinobacteria, and Bacteroidetes were the most abundant phyla in all groups. There was no difference between the pre- and post-treatment composition of gut microbiota. Conclusion: Vitamin B12-deficient infants have similar gut microbial composition as vitamin B12-sufficient infants. Since the samples were collected at an early period of life and the exposure to deficiency was relatively short, it may be possible that the effects were not fully established.Publication Metadata only The differences in perinatal outcomes between refugee and resident mother-infant dyads: A retrospective study in Turkey between 2013 and 2018(TAYLOR & FRANCIS INC) ÖZEK, EREN; Silahli, Nicel Yildiz; Baris, Hatice Ezgi; Qutranji, Lubna; Ozek, Eren; Boran, PerranIn this study, we aimed to examine and compare the perinatal outcomes between refugee and resident mother-infant dyads. Data of refugee women who had given birth in a university hospital (n = 924) and matched resident mother-infant dyads (n = 957) were included. Analysis revealed higher adolescent pregnancy rates and lower rates of antenatal care attendance among refugee mothers compared to residents. No significant differences in neonatal outcomes were found, except for a significantly higher number of preterm births among refugee infants. Interventions should be made to ensure antenatal care for all pregnant women, which can also prevent preterm birth.Publication Open Access Impact of lockdown and school closure on children's health and well-being during the first wave of COVID-19: a narrative review(BMJ PUBLISHING GROUP, 2021-05) BORAN, PERRAN; Rajmil, Luis; Hjern, Anders; Boran, Perran; Gunnlaugsson, Geir; Kraus de Camargo, Olaf; Raman, ShantiBackground In the context of containment measures against the COVID-19 pandemic, the aims were to examine the impact of lockdown and school closures on childs' and adolescents' health and well-being and social inequalities in health. Methods Literature review by searching five databases until November 2020. We included quantitative peer-reviewed studies reporting health and well-being outcomes in children (0-18 years) related to closure measures' impact due to COVID-19. A pair of authors assessed the risk of bias of included studies. A descriptive and narrative synthesis was carried out. Findings Twenty-two studies, including high-income, middle-income and low-income countries, fulfilled our search criteria and were judged not to have an increased risk of bias. Studies from Australia, Spain and China showed an increase in depressive symptoms and decrease in life satisfaction. A decrease in physical activity and increase in unhealthy food consumption were shown in studies from two countries. There was a decrease in the number of visits to the emergency department in four countries, an increase in child mortality in Cameroon and a decrease by over 50% of immunisations administered in Pakistan. A significant drop of 39% in child protection medical examination referrals during 2020 compared with the previous years was found in the UK, a decrease in allegations of child abuse and neglect by almost one-third due to school closures in Florida, and an increase in the number of children with physical child abuse trauma was found in one centre in the USA. Interpretation From available reports, pandemic school closure and lockdown have adverse effects on child health and well-being in the short and probably long term. We urge governments to take the negative public health consequences into account before adopting restrictive measures in childhood.Publication Metadata only Emzirme ve relaktasyon polikliniği başvurularını etkileyen faktörler: Maternal depresyon ve anksiyetenin rolü(2023-10-22) US, MAHMUT CANER; BORAN, PERRAN; BARIŞ, HATİCE EZGİ; Dinç Aktekin S., US M. C., BORAN P., BARIŞ H. E.Giriş: Bebek Dostu Hastane Girişimi kapsamında Emzirme Danışmanlığı ve Relaktasyon Polikliniklerinde (EDRP) danışmanlık hizmeti sunulmaktadır. Danışmanlık ihtiyacı olan annelerin özelliklerinin belirlenmesiyle riskli durumlar önceden saptanabilir. Çalışmamızda, EDRP’ne başvuran annelerin özellikleri incelenerek, danışmanlık ihtiyacında etkili faktörlerin belirlenmesi hedeflenmiştir. Materyal ve Metot: Yöntem: Ağustos 2021-Şubat 2023 tarihleri arasında EDRP’ne emzirmede sorun yaşadığı için danışmanlık almak üzere başvuran hastaların dosyaları (n=47) retrospektif incelenerek annelerin depresyon ve anksiyete düzeyleri, bebekler doğum tarihleri ile eşleştirme yapılarak, kontrol grubu olarak seçilen Çocuk Sağlığı İzlem Polikliniği’nde izleme alınan ve emzirme sorunu bildirmeyen annelerinkiyle kıyaslandı (n=47). Maternal depresyon, Edinburgh Postpartum Depresyon Ölçeği (EPDÖ), anksiyete ise Yaygın Anksiyete Bozukluğu-7 (YAB-7) ile değerlendirildi. Kategorik değişkenler % olarak ifade edilip ki kare testi ile, %95 güven aralığı (GA) ve odds oranı (OR), sürekli değişkenler ortanca (çeyreklerarası aralık) olarak ifade edilip Mann Whitney U testi ile karşılaştırıldı. Bulgular: Bebeklerin cinsiyet dağılımı her iki grupta benzerdi (kız:%55,3 ve %40,4). Sezaryen doğum, emzirme danışmanlığı verilen grupta daha sıktı (%71,7 ve %41,3, OR:3,6[1,5-8,6], p=0,003). Gruplar arasında anne yaşı ve eğitim düzeyi açısından anlamlı fark izlenmedi. Emzirme danışmanlığı verilen gruptaki bebeklerin ortanca doğum gestasyon haftası, anlamlı olarak daha erken [38 (36,7-39) ve 39 (38-40), p=0,002] olup, annenin ilk doğumu olma sıklığı daha yüksekti (%70,2 ve %42,6, OR:3,2[1,4-7,5], p=0.007). Danışmanlık verilen annelerin EPDÖ puanı 9 (2-13,5) ve YAB7 puanı 3 (0-7) olup, kontrol grubundan anlamlı olarak daha yüksekti (p<0.001). Oluşturulan bir regresyon modelinde, sezaryen doğum, ilk doğum ve yüksek anksiyete puanları, EDRP başvuruları ile anlamlı olarak ilişkiliydi (Tablo 1). Sonuç: Bulgularımız, ilk defa doğum yapan, sezaryen ile doğum yapan ve anksiyete seviyeleri yüksek olan annelerin, daha yüksek olasılıkla özellikli emzirme danışmanlığına ihtiyacı olabileceğini göstermektedir. Bebek dostu hastanelerde, doğum sonrası emzirme danışmanlığı rutin olarak uygulanmakla birlikte, riskli annelerin yakın takibi, emzirme sürecinde ortaya çıkabilecek sorunların önceden önlenmesinde faydalı olabilir. Postpartum maternal depresyonun yanında anksiyetenin de rutin olarak taranması ve yönetimi, emzirme sorunlarını değerlendirirken ele alınmalıdır.