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GÜMRÜ TARÇIN, BİRSAY

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GÜMRÜ TARÇIN

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BİRSAY

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Now showing 1 - 10 of 29
  • Publication
    Effect of oral antiseptic agents on phospholipase and proteinase enzymes of Candida albicans
    (PERGAMON-ELSEVIER SCIENCE LTD, 2016) GÜMRÜ TARÇIN, BİRSAY; Uygun-Can, Banu; Kadir, Tanju; Gumru, Birsay
    Objective: Candida-associated denture stomatitis is the most prevalent form of oral candida infections among the denture wearers. Generally, antiseptic oral rinses used in the treatment of these infections are considered as an adjunct or alternative antifungal treatment. Studies have suggested that the intraoral concentrations of antiseptics decrease substantially to the sub-therapeutic levels on account of the dynamics of the oral cavity. This condition yields the question about the minimum antiseptic concentration that effect the character or pathogenesis of Candida during treatment. The extracellular phospholipase and proteinase enzymes of Candida albicans are regarded to have a crucial role in the pathogenesis of human fungal infections. Therefore, the aim of this study was to investigate the effect of different sub-therapeutic concentrations of chlorhexidine gluconate, hexetidine and triclosan on the production of these enzymes by C. albicans strains isolated from 20 patients with denture stomatitis. Methods: Phospholipase test was done by using Sabouraud dextrose agar with egg yolk, proteinase test was done by using bovine serum albumin agar. Methods: Phospholipase test was done by using Sabouraud dextrose agar with egg yolk, proteinase test was done by using bovine serum albumin agar. Results: Exoenzyme production of 20 strains which were brief exposured to sub-therapeutic concentrations of three antiseptic agents decreased significantly compared with the strains that were not exposured with antiseptic values (p < 0.05). There was significant difference between the sub therapeutic concentrations of each of three antiseptics (p < 0.05). When the same concentrations of each antiseptic was compared, there were no significant differences between enzymatic activities (p > 0.05). Conclusions: The results of this study show that sub-therapeutic levels of each antiseptic may modulate candidal exoenzyme production, consequently suppressing pathogenicity of C albicans. (C) 2015 Elsevier Ltd. All rights reserved.
  • Publication
    Focal epithelial hyperplasia: a rare case report with 3-year follow-up
    (2022-10-06) BORAHAN, MEHMET OĞUZ; GÜMRÜ TARÇIN, BİRSAY; ERDEM, NECİP FAZIL; AŞKIN EKİNCİ, SENEM; DEVECİ S., BORAHAN M. O., GÜMRÜ TARÇIN B., ERDEM N. F., AŞKIN S., ZENGİNKİNET T.
  • Publication
    Radiologic Assessment of Periapical Health: Comparison of 3 Different Index Systems
    (ELSEVIER SCIENCE INC, 2015) GÜMRÜ TARÇIN, BİRSAY; Tarcin, Bilge; Gumru, Birsay; Iriboz, Emre; Turkaydin, Dilek Erbay; Ovecoglu, Hesna Sazak
    Introduction: The aim of this study was to evaluate observer variations and observer reproducibility in the interpretation of periapical health using the Strindberg system, the periapical index (PAI), and the probability index for radiologic assessment of periapical health. Methods: Four observers read digital periapical images to evaluate the periapical health of 200 root-filled teeth. Each observer evaluated a tooth twice by using the Strindberg system, twice by using the PAI, and twice by using the probability index. Each observation session was held at 1-month intervals. Three scores were used for the evaluations conducted by using the Strindberg system. Both the PAI and the probability index were considered on 5-point scales and were also dichotomized. SPSS for Windows 15.0 software (SPSS InC, Chicago, IL) was used for data analysis, and intra- and interobserver agreements were described by using kappa statistics. Results: The average kappa values of intra- and interobserver agreement calculated for the Strindberg system were 0.53 and 0.36, respectively. The corresponding average kappa values were calculated as 0.48 and 0.39 for the PAI and 0.45 and 0.30 for the probability index. The highest mean proportion values of intra- and interobserver agreement were observed for the dichotomization of the PAI (88.9% and 87.0%, respectively) followed by the dichotomization of the probability index (86.8% and 82.9%, respectively). Conclusions: The Strindberg system has lower intraobserver variation compared with the PAI and the probability index, whereas PAI has lower interobserver variation compared with the Strindberg system and the probability index. The dichotomization of the PAI and the probability index provided higher intra- and interobserver agreement values in the radiologic assessment of periapical health.
  • Publication
    Çocuk ve yetişkinlerde radyolojik dental yaş tayini yöntemleri ve kullanılan radyolojik teknikler
    (Gece Kitaplığı, 2022-01-01) GÜMRÜ TARÇIN, BİRSAY; ERÇALIK YALÇINKAYA, ŞEBNEM; GÜMRÜ TARÇIN B., İDMAN E., ERÇALIK YALÇINKAYA Ş.; Evereklioğlu, Cem; Erten, Mehmet
    ireylerin tanınması, tanımlanması ve diğer bireylerden ayırt edilmesinde yararlanılan özelliklerin bütünü “kimlik”, yaşayan bireylerin ya da cesetlerin bireye özgü bu özelliklerinin çeşitli nedenlerle ortaya konması ise “kimlik tespiti” olarak isimlendirilmektedir (Baransel Isır, 2009; Teke ve ark., 2017).
  • Publication
    Cross-contamination and infection control in intraoral digital imaging: a comprehensive review
    (SPRINGER, 2021) GÜMRÜ TARÇIN, BİRSAY; Gumru, Birsay; Tarcin, Bilge; Idman, Ender
    Dental health care workers are subjected to various infectious disease agents that are present in patients' saliva and blood which make infection control and universal prevention methods indispensable to the dental practice given that some of these diseases cause loss of work and time for dental staff and patients; some of them cause serious morbidity; and some of them currently have a poor prognosis and no effective treatments. Although dental radiographic procedures are not invasive, and there are no incidents such as injuries caused by dental instruments, they are a potential infection source because of contamination with saliva and blood, and comprehensive infection control procedures also apply to the radiology clinic. In addition, contact with a large number of patients in dental schools and clinics in a short period of time, and the fact that radiographic procedures are performed in the same environment as other dental procedures in dental offices increase the significance of infection control in dental radiology. Major advances in computer technology have enabled digital imaging systems to develop rapidly and to become common in dental practice as an alternative to conventional film-based imaging. The use of digital sensors in dental radiology introduced unique infection control challenges and required the revision and modification of existing infection control techniques. In this review, studies concerning the risk of cross-contamination and challenges of infection control with digital image sensors are comprehensively reviewed and infection control protocols that should be followed in intraoral digital imaging using both direct and indirect systems are thoroughly examined.
  • Publication
    Serum cytokine and T regulatory cell levels in patients with burning mouth syndrome
    (WILEY, 2008) GÜMRÜ TARÇIN, BİRSAY; Pekiner, Filiz Namdar; Demirel, Guelderen Yamkkaya; Gumru, Birsay; Ozbayrak, Semih
    BACKGROUND: Burning mouth syndrome is a disorder usually associated with an unexplained, prolonged sensation of burning inside the oral cavity. Although the etiology is unknown, neural and psychologic factors and cytokines may be implicated in the pathogenesis of burning mouth syndrome. The aim of this study was to investigate the relationship between serum cytokine and T regulatory cell levels in patients with burning mouth syndrome with regard to depression and anxiety. METHODS: Thirty patients with burning mouth syndrome and 30 matched controls participated in the study. Serum cytokine levels were measured with cytometric bead array and T regulatory cells were defined as CD4(+)CD25(+)Foxp-3(+) cells by flow cytometry. The level of anxiety and depression were analyzed by means of the Speilberger State-Trait Anxiety Inventory and Zung Self-Rating Depression Scale. Visual analogue scale was used in the quantification of burning levels of patients. RESULTS: Serum IL-2 and TNF-alpha levels were significantly decreased in patients with burning mouth syndrome compared with controls [mean 16.79 +/- 8.70 vs. 37.73 +/- 41.05 pg/ml (P < 0.05) and mean 39.09 +/- 29.40 vs. 70.83 +/- 42.44 pg/ml (P < 0.01) respectively]. CONCLUSIONS: IL-2 and TNF-alpha might play a role in burning mouth syndrome. Burning mouth syndrome may occur as a sign of predisposition to autoimmunity. Presence of low levels of CD28(+) supports the provision that BMS might be a pre-otoimmune disease.
  • Publication
    Analysis of Risk Factors for Prosthesis-Related Oral Mucosal Lesions: A Retrospective Study
    (2021-09-24) GÜMRÜ TARÇIN, BİRSAY; ERÇALIK YALÇINKAYA, ŞEBNEM; BAYRAMOV N., GÜMRÜ TARÇIN B., ERÇALIK YALÇINKAYA Ş.
  • Publication
    Erythema Multiforme: A retrospective study of aetiological associations, clinical manifestations, and treatment
    (2023-10-26) GÜNGÖR, TUĞÇE; GÜMRÜ TARÇIN, BİRSAY; GÜNGÖR T., GÜMRÜ S., GÜMRÜ TARÇIN B.
  • Publication
    Evaluation of cone beam computed tomography referral profile: Retrospective study in a Turkish paediatric subpopulation
    (ARIESDUE SRL, 2021) GÜMRÜ TARÇIN, BİRSAY; Gumru, B.; Guldali, M.; Tarcin, B.; Idman, E.; Peker, M. Sertac
    Aim Increasing use of cone beam computed tomography (CBCT) for dentomaxillofacial diagnosis raises concerns about radiation dose which is known to be higher compared to conventional dental imaging methods. This retrospective study investigated the CBCT referrals in a Turkish paediatric subpopulation in terms of referring department, field of view (FOV), and findings. Materials and methods A total of 8,880 CBCT images were reviewed retrospectively and images of paediatric patients (<= 14 years old) were selected. In paediatric patients; data related to patient age and gender, referring department, FOV, region of interest for localised applications, and reason for CBCT referral were recorded. FOVs of CBCT scans were classified as face, jaws (maxilla and mandible), maxilla, mandible, and tooth. CBCT indications were categorised based upon an adaptation of the European DIMITRA (dentomaxillofacial paediatric imaging: an investigation towards low-dose radiation induced risks) multicenter and multidisciplinary project recommendations as impacted teeth, trauma, orofacial clefts, dental anomalies, bone pathology, syndromes, and other. Patients undergoing consecutive CBCT examinations for follow-up were also recorded. In order to record the incidental findings noticed in the CBCT evaluation, the radiological report prepared by the radiologist was used. The results were analysed statistically with a significance level set at p<0.05. Results Four hundred forty-nine of the 8880 CBCT scans were taken from paediatric patients under the age of 14, representing approximately 5% of all scans. Most of the referrals were from Department of Paediatric Dentistry (36.3%), followed by Department of Orthodontics (25.6%). The most frequently imaged region was the maxilla (33.4%), followed by the face (20.5%). The most common region of interest for localised applications was the maxillary canine/incisor region (85.55%). The most common indication was impacted teeth (41.4%) followed by bone pathology (31%) and dental anomalies (29.6%); 11.6% of the patients underwent follow-up CBCT examinations especially for orofacial clefts and syndromes. Conclusions This retrospective study investigating CBCT indications in a Turkish paediatric subpopulation and comparing existing applications with DIMITRA project recommendations can guide dental professionals in referring paediatric patients for CBCT.
  • PublicationOpen Access
    Solid Organ Transplant Candidates and Recipients: Dentists’ Perspective
    (2021-06-15) GÜMRÜ TARÇIN, BİRSAY; Gümrü, Birsay; Tarçin, Bilge