Person: VELİOĞLU, ARZU
Loading...
Email Address
Birth Date
Research Projects
Organizational Units
Job Title
Last Name
VELİOĞLU
First Name
ARZU
Name
78 results
Search Results
Now showing 1 - 10 of 78
Publication Metadata only C3 Glomerulopatisi(Güneş Kitabevi, 2022-08-01) TUĞCU, MURAT; VELİOĞLU, ARZU; Tuğcu M., Velioğlu A.Publication Metadata only Böbrek nakli adaylarında kırılganlık tanımlanması ve gözlemi(2021-10-13) ŞANAL TOPRAK, CANAN; BARUTÇU ATAŞ, DİLEK; TUFAN ÇİNÇİN, ASLI; VELİOĞLU, ARZU; TUĞLULAR, ZÜBEYDE SERHAN; Rustamzade A., BARUTÇU ATAŞ D., ŞANAL TOPRAK C., TUFAN ÇİNÇİN A., VELİOĞLU A., TUĞLULAR Z. S.Publication Metadata only Hemodiyaliz ve Periton Diyalizi Tedavisi Alan Hastalarda Uzun Dönemde Gelişen Kognitif ve Fiziksel Bozukluklar.(2021-10-13) BARUTÇU ATAŞ, DİLEK; VELİOĞLU, ARZU; ARIKAN, İZZET HAKKI; AŞICIOĞLU, EBRU; Süleymanova G., BARUTÇU ATAŞ D., TUĞCU M., VELİOĞLU A., ARIKAN İ. H., AŞICIOĞLU E.Giriş: Diyaliz hastalarında uzun dönemde gelişen kognitif ve fiziksel fonksiyonlardaki gerileme yaşam kalitesinde bozulma ve artmış mortalite ile ilişkilidir. Bu çalışmada hemodiyaliz ve periton diyalizi tedavisi alan hastalarda kognitif ve fiziksel bozuklukları belirleyerek karşılaştırmayı hedefledik. Yöntemler: Çalışmamıza 20 periton diyalizi (PD) ve 24 hemodiyaliz (HD) hastası dahil edildi. Hastaların kognitif bozukluklarını değerlendirmek için MoCA (Montreal Kognitif Değerlendirme) ve MMSE (Mini Mental Durum Değerlendirme) testleri, fiziksel bozuklukları değerlendirmek için Lawton ve Brody EGYA(Enstrümental Günlük Yaşam Aktivitesi) ile Katz GYA (Günlük Yaşam Aktivitesi) testleri kullanılmıştır. Hastaların medikal özgeçmişi, kronik hastalıkları, diyalize başlama tarihleri sorgulandı. Laboratuvar verileri kaydedildi. Bulgular:HD tedavisi alan hastalar daha yaşlıydı (55.3±15.3 vs 48.2±10.1 yıl p=0.036). Grupların demografik ve laboratuvar verileri Tablo 1’de gösterilmiştir. PD hastalarının MoCA (21.9±6.0 vs 16.6±7.1, p=0,008).Lawton ve Brody EGYA (7.6±1.6 vs 6.4±2.4, p=0.025) ve Katz GYA(6.0±0.0 vs 5.5±1.0, p=0.018) skorları HD hastalarından yüksekti. Gruplarının kognitif ve fiziksel fonksiyonları Tablo 2’de karşılaştırılmıştır. Korelasyon analizinde yaş ile MoCA (r= -0.482, p= 0.001), MMSE (r= -0.462, p= 0.002) ve EGYA (r= -0.549, p= 0.001) arasında negatif korelasyon mevcuttu. Sonuç: Bu çalışmada her iki grupta da hastaların önemli bir kısmında kognitif ve fiziksel fonksiyonlarda bozulma mevcuttu. Ancak PD grubunda hastaların kognitif ve fiziksel fonksiyonlarının HD grubuna nazaran daha iyi korunduğunu gösterdik. İlerleyen dönemlerde diyaliz hastalarında gelişecek bu bozuklukların önlenmesi için hastaların yakından takip edilmesi gerekmektedir.Publication Metadata only Cardiac Risk Assessment in Kidney Transplant Candidates: Clinical Usefulness of Different Guidelines(ELSEVIER SCIENCE INC, 2019) ÇİNÇİN, AHMET ALTUĞ; Mehdiyev, S.; Velioglu, A.; Arikan, H.; Asicioglu, E.; Cincin, A.; Demirbas, T.; Tinay, I; Ozener, C.; Tuglular, S.Although cardiovascular (CV) assessment is recommended to minimize perioperative risk in all potential kidney transplant recipients, the utility and reliability of various assessment methods are not well established. In this study, we investigated the CV evaluations and outcomes of standardized CV assessment protocols (Lisbon and American Society of Transplantation [AST]) in potential kidney transplant recipients. Data were analyzed for 266 end-stage renal disease patients (mean age 45.4 +/- 13 years, female-to-male ratio 126:140) accepted for kidney transplantation wait-listing. Patients were classified as low and high cardiac risk according to their first cardiac evaluation. Major cardiovascular events (CVEs) and deaths were recorded. At the end of follow-up (median 639 days), 72 (27.1%) patients underwent kidney transplantation. A total of 49 patients (18.4%) had CVEs and 42 (15.8%) patients died. Being over 45 years of age and having dialysis vintage over 1 year were found to be independent risk factors for CVEs. Forty-eight out of 60 high-risk patients evaluated with noninvasive tests had negative results. Twelve out of these 48 patients had a CVE in due course. Among 10 patients who underwent coronary angiography, 1 had a CVE and 1 died. The sensitivity and specificity of the AST guidelines (area under the curve = 0.647, P = .005, sensitivity 83%, specificity 54%) were higher than Lisbon. In conclusion, the predictive risk factors for CVEs were age over 45 years and dialysis vintage over a year. Our results also suggest that exercise electrocardiography and myocardial perfusion scintigraphy for cardiac evaluation are less sensitive in CVE prediction. We recommend clinicians to use the AST guidelines and to prioritize coronary angiography in pretransplant CV assessment.Publication Open Access The 3-step model of informed consent for living kidney donation: A proposal on behalf of the DESCaRTES working group of the european renal association(2023-01-01) VELİOĞLU, ARZU; Grossi A. A., Sever M. S., Hellemans R., Mariat C., Crespo M., Watschinger B., Peruzzi L., Demir E., VELİOĞLU A., Gandolfini I., et al.Living donation challenges the ethical principle of non-maleficence in that it exposes healthy persons to risks for the benefit of someone else. This makes safety, informed consent (IC) and education a priority. Living kidney donation has multiple benefits for the potential donor, but there are also several known short- and long-term risks. Although complete standardization of IC is likely to be unattainable, studies have emphasized the need for a standardized IC process to enable equitable educational and decision-making prospects for the prevention of inequities across transplant centers. Based on the Three-Talk Model of shared decision-making by Elwyn et al., we propose a model, named 3-Step (S) Model, where each step coincides with the three ideal timings of the process leading the living donor to the decision to pursue living donation: prior to the need for kidney replacement therapy (team talk); at the local nephrology unit or transplant center, with transplant clinicians and surgeons prior to evaluations start (option talk); and throughout evaluation, after having learned about the different aspects of donation, especially if there are second thoughts or doubts (decision talk). Based on the 3-S Model, to deliver conceptual and practical guidance to nephrologists and transplant clinicians, we provide recommendations for standardization of the timing, content, modalities for communicating risks and assessment of understanding prior to donation. The 3-S Model successfully allows an integration between standardization and individualization of IC, enabling a person-centered approach to potential donors. Studies will assess the effectiveness of the 3-S Model in kidney transplant clinical practice.Publication Open Access COVID-19 in hospitalized lung and non-lung solid organ transplant recipients: A comparative analysis from a multicenter study(WILEY, 2021-08) VELİOĞLU, ARZU; Heldman, Madeleine R.; Kates, Olivia S.; Safa, Kassem; Kotton, Camille N.; Georgia, Sarah J.; Steinbrink, Julie M.; Alexander, Barbara D.; Hemmersbach-Miller, Marion; Blumberg, Emily A.; Crespo, Maria M.; Multani, Ashrit; Lewis, Angelica, V; Beaird, Omer Eugene; Haydel, Brandy; La Hoz, Ricardo M.; Moni, Lisset; Condor, Yesabeli; Flores, Sandra; Munoz, Carlos G.; Guitierrez, Juan; Diaz, Esther, I; Diaz, Daniela; Vianna, Rodrigo; Guerra, Giselle; Loebe, Matthias; Rakita, Robert M.; Malinis, Maricar; Azar, Marwan M.; Hemmige, Vagish; McCort, Margaret E.; Chaudhry, Zohra S.; Singh, Pooja; Hughes, Kailey; Velioglu, Arzu; Yabu, Julie M.; Morillis, Jose A.; Mehta, Sapna A.; Tanna, Sajal D.; Ison, Michael G.; Tomic, Rade; Derenge, Ariella Candace; van Duin, David; Maximin, Adrienne; Gilbert, Carlene; Goldman, Jason D.; Sehgal, Sameep; Weisshaar, Dana; Girgis, Reda E.; Nelson, Joanna; Lease, Erika D.; Limaye, Ajit P.; Fisher, Cynthia E.Lung transplant recipients (LTR) with coronavirus disease 2019 (COVID-19) may have higher mortality than non-lung solid organ transplant recipients (SOTR), but direct comparisons are limited. Risk factors for mortality specifically in LTR have not been explored. We performed a multicenter cohort study of adult SOTR with COVID-19 to compare mortality by 28 days between hospitalized LTR and non-lung SOTR. Multivariable logistic regression models were used to assess comorbidity-adjusted mortality among LTR vs. non-lung SOTR and to determine risk factors for death in LTR. Of 1,616 SOTR with COVID-19, 1,081 (66%) were hospitalized including 120/159 (75%) LTR and 961/1457 (66%) non-lung SOTR (p = .02). Mortality was higher among LTR compared to non-lung SOTR (24% vs. 16%, respectively, p = .032), and lung transplant was independently associated with death after adjusting for age and comorbidities (aOR 1.7, 95% CI 1.0-2.6, p = .04). Among LTR, chronic lung allograft dysfunction (aOR 3.3, 95% CI 1.0-11.3, p = .05) was the only independent risk factor for mortality and age >65 years, heart failure and obesity were not independently associated with death. Among SOTR hospitalized for COVID-19, LTR had higher mortality than non-lung SOTR. In LTR, chronic allograft dysfunction was independently associated with mortality.Publication Open Access Pseudoporphyria in a Peritoneal Dialysis Patient(MULTIMED INC, 2015-03) VELİOĞLU, ARZU; Velioglu, Arzu; Ergun, Tulin; Ozener, CetinPublication Open Access Low bone density, vertebral fracture and FRAX score in kidney transplant recipients: A cross-sectional cohort study(PUBLIC LIBRARY SCIENCE, 2021-04-30) VELİOĞLU, ARZU; Velioglu, Arzu; Kaya, Burcu; Aykent, Basar; Ozkan, Bige; Karapinar, Melis Sevil; Arikan, Hakki; Asicioglu, Ebru; Bugdayci, Onur; Yavuz, Dilek Gogas; Tuglular, SerhanBackground Kidney transplantation (KT) recipients are at increased risk of low bone density (LBD) and fractures. In this retrospective study, we investigated bone mineral density (BMD), vertebral fractures, calculated risk for major osteoporotic fractures (MOF), and hip fractures in the KT recipients. Patients-method Patients who completed at least one year after KT were included in the analysis. Demographic, clinical, and laboratory data were recorded. Measurements of BMD were performed by dual-energy X-ray absorptiometry. Vertebral fractures were assessed using semi-quantitative criteria with conventional radiography. The ten-year risk for MOF and hip fracture were calculated using the FRAX@ tool with BMD. Results One hundred fifty-three KT recipients were included in the study. The population included 77 women. The mean age at evaluation was 46,511,9 years. Seventy-eight (50.9%) patients had normal femoral neck BMD while osteoporosis and osteopenia at the femoral neck were present in 12 (7.8%) and 63 (41.1%) of the patients, respectively. Age at evaluation was the risk factor for LBD (OR 1.057; 95% CI 1.024-1.091; p = 0.001). In female KT recipients, LBD was principally affected by menopausal status whereas in males, mammalian target of rapamycin (mTOR) inhibitor use and lower BMI levels were the risk factors. The prevalent vertebral fracture was found in 43.4% of patients. In multivariate analysis, only steroid use (OR 0.121; 95% CI 0.015-0.988; p = 0.049) was found to be associated with prevalent fracture. Among all KT recipients, 1.9% had a high MOF probability (>= 20% risk of fracture), and 23.5% had high hip fracture probability (>= 3% risk of hip fracture) according to FRAX. Conclusion Exploring the prevalence of LBD and vertebral fracture and the risk factors would help clinicians to modify long-term follow-up strategies. Furthermore, the high hip fracture risk probability in our cohort suggested that there is a need for longitudinal studies to confirm the validity of the FRAX tool in the transplant population.Publication Metadata only Waist circumference is associated with carotid intima media thickness in peritoneal dialysis patients(SPRINGER, 2013) VELİOĞLU, ARZU; Asicioglu, Ebru; Kahveci, Arzu; Arikan, Hakki; Koc, Mehmet; Tuglular, Serhan; Ozener, Cetin IshakAtherosclerosis is responsible for the high mortality rate in end-stage renal disease patients. Defining risk factors for atherosclerosis may lead to reduction in cardiovascular disease through modification of these factors. Peritoneal dialysis (PD) patients are subjected to high glucose loads on a daily basis, which results in considerable weight gain and an increase in waist circumference (WC). WC as an indicator of abdominal obesity is a risk factor for atherosclerosis in the general population. Carotid artery intima media thickness (CIMT) measurement is a reliable method for the detection of early atherosclerosis. The aim of this study was to investigate the relationship between WC and CIMT and to define risk factors associated with CIMT in PD patients. Fifty-five PD patients and 40 healthy controls were included. Atherosclerosis was assessed using measurement of CIMT. Fasting blood was collected for analysis. Anthropometric parameters (age, weight, BMI, and WC) were measured. Peritoneal dialysis patients had higher WC (93.9 +/- A 1.7 vs. 87.3 +/- A 1.2 cm, p < 0.05) and CIMT (0.70 +/- A 0.02 vs. 0.57 +/- A 0.01 mm, p < 0.01) than the control group. On univariate analysis, age, WC, plaque formation, and D/P creatinine were positively correlated with CIMT, whereas residual renal function, albumin, ultrafiltration volume, and D/D0 glucose were negatively correlated. On multivariate analysis, only age, WC, and plaque formation showed correlation (p < 0.001). Carotid artery intima media thickness is associated with age, plaque formation, and WC in PD patients. WC measurement is a simple, inexpensive, reproducible, and reliable method of evaluating atherosclerosis risk in PD patients and should be assessed at every visit. Appropriate counsel should be provided to patients with greater WC who are deemed to be at risk for atherosclerosis.Publication Metadata only Sepsiste serum laktat yüksekliği-sidemi ilişkisinin böbrek fonksiyonları penceresinden incelenmesi(2022-12-08) TUĞCU, MURAT; AŞICIOĞLU, EBRU; ARIKAN, İZZET HAKKI; BARUTÇU ATAŞ, DİLEK; TUĞLULAR, ZÜBEYDE SERHAN; VELİOĞLU, ARZU; Karadağ H., Berke Menteşe İ., Barutçu Ataş D., Tuğcu M., Aşıcıoğlu E., Velioğlu A., Tuğlular Z. S. , Arıkan İ. H.