Person: TOPKAR, OSMAN MERT
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TOPKAR
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OSMAN MERT
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Publication Metadata only Pediatrik radius diafiz kırıklarının intramedüller tel ile fiksasyonunda, dorsal veya lateral giriş yeri fonksiyonel sonuçları ve komplikasyon oranını değiştirir mi(2019-11-22) AKGÜLLE, AHMET HAMDİ; TOPKAR, OSMAN MERT; ŞİRİN, EVRİM; AKGÜLLE A. H., ONAY T., İĞREK S., KESİMER M. D., TOPKAR O. M., ŞİRİN E.Amaç: Çocuk radius diafiz kırıkları cerrahi tedavisinde intrameduller tel ile fiksasyon en sık kullanılan yöntemdir. Tel girişi dorsal ve lateralden yapılabilmektedir. Çalışmanın amacı, pediatrik radius diafiz kırıklarında dorsal giriş ya da lateral girişli intrameduller fiksasyon yapılmış olguları fonksiyonel sonuç ve komplikasyon oranları açısından karşılaştırmaktı. Yöntem: 2014-2018 yılları arasında tek bir merkezde pediatrik radius diafiz kırığı nedeniyle cerrahi uygulanmış olan hastalar retrospektif olarak incelendi. İntramedüller yöntemle tedavi edilmemiş, dosya ve takipleri yetersiz ve patolojik kırığı olan hastalar çalışmadan çıkarıldı. Dorsal giriş yapılan 19 (Grup A), lateral giriş yapılan (Grup B) 18, toplam 37 hasta çalışmaya alındı. Hastaların; yaş, kırıktan ameliyata kadar geçen süre, kaynama (pin çıkarma) süreleri, açık veya kapalı cerrahi uygulanması, perop ve geç postop komplikasyonları ile fonksiyonel skorları kaydedildi. Radius alt uçta kırık gelişmesi major komplikasyon, el bilekte hafif ağrı ve hareket kısıtlılığı minör komplikasyon olarak kabul edildi. Fonksiyonel değerlendirmede Childrens Hospital of Philadelphia Önkol Kırık Fonksiyon Sınıflaması kullanıldı. Veriler istatistiksel olarak analiz edildi. Bulgular: Hastaların ortalama yaşı 10,5 yıl ve ortalama takip süresi 37 ay olarak bulundu. Tüm kırıklar ortalama 47 günde kaynadı. Grup A’da 2, Grup B’de 1 hastada giriş sırasında radius alt uçta kırık oluştu. Grup A’da 1 hastada, Grup B’de 3 hastada minör komplikasyon tespit edildi. 30 hastada (%81,1) mükemmel, 4 hastada (%10,8) orta ve 3 hastada (%8,1) kötü sonuç elde edildi. İki grup arasında, komplikasyon gelişimi ve fonksiyonel skor açısından istatistiksel anlamlı fark saptanmadı (p>0.05). Çıkarımlar: Pediatrik radius diafiz kırıklarının intramedüller fiksasyonunda, tel giriş yeri ile komplikasyonlar ve fonksiyonel sonuç arasında bir ilişki bulunamamıştır. Her iki giriş noktasında benzer sonuçlar elde edilebilmektedir. Geniş serilerle prospektif olarak yapılacak çalışmalar daha yol gösterici olacaktır.Publication Metadata only Osteoid Osteoma of Distal Phalanx of Toe: A Rare Cause of Foot Pain(2014) EROL, BÜLENT; Başar, Hakan; Topkar, Osman Mert; Erol, BülentOsteoid osteoma is an uncommon benign tumor and causes severe pain, being worse at night, that responds dramatically to nonsteroidal anti-inflammatory medications. An osteoid osteoma of the toe is very rare and arising in a pedal phalanx may be difficult to diagnose. A 34-year-old male has local swelling and tenderness but there were no hyperemia, temperature increase, or clubbing. There was a 2-month history of antibiotic treatment with suspicion of soft tissue infection in another clinic. The osteoid osteoma was completely excised by curettage and nidus removal with open surgical technique. The patient was followed up for 63 months with annual clinical and radiographic evaluations. There was no relapse of the pain and no residual recurrent tumour. Osteoid osteoma may be difficult to distinguish from chronic infection or myxedema. The patients may be taken for unnecessary treatment. The aim of the treatment for osteoid osteoma is to remove entire nidus by open surgical excision or by percutaneous procedures such as percutaneous radiofrequency and laser ablation. Osteoid osteomas having radiologic and clinical features other than classical presentation of osteoid osteoma are called atypical osteoid osteomas. Atypical localized osteoid osteomas can be easily misdiagnosed and treatment is often complicated.Publication Open Access Management of orthopedic oncology patients during coronavirus pandemic(WILEY, 2020-09) EROL, BÜLENT; Sahbat, Yavuz; Buyuktopcu, Omer; Topkar, Osman Mert; Erol, BulentThe new measures implemented in hospitals also altered the operation of orthopedics and traumatology departments. The main purpose of this article is to discuss how orthopedic oncology clinics should be organized during the pandemic and to present the process management scheme for patients requiring orthopedic surgery, including trauma surgery, from diagnosis to treatment, together with our experiences. Instead of thinking about the global emergence of the epidemic, it is time to act decisively. At first glance, the coronavirus disease 2019 (COVID-19) pandemic and orthopedics may seem to be unrelated disciplines, but the provision of healthcare services to patients who require them proves that these two fields are parts of the same whole. Our experiences in treating neutropenic, lymphocytopenic, and chemotherapy patients seem to have proven beneficial during this process. We operated on 10 biopsy patients, 15 primary bone sarcomas, 9 soft tissue sarcomas, and 82 trauma patients within this time frame. Only three patients were suspected to have COVID-19 before admission. The early identification, strict isolation, and effective treatment of these patients prevented any nosocomial infections and disease-related comorbidities. This success is the result of the multidisciplinary cooperation of the Ministry of Health, our hospital, and our clinic.Publication Metadata only An Algorithm For Soft Tissue Reconstruction Followıng Standard Or Complex Resections Performed In Initial Or Revision Surgery Of Primary Or Recurrent Bone And Soft Tissue Sarcomas(2018-05-13) EROL, BÜLENT; DURMUŞ KOCAASLAN, FATMA NİHAL; TOPKAR, OSMAN MERT; EROL B., ÇAVUŞ ÖZKAN M., DURMUŞ KOCAASLAN F. N., TOPKAR O. M., BAYSAL Ö., BAYKAN S. E.Publication Metadata only Dysosteosclerosis is also caused by TNFRSF11A mutation(NATURE PUBLISHING GROUP, 2018) ELÇİOĞLU, HURİYE NURSEL; Guo, Long; Elcioglu, Nursel H.; Karalar, Ozge K.; Topkar, Mert O.; Wang, Zheng; Sakamoto, Yuma; Matsumoto, Naomichi; Miyake, Noriko; Nishimura, Gen; Ikegawa, ShiroDysosteosclerosis (DOS) is a form of sclerosing bone disease characterized by irregular osteosclerosis and platyspondyly. Its mode of inheritance is autosomal recessive. SLC29A3 mutations have been reported as the causal gene in two DOS families, however, genetic heterogeneity has been suggested. By whole-exome sequencing in a Turkish patient with DOS, we found a novel splice-site mutation in TNFRSF11A. TNFRSF11A mutations have previously been reported in two autosomal dominant diseases (osteolysis, familial expansile and Paget disease of bone 2, early-onset) and an autosomal recessive disease (osteopetrosis, autosomal recessive 7). The biallelic mutation, c. 616+3A>G, identified in our study was located in the splice donor site of intron 6 of TNFRSF11A. Exon trapping assay indicated the mutation caused skipping of exon 6, which was predicted to induce a frame-shift and an early termination codon in all known alternative transcript variants of TNFRSF11A. The predicted effect of the mutation for the isoforms was different from those of the previously reported mutations, which could explain the difference of their phenotypes. Thus, our study identified the second disease gene for DOS. TNFRSF11A isoforms may have the different roles in skeletal development and metabolism.Publication Metadata only Dorsal or Lateral Approach for Intramedullary Nailing Using Kirschner Wire in Pediatric Radius Diaphyseal Fractures: Does it really matter?(SPRINGER HEIDELBERG, 2021) AKGÜLLE, AHMET HAMDİ; Akgulle, Ahmet Hamdi; Onay, Tolga; Igrek, Servet; Kesimer, Mehmet Deniz; Topkar, Osman Mert; Sirin, EvrimBackground Intramedullary nailing is the most preferred fixation method for diaphyseal radius and ulna fractures in the young age group. The aim of this study was to compare the dorsal and lateral entry points in the context of entry site-related complications, fracture union and functional results. Methods This retrospective comparative study included pediatric patients who underwent surgery for isolated diaphyseal radius or both bone forearm fractures with intramedullary nailing using Kirschner wire between January 2013 and January 2019. K-wire was introduced from the distal radius through dorsal entry (Group A) in 19 patients and lateral entry (Group B) in 18 patients. The mean follow-up was 37 months. Complications were noted and functional outcomes were evaluated according to the CHOP criteria. Results All fractures were healed. The functional results were determined to be excellent for 30, fair for 4, and poor for 3 patients. The overall complication rate was 18.9%, including distal radius fracture, mild pain in the wrist, and minor loss in ROM. No statistically significant differences were determined between the groups in respect of functional results and complication rates. Conclusion Good functional results and similar complication rates can be obtained with both dorsal and lateral entry approaches. Stainless steel K-wire is an inexpensive intramedullary fixation implant option, which provides strong stabilization. Distal radius fracture is a newly reported complication for forearm intramedullary nailing. Leaving the implant out of the skin seems safe with the benefit of avoiding a further surgical intervention to extract the implant.Publication Open Access Acromioclavicular joint injuries: diagnosis, classification and ligamentoplasty procedures(2018-07) TOPKAR, OSMAN MERT; Sirin, Evrim; Aydin, Nuri; Mert Topkar, OsmanAcromioclavicular (AC) joint injury is a frequent diagnosis after an acute shoulder trauma – often found among athletes and people involved in contact sports. This injury occurs five times more frequently in men than in women, with the highest incidence in the 20- to 30-year-old age group. Patients usually complain of pain and tenderness over the shoulder, particularly over the AC joint. Depending on the degree of injury, the clavicle may become prominent on the injured site. The original classification was described by Rockwood and Green according to the injured ligament complex and degree and direction of clavicular displacement. Many surgical procedures have been described; among these are screws, plates, muscle transfer, ligamentoplasty procedures and ligament reconstruction using either autograft or allografts. With the advancement of shoulder arthroscopy, surgeons are much more capable of performing mini-open or arthroscopically-assisted procedures, allowing patients an earlier return to their daily living activities. However, the results of conventional open techniques are still comparable. The introduction of new arthroscopic equipment provides a great variety of surgical procedures, though every new technique has its own advantages and pitfalls. Currently there is no gold standard for the surgical treatment of any type of AC injury, though it should be remembered that whenever an arthroscopic technique is chosen, the surgeon’s expertise is likely to be the most significant factor affecting outcome. Cite this article: EFORT Open Rev 2018;3:426-433. DOI: 10.1302/2058-5241.3.170027Publication Open Access Reconstruction of Advanced Periacetabular Metastatic Lesions with Modified Harrington Procedure(2017-05-01) TOPKAR, OSMAN MERT; ŞİRİN, EVRİM; EROL, BÜLENT; AYDEMİR A. N. , TOPKAR O. M. , TOKYAY A., ŞİRİN E., EROL B.Objective: The purpose of this study was to assess the outcomes of patients who had been treated by a modified Harrington procedure for advanced periacetabular metastases. Methods: Between 2006 and 2013, 16 patients with a mean age of 57 years (range: 28–73 years) were treated using a modified Harrington technique. Extensive (class II/III) periacetabular defects were due to metastatic carcinoma or multiple myeloma. Surgical procedure included total hip replacement and acetabular reconstruction using threaded pins, cemented acetabular reinforcement ring, and/or polyethylene cup. Results: All patients improved in regard to pain and walking ability. Mean preoperative and postoperative Musculoskeletal Tumour Society (MSTS) functional scores were 52.8% (range: 33.3–73.3%) and 72% (range: 56.6–90%), respectively (p<0.05). There were 5 (31%) early or late complications requiring additional surgery. Implant survival was 75% and 37.5% at 12 and 18 months, respectively. Mean survival of the patients was 21 months (range: <1–6 years). Six remained alive, with a mean survival of 27 months (range: 18 months to 5 years). Conclusion: This modified Harrington procedure can be used for reconstruction of advanced periacetabular metastatic lesions. Keywords: Harrington procedure; periacetabular metastasis; surgical treatment. Level of Evidence: Level IV - Case series, Therapeutic study.Publication Metadata only A treatment strategy for proximal femoral benign bone lesions in children and recommended surgical procedures: retrospective analysis of 62 patients(SPRINGER, 2016) EROL, BÜLENT; Erol, Bulent; Topkar, Mert Osman; Aydemir, Ahmet Nadir; Okay, Erhan; Caliskan, Emrah; Sofulu, OmerWe aimed to develop a surgical treatment strategy for benign bone lesions of the proximal femur based upon retrospective review of our data in 62 children. Sixty-two children [38 male, 24 female; median age 9 years (range 5-18 years)] with proximal femoral benign bone lesions were surgically treated between 2005 and 2013. Histopathological diagnoses were simple (31) or aneurysmal (27) bone cysts, and nonossifying fibromas (4). The pathological fracture rate was 77.4 %. Surgical treatment was determined due to four criteria, including patient's skeletal maturity, localization and initial diagnosis of lesion, and amount of bone loss in the femoral neck and lateral proximal femur. Surgical procedure consisted of biopsy, curettage, bone grafting, and internal fixation when required. The median follow-up was 45 months (range 25-89 months). Complete clinical recovery was achieved in 56 (90.3 %) patients between 4 and 8 months postoperatively; full weight-bearing and mobilization, without pain and limping, was possible. The median preoperative and postoperative last follow-up Musculoskeletal Tumor Society (MSTS) scores were 13.3 % (range 10-23.3 %) and 96.6 % (range 90-100 %), respectively (p < 0.0001). The pathological fractures were healed in 10 weeks on average (range 8-12 weeks). Fifty-seven (92 %) patients demonstrated complete or significant partial radiographic healing between 5 and 7 months that maintained throughout follow-up. Local recurrence was not observed, and only 1 (1.6 %) patient required reoperation for partial cyst healing. There were 5 (8 %) complications, 1 (1.6 %) of which required reoperation. This treatment strategy can provide good local control and excellent functional and radiological results in the management of benign bone lesions of the proximal femur in children.Publication Metadata only Comparison of treatment of oblique and spiral metacarpal and phalangeal fractures with mini plate plus screw or screw only(SPRINGER, 2015) EROL, BÜLENT; Basar, Hakan; Basar, Betul; Basci, Onur; Topkar, Osman Mert; Erol, Bulent; Tetik, CihangirWe aimed to compare results of treatment of oblique-spiral metacarpal and phalangeal fractures with screw only or mini plate plus screw, respectively. A total of 43 patients who were operated with a diagnosis of displaced, irreducible, unstable, rotational oblique-spiral metacarpal and proximal phalangeal fracture between 2007 and 2010 were included in this study. The mean age of patients with a phalangeal fracture was 33.8 years (range 20-50 years; 4 females, 18 males), and the mean age of patients with a metacarpal fracture was 29.6 years (range 18-45 years; 3 females, 18 males). Mini plate plus screw or screw only was used for internal fixation of these fractures. The patients were followed up for 19.2 +/- A 5.4 months in the phalangeal fracture group and 20.9 +/- A 7.3 months in metacarpal fracture group. Of the metacarpal fractures, 14 were oblique and 10 spiral, whereas 14 of the phalangeal fractures were oblique and 8 spiral. The patients were evaluated according to total range of motion of the finger, grasping strength and Q-DASH score. For patients treated with mini plate plus screw after metacarpal and phalangeal fractures, the time to return to work was significantly shorter in comparison to patients treated with screws only. There was no significant difference between patients with metacarpal fractures treated with mini plate plus screw and patients treated with screw only in terms of total range of motion and Q-DASH results at last on control examination, while results of patients with phalangeal fractures treated with screw only were significantly better. There was no significant difference between these two treatments in phalangeal fractures in terms of grasping strength of the finger in early (1st month) and late (last control examination), whereas patients with metacarpal fractures treated with mini plate plus screw reached higher grasping strength earlier. Treatment with mini plate plus screw should be avoided in spiral and oblique phalangeal fractures, and fixation should be done with screw only with a short surgical incision and dissection. On the other hand, treatment with mini plate plus screw should be preferred in patients with spiral and oblique metacarpal fractures, especially in those who work in occupations requiring higher physical strength.