Person: AKVARDAR, YILDIZ
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AKVARDAR
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YILDIZ
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Publication Metadata only The role of dopamine(2) receptor gene and personality characteristics in alcohol dependence in Turkish population(CUMHURIYET UNIV TIP FAK PSIKIYATRI ANABILIM DALI, 2014) AKVARDAR, YILDIZ; Dalmis, Arzu; Akvardar, Yildiz; Eresen, Cigdem; Kizildag, Sefa; Akpulat, Ugur; Yildirimcan, Sebnem; Arkar, Haluk; Akdede, Berna Binnur; Alptekin, KoksalObjective: Focusing on dopaminergic system, which is regarded to be responsible for alcohol dependence in many studies on animals and human beings, it is aimed to investigate Taql A and 8 allel polymorphisms of dopamine 2 receptor and personality characteristics in alcohol dependents and the relationship between these two parameters. Methods: In this study 64 alcohol dependent patients (3 females, 61 males) diagnosed according to DSM-IV diagnosis criteria, and 54 healthy subjects (8 females, 46 males) who themselves or whose first or second degree relatives had no alcohol dependence history were included. In order to determine their Taql A and 8 alleles, blood samples were drawn from the participants, and then they were applied Temperament and Character Inventory and Michigan Alcoholism Screening Test. Results: Subjects with and without alcohol dependence revealed no significant difference as regards the frequency of Taql A1 and B2 minor allel polymorphisms of DRD2 gene. It was also determined that the alcohol dependents had significantly higher scores in novelty seeking and harm avoidance dimensions, and lower scores in self directedness and cooperativeness dimensions than the controls. In alcohol dependents, no association was determined between the personality characteristics and Taql A1 and B2 minor allel polymorphisms. Conclusion: Not only one gene, but also several other minor genes in addition to personality characteristics and environment may play a role in vulnerability to alcohol dependence. In alcohol dependents, high novelty seeking is associated with the increase in impulsive behavior, and may be important for the onset of alcohol taking behavior. High level of harm avoidance may lead to taking alcohol continuously in order to deal with stress.Publication Metadata only Bilir kişi raporu(2020-09-01) MİDİ, İPEK; AKVARDAR, YILDIZ; İNANICI, MEHMET AKİF; İŞAK, BARIŞ; MİDİ İ., AKVARDAR Y., TOPÇUOĞLU V., İNANICI M. A., İŞAK B.Publication Open Access Impact of COVID-19 on the Life of Higher-Education Students in Istanbul: Relationship Between Social Support, Health-Risk Behaviors, and Mental/Academic Well-Being(AVES, 2021-11-01) YORGUNER, NEŞE; Bulut, Necati Serkut; Yorguner, Nese; Akvardar, YildizObjective:This study aimed to draw a general picture of the impact of the coronavirus disease 2019 (COVID-19) pandemic on the life of higher-education students in Istanbul, with specific emphasis on the relationship between students' social support systems, health-risk behaviors, and mental/academic well-being. Methods: A total of 2583 higher-education students from different fields of study participated in an online survey gathering information from several domains, including available social networks, support-seeking attitudes, substance use patterns, physical activity levels, academic stress, academic satisfaction, and psychological well-being during the pandemic. Results: Our findings pointed to major changes in students' life circumstances and daily routines during COVID-19, including a significant decrease in contact with friends, over-all substance use, and physical activity as well as high levels of depression, academic stress, and academic dissatisfaction. Depressive symptoms were significantly predicted by the loneliness score (OR= 2.08, 95% CI = 1.88-2.29), female gender (OR =1.65, 95% CI =1.21-2.24), frequency of binge drinking (OR =1.4, 95% CI = 1.06-1.86), and level of academic stress (OR =1.15, 95% CI =1.1-1.19), whereas the number of people to easily borrow money from was found to be a protective factor against depression (OR =0.95, 95% CI =0.92-0.99). Conclusion: Our results highlight the need for higher-education institutions to take the appropriate social and mental health interventions, tailored to fit the specific requirements of the COVID-19-related measures.Publication Open Access Domestic Violence Among Women Attending to Psychiatric Outpatient Clinic(AVES, 2018-03-19) YORGUNER, NEŞE; Kurt, Emel; Yorguner Kupeli, Nese; Sonmez, Ekin; Bulut, Necati Serkut; Akvardar, YildizObjective: Domestic violence (DV) is defined as all kinds of abusive behaviors between spouses or relatives living in the same house. Domestic violence is most commonly directed towards women and children. This study aims to review the extent of domestic violence among women consulting to psychiatric outpatient clinic, and to identify its relation with sociodemographic risk factors and psychological symptoms. Method: Self-reported Domestic Violence Questionnaire and Symptom Checklist-90-R (SCL-90-R) information was collected from women who admitted to psychiatric outpatient clinic at Marmara University Research and Educational Hospital, and accepted to participate in the study. Results: 300 women participated in the study. Mean age of participants was 36.24 +/- 10.88, 75.7% of them were married, and mostly live within nuclear families. 70.1% of the participants reported verbal violence, and 49.0% reported physical violence. 65.3% of those who have experienced verbal violence have also experienced physical violence. 26.1% of them reported as not having experienced domestic violence before. The nature and extent of domestic violence, women's attitudes towards it, and its relation with experience of domestic violence during childhood have been explored. Participants' educational levels, current age and age of marriage, style of marriage, educational level and age of spouse were not found to be associated with experiencing of domestic violence. Both verbal and physical domestic violence were significantly associated with the economic status of women (p<0.05). The mean SCL-90-R score was 1.40 +/- 0.68 with the highest mean subgroup score under depressive symptoms category (1.80 +/- 0.79). Mean SCL-90-R score showed significant association with the experience of domestic violence (p <= 0.001). Conclusion: Most of the women participated in the study have experienced domestic violence. Both verbal and physical violence increased with lower economic status. Psychiatric symptoms increased with the experience of domestic violence. Considering its high prevalence and detrimental psychological effects, domestic violence should be inquired by clinicians as part of the psychiatric interview.Publication Metadata only Descriptive norms influence alcohol use among high-school students: a social norms study from Istanbul(Taylor and Francis Ltd., 2021) AKVARDAR, YILDIZ; Sönmez Güngör E., Tunca D., Çelebi C., Gündüz A., Karaer G., Kandemir G., Akvardar Y.Background: The social norms approach, which explores the influence of peer norms on health-compromising behaviors in youth, has been found to be effective in the prevention of drug and alcohol use. Our purpose was to identify the influence of peer norms on the tobacco, alcohol and drug use of high-school students. Methods: A sample of high school students in Istanbul were surveyed for their use of tobacco, alcohol and cannabis use. Sociodemographic variables, academic performance, daily life activities, descriptive and injunctive norms among students were assessed and relevant factors were evaluated using descriptive statistics and logistic regression models. Results: 213 students (105 males, 108 females, mean age 16.04 ± 0.96) filled in the questionnaire completely. The lifetime prevalence of tobacco and alcohol use were 29.9% and 30.9%, respectively. Higher perceived rates of peer alcohol use (descriptive norms) predicted higher lifetime alcohol use (OR: 1.17, 95% CI [1.11– 1.38], p = .04). Recent and lifetime use of tobacco significantly predicted recent and lifetime alcohol use (OR: 5.68, 95%CI [2.56–14.28], p < .01; OR: 9.60; 95%CI [3.09–29.89], p < .01). Conclusions: We found that students’ misperceptions about higher peer alcohol use facilitated their own alcohol use. Correcting such misperceptions can contribute to preventive measures in youth. © 2021 Taylor & Francis Group, LLC.Publication Metadata only Psikiyatri polikliniğine başvuran kadın hastalarda aile içi şiddet yaşantısının değerlendirilmesi(2012-11-13) YORGUNER, NEŞE; AKVARDAR, YILDIZ; KURT E., YORGUNER N., SÖNMEZ GÜNGÖR H. E., BULUT N. S., AKVARDAR Y.Publication Metadata only Is early marriage practice a problem for women living in Istanbul? A qualitative study(SPRINGER WIEN, 2021) BAYSAK, ERENSU; Baysak, Erensu; Yorguner, Nese; Kandemir, Guler; Denizman, Isik Akyollu; Akvardar, YildizEarly marriages (EM) adversely affect women's physical and mental health, education, and social status. The current study aimed to analyze effects of EM through the thoughts, experiences, and suggestions of women who were married under the age of eighteen in Istanbul, Turkey, and the key informants (e.g., social worker, psychologist, obstetrician) who have encountered EM. In-depth interviews were conducted with fifteen women who were married before age 18, recruited from psychiatry outpatient department and eleven key informants. Thematic analysis was used. Low educated, poor family environment with domestic violence and neglect of children, loss of parents, lack of access to education, and traditional social structure were stated as causes for EM. Families' attitudes about EM were characterized as their daughter's reputation would be tarnished which implied the daughter's premarital relationships would be perceived as immoral by community. All women experienced traditional, aggressive rituals for the first night of marriage, husbands were mostly insensitive, and coercive resulting a traumatic experience. Women were subjected to physical, sexual, psychological, and emotional violence; most of them were socially isolated after marriage with restrictions imposed by their spouses and spouses' family that limited communication with their loved ones. The women generally felt unprepared for adult sexual life and motherhood. In order to prevent EM, raising parents' awareness about EM, supporting girls' education, and enforcing legitimate regulations were recommended. Early marriages violate human rights, cause negative consequences for health both physically and mentally, and deepen social inequality for women. All the participants suggested a better functioning legislative arrangement. The male dominated society that legitimizes child marriages and other harmful traditional practices should be addressed.Publication Open Access Personal and perceived peer use and attitudes towards the use of nonmedical prescription stimulants to improve academic performance among university students in seven European countries(ELSEVIER IRELAND LTD, 2016-11) AKVARDAR, YILDIZ; Helmer, S. M.; Pischke, C. R.; Van Hal, G.; Vriesacker, B.; Dempsey, R. C.; Akvardar, Y.; Guillen-Grima, F.; Salonna, F.; Stock, C.; Zeeb, H.Background: Overestimations of non-prescribed stimulant use of peers are well documented in the USA and have also been identified as predictive of personal stimulant consumption. This study aimed to examine whether overestimations of peer use and approval of the use are associated with personal use and attitude towards the use of non-prescribed stimulants among European university students. Method: The EU funded 'Social Norms Intervention for the prevention of Polydrug usE (SNIPE)' study was conducted in seven European countries. In a web-based questionnaire, 4482 students were asked about their personal use and their attitude towards non-prescribed stimulant use, as well as the perceived peer use and peer attitude. Results: 59% of students thought that the majority of their peers used non-prescribed stimulants more frequently than themselves, and only 4% thought that the use of the majority was lower than their personal use. The perception that the majority of peers had used non-prescribed stimulants at least once was significantly associated with higher odds for personal use of non-prescribed stimulants (OR: 3.30, 95% CI: 2.32-4.71). In addition, the perception that the majority of peers approved of the non-prescribed use of stimulants was associated with a 4.03 (95% CI: 3.35-4.84) times higher likelihood for personal approval. Discussion: European university students generally perceived the non-prescribed use of stimulants of peers to be higher than their personal use. This perception, as well as a perception of higher approval in the peer group, was associated with a higher likelihood of personal non-prescribed stimulant medication use and approval. (C) 2016 Published by Elsevier Ireland Ltd.Publication Open Access Social norms regarding alcohol use and associated factors among university students in Turkey(UNIV SAO PAULO, INST PSIQUIATRIA, 2019-04) YÜCE, HÜSEYİN; Gunduz, Anil; Sakarya, Bel; Sonmez, Ekin; Celebi, Cengiz; Yuce, Hoseyin; Akvardar, YildizBackground: Misperceptions on the higher rates of peer alcohol use are predictive of increased personal use among university students. Objectives: This study aims to assess the prevalence, perceived peers' social norms and other predictors of alcohol use in a sample of Turkish university students. Methods: This study is established upon the baseline Turkish data on alcohol use of the project Social Norms Intervention for the prevention of Polydrug usE (SNIPE). The data was obtained by a self-reported, online questionnaire from 858 students of Marmara University who were registered to the study web page. Results: Alcohol use and drunkenness rates were 62.6%, and 40.9%, respectively. Twenty point two percent of students reported drinking alcohol at least once a week in the last two months. Majority of students (70.4%) reported that religion has an important or very important role in their lives. Perceived higher frequency of peer alcohol use (p<0.000) and drunkenness (p<0.000) were significantly associated with personal alcohol use frequency. Tobacco use rate was 60.2% and positively associated with alcohol use frequency (p<0.000). In all participants, male gender (OR: 1.56; 95% CI: 1.07-2.28), giving less importance to religion (OR: 20.91; 95% CI: 10.95-39.95), tobacco use everyday/almost everyday (OR: 17.88; 95% CI: 9.33-34.29), perceived positive peer attitude towards alcohol use (OR: 2.192; 95% CI: 1.25-3.82) and perceived higher frequency of peer alcohol use (OR: 3.487; 95% CI: 1.66-7.31) were found to be associated risk factors for alcohol use. Age (OR: 1.186, CI 95%: 1.03-1.36) and perceived positive peer attitude towards alcohol use (OR 3.86, CI 95%: 1.84-8.09) were the additional risk factors among female student whereas perceived positive peer alcohol use frequency (OR: 8.08, CI 95%: 2.40-27.10) among male students. Discussion: As the first study conducted in Turkey applying social norms theory, our results indicate the noticeable misperceptions of students regarding their peers' alcohol use. Based on our results, targeting both tobacco and alcohol use, and a gender-sensitive approach employing social norms interventions may enhance the preventive strategies for risky alcohol use among university students.Publication Open Access Depressive symptoms in higher education students during the COVID-19 pandemic: the role of containment measures(2022-06-01) AKVARDAR, YILDIZ; Buffel V., Van de Velde S., AKVARDAR Y., Bask M., Brault M., Busse H., Chatzittofis A., Ladner J., Rabiee-khan F., Stathopoulou T., et al.Background Students are a vulnerable group for the indirect impact of the COVID-19 pandemic, particularly their mental health. This paper examined the cross-national variation in students\" depressive symtoms and whether this can be related to the various protective measures implemented in response to the initial stage of the COVID-19 outbreak. Methods Student data stem from the COVID-19 International Student Well-being Study, covering 26 countries during the first wave of the COVID-19 pandemic. Country-level data on government responses to the COVID-19 pandemic were retrieved from the Oxford COVID-19 Tracker. Multilevel analyses were performed to estimate the impact of the containment and economic support measures on students\" depressive symptoms (n = 78 312). Results School and workplace closures, and stay-at-home restrictions were positively related to students\" depressive symptoms during the COVID-19 pandemic, while none of the economic support measures significantly related to depressive symptoms. Countries\" scores on the index of these containment measures explained 1.5% of the cross-national variation in students\" depressive symptoms (5.3%). This containment index\"s effect was stable, even when controlling for the economic support index, students\" characteristics, and countries\" epidemiological context and economic conditions. Conclusions Our findings raise concerns about the potential adverse effects of existing containment measures (especially the closure of schools and workplaces and stay-at-home restrictions) on students\" mental health.
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