Person: KARĞIN, DİCLE
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KARĞIN
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DİCLE
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Publication Metadata only Probiotic Foods From Past To Present In Anatolian Culture(2016-09-07) İÇEN, HAYRUNİSA; KARĞIN, DİCLE; AKDUMAN, GÜL; İçen H., Karğın D., Akduman G., Güneş F. E.Publication Open Access Evaluation Of healthy nutrition index-2015, dental health and oral flora relationship in school-age children(2021-10-01) KARĞIN, DİCLE; OMURTAG KORKMAZ, BURCU İREM; KARĞIN D., OMURTAG KORKMAZ B. İ., MUNGAN C., AKYÜZ S. H.Objective: The aim of the study is to evaluate the role of diet quality and oral flora on the dental health in the childhood period. Methods: A cross-sectional study was carried out with the participation of 98 children aged 9-14 and their parents who applied to the Pedodontics Clinic Dental Faculty of Marmara University. The decayed, missing, filled tooth and surfaces and DMFT, DMFS indexes were determined through visual dental examination. Anthropometric measurements and saliva samples, as well as 24 h food consumption records, were taken from each child. Saliva samples were analysed microbiologically. To evaluate dietary quality from intakes Healthy Eating Index-2015 (HEI-2015) scores were calculated. Results: The mean age of children was 10.8±1.5 and study sample compromised 44.9% males and 55.1% females. 75% of the children had normal height and 58.2% of them had normal BMI according to World Health Organisation (WHO) references. The mean number of decayed tooth and surface was 3.07±2.35; 4.34±3.78 respectively and the mean number of DMFT and DMFS indexes were 5.88±2.31; 8.05±4.58 respectively. The mean number of decayed, missing, filled teeth and DMFT, DMFS scores were found to be higher in children with poor diets (according to HEI-2015) but the difference was not statistically significant (p>0.05). The presence of lactobacilli in saliva samples of 5.5% of the children was observed and children have lactobacilli in their saliva samples had more decayed teeth (p<0.05). Conclusion: The study findings illustrate the relationship between decay development and lactobacilli. Further studies with high sample sizes are needed to examine the diet quality and oral health.Publication Open Access Effects of Cornus mas L. on lipid peroxidation and anti-oxidative enzyme activity in high fat diet fed rats(2023-02-01) KARĞIN, DİCLE; YAVUZ, AYŞE NUR; ÇAM, MUHAMMET EMİN; AKTAÇ, ŞULE; Karğın D., Aktaç Ş., Yavuz A. N., Çam M. E.Cornelian cherry (Cornus mas L.) has been used for centuries as a traditional herbal medicine in Europe and Asia. In this study, we aimed to describe the effect of Cornus mas L. (C. mas) on the activity of the antioxidant enzymes and a detoxification agent in rats fed a high-fat diet. Forty-eight adult Sprague Dawley rats were randomly assigned to six groups of eight animals each: Standard diet (Control), High Fat Diet (HFD), HFD + C. mas (200 mg/kg/day; 8 weeks), HFD + Atorvastatin (20 mg/kg/day; 8 weeks), HFD post-treated with C. mas (200 mg/kg/day; 4 weeks), HFD posttreated with Atorvastatin (20 mg/kg/day; 4 weeks). The activity of the antioxidant enzymes, Superoxide dismutase (SOD), Catalase (CAT), Glutathione peroxidase (GPx), detoxification agent glutathione (GSH), and oxidative stress parameter thiobarbituric acid reactive substances (TBARS) were measured in the liver tissues. GPx, SOD, and CAT enzyme levels were decreased in HFD groups compared to the control (p < 0.05). However, Cornus mas L. promoted antioxidant activity by increasing GPx, SOD, and CAT enzymes and It also reduced oxidative stress (as an increase in GSH) both in the HFD + C. mas group and the HFD post-treated C. mas group compared to the HFD group (p < 0.05). Our study showed that feeding a high-fat diet increases oxidative stress. Cornus mas L treatment improves antioxidant enzyme activity and oxidative stress parameters in the liver tissues of rats.