Publication:
Phytochemical screening and biological evaluation of Salvia hydrangea Dc. ex Benth. growing in eastern Anatolia

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dc.contributor.authorTAŞKIN, TURGUT
dc.contributor.authorsToplan G. G., KÜRKÇÜOĞLU M., GÖGER F., TAŞKIN T., Civas A., İŞCAN G., Ecevit-Genc G., Mat A., Baser K. H. C.
dc.date.accessioned2023-07-25T10:48:44Z
dc.date.available2023-07-25T10:48:44Z
dc.date.issued2022-07-01
dc.description.abstractSalvia species have lately gained significant interest as a result of their suitable utilization in various industries. In the current study, S. hydrangea, one of the most consumed sages in the eastern region of Turkey, has been evaluated for phytochemical composition as well as in vitro pharmacological potential comparatively for the first time. The phytochemical composition of S.hydrangea was investigated by LC-MS/MS, GC-FID, and GC/MS. To reveal its biological activities, antioxidant, antimicrobial, and also acetylcholinesterase activities of different solvent extracts such as water, n-hexane, chloroform, and methanol were determined. According to GC-GC/MS analysis, the primary components of the oil were identified as camphor (46.0%), 1,8-cineole (7.5%), camphene (6.8%), limonene (6.5%), beta-pinene (6.11%) and alpha-pinene (5.6%). Additionally, in the infusion and methanol extract, rosmarinic acid and luteolin glycoside were detected as predominant phenolics by LCMS/MS. In DPPH center dot, CUPRAC, and FRAP test results of the samples indicated strong to moderate antioxidant ability in all samples studied, additionally, among them, the infusion exhibited significant acetylcholine inhibition properties comparable with galanthamine. With regard to antimicrobial activity, all of the tested microorganisms had MIC values ranging from 15 to 2000 mu g/mL. Based on these findings, S. hydrangea may have promising properties for a variety of industrial applications in the pharmaceutical, food, and cosmetic industries. (C) 2022 SAAB. Published by Elsevier B.V. All rights reserved.
dc.identifier.citationToplan G. G., KÜRKÇÜOĞLU M., GÖGER F., TAŞKIN T., Civas A., İŞCAN G., Ecevit-Genc G., Mat A., Baser K. H. C., "Phytochemical screening and biological evaluation of Salvia hydrangea Dc. ex Benth. growing in eastern Anatolia", SOUTH AFRICAN JOURNAL OF BOTANY, cilt.147, ss.799-807, 2022
dc.identifier.doi10.1016/j.sajb.2022.03.021
dc.identifier.endpage807
dc.identifier.issn0254-6299
dc.identifier.startpage799
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dc.identifier.urihttps://hdl.handle.net/11424/291599
dc.identifier.volume147
dc.language.isoeng
dc.relation.ispartofSOUTH AFRICAN JOURNAL OF BOTANY
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTarımsal Bilimler
dc.subjectZiraat
dc.subjectBitki Koruma
dc.subjectFitopatoloji
dc.subjectAgricultural Sciences
dc.subjectAgriculture
dc.subjectPlant Protection
dc.subjectPhytopathology
dc.subjectBİTKİ BİLİMLERİ
dc.subjectBitki ve Hayvan Bilimleri
dc.subjectTarım ve Çevre Bilimleri (AGE)
dc.subjectPLANT SCIENCES
dc.subjectPLANT & ANIMAL SCIENCE
dc.subjectAgriculture & Environment Sciences (AGE)
dc.subjectKüçük hayvanlar
dc.subjectBitki Bilimi
dc.subjectSağlık Bilimleri
dc.subjectYaşam Bilimleri
dc.subjectSmall Animals
dc.subjectPlant Science
dc.subjectHealth Sciences
dc.subjectLife Sciences
dc.subjectSalvia hydrangea
dc.subjectVolatile oil
dc.subjectAntimicrobial
dc.subjectGC-GC/MS
dc.subjectAntioxidant activity
dc.subjectLC-MS/MS
dc.subjectVITRO ANTIOXIDANT PROPERTIES
dc.subjectESSENTIAL OILS
dc.subjectPHENOLIC COMPOSITION
dc.subjectOFFICINALIS L.
dc.subjectROSMARINUS-OFFICINALIS
dc.subjectACETYLCHOLINESTERASE
dc.subjectCONSTITUENTS
dc.subjectSPP.
dc.subjectFOOD
dc.subjectSAGE
dc.titlePhytochemical screening and biological evaluation of Salvia hydrangea Dc. ex Benth. growing in eastern Anatolia
dc.typearticle
dspace.entity.typePublication
local.avesis.iddcccf8bf-d34f-4c65-808a-177b47a2060a
local.indexed.atWOS
local.indexed.atSCOPUS
relation.isAuthorOfPublication265414e9-485c-42b8-903a-c467f6b49b84
relation.isAuthorOfPublication.latestForDiscovery265414e9-485c-42b8-903a-c467f6b49b84

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