Publication:
An analysis of 1344 consecutive acute intoxication cases admitted to an academic emergency medicine department in Turkey

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dc.contributor.authorDENİZBAŞI ALTINOK, ARZU
dc.contributor.authorsSacak, Melis Efeoglu; Akoglu, Haldun; Onur, Ozge; Altinok, Arzu Denizbasi
dc.date.accessioned2022-03-14T09:51:42Z
dc.date.available2022-03-14T09:51:42Z
dc.date.issued2020
dc.description.abstractOBJECTIVE: One of the major causes of emergency department (ED) visits is acute poisoning. Acute intoxications occur soon after either single or multiple exposures to toxic substances, and they started to be a more serious problem in developing countries. The objective of this study was to investigate the local patterns of acute intoxications, as well as clinical and sociodemographic characteristics of patients with acute poisoning, admitted to our hospital's ED. METHODS: This single-center, retrospective study was conducted using medical records of consecutive patients admitted to the ED between January 2016 and December 2017. RESULTS: A total of 1344 patients were included in the statistical analysis. Of these, 673 (50.1%) were female. Mean (+/- SD) age was 32.2 (+/- 12.0), ranging between 17 and 84 years. The highest number of poisoning cases was observed in summer, especially in July (10.0%) and August (11.8%), whereas lowest number of admissions related to poisoning occurred during winter in November (5.1%) and December (5.2%). Among admitted cases, many were suicide attempts (55.7%) followed by non-intentional (accidental) ingestion of non-pharmaceutical (n=553, 41.2%) and pharmaceutical agents (n=42, 3.1%). Single agents were the most common cause of acute intoxications (63.2%) rather than multidrug intoxications. Most frequently observed causes of poisonings were recreational substances (30.0%) and agents exposed by inhalation (13.2%). INR, lactate, and pH levels at admission were significant predictors of 7-day mortality without a significant paired difference between each other. The AUCs for each were 0.89 (SE 0.04; p<0.0001), 0.84 (SE 0.10; p=0.0007), and 0.79 (SE 0.11; p=0.0102), respectively. CONCLUSION: We conclude that recreational substances and medicinal drug intoxications were the leading cause of acute poisonings in our region, occurring mostly during the summer.
dc.identifier.doi10.14744/nci.2020.98957
dc.identifier.issn2148-4902
dc.identifier.pubmed34585073
dc.identifier.urihttps://hdl.handle.net/11424/243365
dc.identifier.wosWOS:000693118100010
dc.language.isoeng
dc.publisherKARE PUBL
dc.relation.ispartofNORTHERN CLINICS OF ISTANBUL
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectDemographics
dc.subjectpoisoning
dc.subjecttoxicity
dc.subjectDEPARTMENT PATIENTS
dc.subjectPROGNOSTIC-FACTORS
dc.subjectARTERIAL LACTATE
dc.subjectDRUG-OVERDOSE
dc.subjectPOISONINGS
dc.subjectPROFILE
dc.subjectLEVEL
dc.titleAn analysis of 1344 consecutive acute intoxication cases admitted to an academic emergency medicine department in Turkey
dc.typearticle
dspace.entity.typePublication
local.avesis.idfa98fb8a-57b2-4020-8395-215375967cf2
local.import.packageSS16
local.indexed.atWOS
local.indexed.atPUBMED
local.indexed.atTRDIZIN
local.journal.numberofpages8
oaire.citation.endPage384
oaire.citation.issue4
oaire.citation.startPage377
oaire.citation.titleNORTHERN CLINICS OF ISTANBUL
oaire.citation.volume8
relation.isAuthorOfPublication85d7879a-b827-49ad-8b5f-77e6661077c7
relation.isAuthorOfPublication.latestForDiscovery85d7879a-b827-49ad-8b5f-77e6661077c7

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