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The structural, functional and electrophysiological assessment of paraspinal musculature of patients with ankylosing spondylitis and non-radiographic axial spondyloarthropathy

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dc.contributor.authorÖZTÜRK, EKİM CAN
dc.contributor.authorsOzturk, Ekim Can; Yagci, Ilker
dc.date.accessioned2022-03-12T22:55:06Z
dc.date.available2022-03-12T22:55:06Z
dc.date.issued2021
dc.description.abstractParavertebral muscles are affected in spondyloarthritis. Decreased mobility of spine may lead to atrophy and fatty degeneration of these muscles. The objective of this study was to compare the sonographic, electrophysiological and magnetic resonance imaging (MRI) features of paraspinal muscles between patients with ankylosing spondylitis (AS) and non-radiographic axial spondyloarthritis (nr-axSpA). The patients who were diagnosed as AS with modified New York criteria and those as nr-axSpA with ASAS 2009 criteria were enrolled. Clinical evaluation, electrophysiological examination including nerve conduction studies and needle electromyography (EMG) for lower extremities and paraspinal mapping (PSM) were performed by the first examiner. The second examiner measured lumbar multifidus areas, graded the fatty degeneration of the muscle at different levels in T2 weighted axial MRI and also performed the ultrasonographic evaluation. A total of 19 patients with AS and 14 patients with nr-axSpA were evaluated. MRI of 2 patients with AS could not be obtained. Right lumbar multifidus area/vertebra area (MV ratio) was smaller in AS patients at L3 level (p 0,029); there were no significant differences in other levels. Fatty degeneration was also higher in AS patients in left multifidus at L5-S1 disc level (p 0,015). PSM scores that demonstrate the extent of denervation in paraspinal muscles were significantly higher in AS patients than in nr-axSpA patients (p < 0,001). Patients with AS have more fatty degeneration and denervation in paraspinal muscles. These processes may also contribute the severity of pain and disability. The relationship between paraspinal muscle denervation and progression of fatty degeneration should further be revealed.
dc.identifier.doi10.1007/s00296-020-04781-4
dc.identifier.eissn1437-160X
dc.identifier.issn0172-8172
dc.identifier.pubmed33502552
dc.identifier.urihttps://hdl.handle.net/11424/236647
dc.identifier.wosWOS:000612283200003
dc.language.isoeng
dc.publisherSPRINGER HEIDELBERG
dc.relation.ispartofRHEUMATOLOGY INTERNATIONAL
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectParaspinal mapping
dc.subjectMultifidus
dc.subjectElectromyography
dc.subjectAnkylosing spondylitis
dc.subjectNon-radiographic axial spondyloarthritis
dc.subjectUltrasonography
dc.titleThe structural, functional and electrophysiological assessment of paraspinal musculature of patients with ankylosing spondylitis and non-radiographic axial spondyloarthropathy
dc.typearticle
dspace.entity.typePublication
local.avesis.id0f61c730-d0aa-4853-bf04-26a6fb81ca54
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages9
oaire.citation.endPage603
oaire.citation.issue3
oaire.citation.startPage595
oaire.citation.titleRHEUMATOLOGY INTERNATIONAL
oaire.citation.volume41
relation.isAuthorOfPublication72acf624-37c5-40fc-bc9a-6c3b52effade
relation.isAuthorOfPublication.latestForDiscovery72acf624-37c5-40fc-bc9a-6c3b52effade

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