Publication:
Increasing carbapenem resistance due to the clonal dissemination of oxacillinase (OXA-23 and OXA-58)-producing Acinetobacter baumannii: report from the Turkish SENTRY Program sites

Simple item page
dc.contributor.authorKORTEN, VOLKAN
dc.contributor.authorsGur, Deniz; Korten, Volken; Unal, Serhat; Deshpande, Lalitagauri M.; Castanheira, Mariana
dc.date.accessioned2022-03-14T08:14:18Z
dc.date.available2022-03-14T08:14:18Z
dc.date.issued2008-12-01
dc.description.abstractA significant increase in carbapenem-resistance rates among Acinetobacter baumannii isolates collected in two Turkish medical centres was detected in the 2000-2006 period (20-60%) by the SENTRY Antimicrobial Surveillance Program. Carbapenem-resistant strains from 2006 were evaluated for the presence of encoding genes and epidemic clonality. OXA-58-like and OXA-23-like carbapenemase-producing strains were detected in both medical institutions. Seventeen out of 18 strains from Ankara were positive for bla(OXA-58) primers and belonged to the same clone, whilst 26 isolates (25 from Istanbul and one from Ankara) harboured bla(OXA-23)-like genes and showed identical or similar PFGE patterns. Isolates producing OXA-23-like carbapenemases were more resistant than OXA-58-like carbapenemase producers to non-carbapenem antimicrobial agents. Carbapenem resistance in these institutions was observed to be largely driven by the dissemination of clones producing OXA-type carbapenemases.
dc.identifier.doi10.1099/jmm.0.2008/002469-0
dc.identifier.eissn1473-5644
dc.identifier.issn0022-2615
dc.identifier.pubmed19018025
dc.identifier.urihttps://hdl.handle.net/11424/241226
dc.identifier.wosWOS:000261660600013
dc.language.isoeng
dc.publisherMICROBIOLOGY SOC
dc.relation.ispartofJOURNAL OF MEDICAL MICROBIOLOGY
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBETA-LACTAMASES
dc.subjectBLA(OXA-23)
dc.subjectOXA-58
dc.titleIncreasing carbapenem resistance due to the clonal dissemination of oxacillinase (OXA-23 and OXA-58)-producing Acinetobacter baumannii: report from the Turkish SENTRY Program sites
dc.typearticle
dspace.entity.typePublication
local.avesis.id176ef4a9-0a17-4e4d-a251-097575452924
local.import.packageSS16
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages4
oaire.citation.endPage1532
oaire.citation.issue12
oaire.citation.startPage1529
oaire.citation.titleJOURNAL OF MEDICAL MICROBIOLOGY
oaire.citation.volume57
relation.isAuthorOfPublication27f6afa3-0e46-45c9-a302-a6493c69bffb
relation.isAuthorOfPublication.latestForDiscovery27f6afa3-0e46-45c9-a302-a6493c69bffb

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Gur et al. - 2008 - Increasing carbapenem resistance due to the clonal.pdf
Size:
104.07 KB
Format:
Adobe Portable Document Format
Download

Collections

Research Outputs