Publication:
The Assessment of Presenteeism and Activity Impairment in Behcet's Syndrome and Recurrent Aphthous Stomatitis: A multicentre Study

Simple item page
dc.contributor.authorALİBAZ ÖNER, FATMA
dc.contributor.authorsKaracayli, Umit; Adesanya, Adebowale; Aksoy, Aysun; Belem, Joice M. F. M.; Cardin, Natália Borges; Sarı, Fatma Busra; Beyhan, Tuğba Emine; Çelik, Zülal; Karacayli, Ceren; Alibaz-Öner, Fatma; Inanç, Nevsun; Ergun, Tülin; Yay, Meral; Madanat, Wafa; Silva de Souza, Alexandre Wagner; Fortune, Farida; Direskeneli, Haner; Mumcu, Gonca
dc.date.accessioned2022-03-15T12:01:29Z
dc.date.available2022-03-15T12:01:29Z
dc.date.issued2021
dc.description.abstractOBJECTIVE: To evaluate key factors for Presenteeism and Activity impairment in multinational patients with Behçet's syndrome (BS) and recurrent aphthous stomatitis (RAS). METHODS: In this cross-sectional study, 364 BS patients from Jordan, Brazil, the United Kingdom and Turkey and 143 RAS patients from the United Kingdom and Turkey were included. Work Productivity Activity Impairment (WPAI) scale was used for Presenteeism and Activity impairment. Mediation analyses were performed to evaluate both direct and indirect causal effects. RESULTS: Presenteeism score was higher in active patients with genital ulcers and eye involvement as well as patients with comorbidities and current smokers than the others in BS (p< 0.05). In RAS, Presenteeism score was elevated by oral ulcer activity in the direct path (p= 0.0073) and long disease duration as a mediator in the indirect path (p= 0.0191).Patients with active joint involvement had poor scores in Absenteeism, Presenteeism, Overall impairment and Activity impairment compared with those of inactive patients (p < 0.05). Using mediation analysis, the Activity impairment score was directly mediated by joint activity (p = 0.0001) and indirectly mediated through oral ulcer-related pain in BS (p = 0.0309). CONCLUSION: In BS, Presenteeism was associated with disease activity, presence of comorbidities and being a current smoker, whereas in RAS, Presenteeism was associated with oral ulcer activity and increased length of the disease. Moreover, Activity impairment was adversely affected by joint activity and oral ulcer related pain in BS. Patients need to be empowered by using appropriate treatment strategies in their working environment and daily life.
dc.identifier.doi10.1093/rheumatology/keab581
dc.identifier.issn1462-0332
dc.identifier.pubmedPMID: 34289015
dc.identifier.urihttps://hdl.handle.net/11424/252953
dc.language.isoeng
dc.relation.ispartofRheumatology (Oxford, England)
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectBehçet’s syndrome
dc.subjectMediation analysis
dc.subjectAphthous stomatitis
dc.subjectDaily activity
dc.subjectPresenteeism
dc.titleThe Assessment of Presenteeism and Activity Impairment in Behcet's Syndrome and Recurrent Aphthous Stomatitis: A multicentre Study
dc.typearticle
dspace.entity.typePublication
local.avesis.idf24d4800-957e-4cd7-90b2-ca1d77b6e8b4
local.import.packageSS23
local.import.sourcePubMed
local.indexed.atPUBMED
oaire.citation.startPagekeab581
oaire.citation.titleRheumatology (Oxford, England)
relation.isAuthorOfPublicatione995a136-8c56-4192-bebe-fe522b567ef1
relation.isAuthorOfPublication.latestForDiscoverye995a136-8c56-4192-bebe-fe522b567ef1

Files

Collections

Research Outputs