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Oral ulcer activity in Behcet's disease: Poor medication adherence is an underestimated risk factor

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dc.contributor.authorALİBAZ ÖNER, FATMA
dc.contributor.authorsMumcu, Gonca; Alibaz-Oner, Fatma; Oner, Sibel Yilmaz; Ozen, Gulsen; Atagunduz, Pamir; Inanc, Nevsun; Koksal, Leyla; Ergun, Tulin; Direskeneli, Haner
dc.date.accessioned2022-03-14T08:17:51Z
dc.date.available2022-03-14T08:17:51Z
dc.date.issued2017-06-12
dc.description.abstractObjective: The aim of this study was to evaluate the relationship between oral ulcer activity and medication adherence according to gender in Behcet's disease (BD) patients. Material and Methods: The study group included 330 BD patients (F/M: 167/163, mean age: 38.5 +/- 10.5 years). Oral ulcer activity and medication adherence were evaluated in the previous month. Medication adherence was evaluated using the 8-item Morisky Medication Adherence Scale (MMAS-8) having a score range of 0 to 8 with high scores indicating better adherence. Low adherence was defined as < 6 points on MMAS-8. Results: Over half of the group had active oral ulcers (n= 219, 66.4%) within the month preceding the visit. The number of oral ulcers was significantly higher in female patients with low medication adherence (2.39 +/- 3.24) than in the rest of the female group (1.28 +/- 2.05; p= 0.023). Although a similar trend was also observed in male patients (2.14 +/- 3.3 vs. 1.81 +/- 2.31), a significant relationship was not observed (p= 0.89). The frequency of medication intake per day was lower in patients with high medication adherence than in the rest of the study group (p= 0.04). Conclusion: Low medication adherence is a hidden risk factor in the management of BD. Poor adherence was associated with oral ulcer activity in female BD patients.
dc.identifier.doi10.5152/eurjrheum.2017.160094
dc.identifier.eissn2148-4279
dc.identifier.issn2147-9720
dc.identifier.pubmed28638682
dc.identifier.urihttps://hdl.handle.net/11424/241467
dc.identifier.wosWOS:000403583200006
dc.language.isoeng
dc.publisherAVES
dc.relation.ispartofEUROPEAN JOURNAL OF RHEUMATOLOGY
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectMedication adherence
dc.subjectoral ulcer
dc.subjectBehcet's disease
dc.subjectCROSS-CULTURAL ADAPTATION
dc.subjectRHEUMATOID-ARTHRITIS
dc.subjectPREDICTIVE-VALIDITY
dc.subjectNONADHERENCE
dc.subjectMANAGEMENT
dc.subjectQUESTIONNAIRE
dc.subjectCOLCHICINE
dc.titleOral ulcer activity in Behcet's disease: Poor medication adherence is an underestimated risk factor
dc.typearticle
dspace.entity.typePublication
local.avesis.idc6c66333-56de-4eaf-892e-d2e77347d69b
local.import.packageSS16
local.indexed.atWOS
local.indexed.atPUBMED
local.indexed.atTRDIZIN
local.journal.numberofpages4
oaire.citation.endPage112
oaire.citation.issue2
oaire.citation.startPage109
oaire.citation.titleEUROPEAN JOURNAL OF RHEUMATOLOGY
oaire.citation.volume4
relation.isAuthorOfPublicatione995a136-8c56-4192-bebe-fe522b567ef1
relation.isAuthorOfPublication.latestForDiscoverye995a136-8c56-4192-bebe-fe522b567ef1

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