Publication: Phytochemical studies of Helichrysum armenium subsp. armenium and its antioxidant, acetylcholinesterase, and antimicrobial activities
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2024-01-01
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Abstract
Helichrysum armenium subsp. armenium plant was extracted with the Soxhlet apparatus. The obtained extract was fractionated and, respectively, AHB (petroleum ether–60% ethanol-chloroform), AHC (ethanol-toluene), AHD (ethanol-chloroform), and AHE (ethanol-ethylacetate) extracts were obtained. Then, antimicrobial, antioxidant, and acetylcholinesterase activity studies were performed on these extracts. In this study, with the using the LC-HRMS method from the aerial parts of Helichrysum armenium subsp. armenium, the flavonoids: apigenin, apigenin 7-glucoside, apigenin 7-methylate, luteolin 7-glucoside, kaempferol, quercetin, quercitrin, (+)-trans taxifolin, (-)-epicatechin gallate, sinensetin, rutin, 3\"-o-methyl quercetin, hispidulin, chrysin, acacetin, genkwanin, chrysoeriol; the phenolic acids: chlorogenic acid, ascorbic acid, fumaric acid, caffeic acid, salicylic acid, caffeic acid phenethyl ester, emodin, vanilic acid; the alkaloid: caffeine and the saponoside; glycyrrhizic acid were obtained.
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Temel Eczacılık Bilimleri, Eczacılık, Yaşam Bilimleri, Sağlık Bilimleri, Temel Bilimler, Basic Pharmaceutics Sciences, Pharmacology and Therapeutics, Life Sciences, Health Sciences, Natural Sciences, Yaşam Bilimleri (LIFE), Farmakoloji ve Toksikoloji, FARMAKOLOJİ VE ECZACILIK, Life Sciences (LIFE), PHARMACOLOGY & TOXICOLOGY, PHARMACOLOGY & PHARMACY, Genel Farmakoloji, Toksikoloji ve Eczacılık, Farmakoloji (tıbbi), General Pharmacology, Toxicology and Pharmaceutics, Pharmacology (medical), acetylcolinesterase, antimicrobial, antioxidant, Helichrysum armenium subsp. armenium, LC-HRMS, phenolic compounds
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Kekeç N., TAŞKIN T., AĞAR D. N., ÖZBEK ÇELİK B., KÜLTÜR Ş., SÜZGEÇ SELÇUK S., "Phytochemical studies of Helichrysum armenium subsp. armenium and its antioxidant, acetylcholinesterase, and antimicrobial activities", Journal of Research in Pharmacy, cilt.28, sa.3, ss.630-640, 2024