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Microbial Profile and Dental Caries in Cleft Lip and Palate Babies Between 0 and 3 Years Old

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dc.contributor.authorYILMAZ, MÜESSER AHU
dc.contributor.authorsDurhan, Muesser Ahu; Topcuoglu, Nursen; Kulekci, Guven; Ozgentas, Ege; Tanboga, Ilknur
dc.date.accessioned2022-03-12T22:38:13Z
dc.date.available2022-03-12T22:38:13Z
dc.date.issued2019
dc.description.abstractObjective: The aim of this study was to examine the microbiological changes in newborn babies with cleft lip palate from birth up to age 3 and to correlate them with their caries levels and mothers' microbiological data and to compare with normal infants. Basic Research Design: Prospective. Settings: Marmara University, Faculty of Dentistry, Pediatric Dentistry Clinic, and Sili Hamidiye Etfal Education and Research Hospital New Born Clinic. Patients/Participants: Cleft lip palate (n = 21) and healthy (n = 13) newborns and their mothers. Material and Methods: Intraoral samples were taken from babies in each group at least 3 times over the 3 years. Saliva samples of the mothers were collected just after the birth of the babies and examined microbiologically. Dental caries was noted as either present or absent. Results: The most frequent microorganisms were candida, found at birth (n = 9, 42%) in cleft palate with or without cleft lip (CP +/- L) group. The number of babies infected with Lactobacilli were found to be significantly higher in the CP +/- L group than in the control group at birth (P = .029) and after eruption of the first primary tooth (P = .030). Mutans Streptococci were found in 10% of babies with CP +/- L at birth. Initial caries was identified in 20% of the babies with an oral cleft compared with 0% of the controls after eruption of the first primary incisors. Conclusion: The results show that the CP +/- L babies must be considered as a group with an increased caries risk.
dc.identifier.doi10.1177/1055665618776428
dc.identifier.eissn1545-1569
dc.identifier.issn1055-6656
dc.identifier.pubmed29800530
dc.identifier.urihttps://hdl.handle.net/11424/235549
dc.identifier.wosWOS:000458733200008
dc.language.isoeng
dc.publisherALLIANCE COMMUNICATIONS GROUP DIVISION ALLEN PRESS
dc.relation.ispartofCLEFT PALATE-CRANIOFACIAL JOURNAL
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectdental health
dc.subjectmicrobiology
dc.subjectmaternal factors
dc.subjectEARLY-CHILDHOOD CARIES
dc.subjectMUTANS STREPTOCOCCI
dc.subjectORAL-HEALTH
dc.subjectAND/OR PALATE
dc.subjectCHILDREN
dc.subjectPREVALENCE
dc.subjectCOLONIZATION
dc.subjectTRANSMISSION
dc.subjectASSOCIATION
dc.subjectINFANTS
dc.titleMicrobial Profile and Dental Caries in Cleft Lip and Palate Babies Between 0 and 3 Years Old
dc.typearticle
dspace.entity.typePublication
local.avesis.id1553dd97-ab4f-4bac-a786-710b458d1102
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages8
local.journal.quartileQ3
oaire.citation.endPage356
oaire.citation.issue3
oaire.citation.startPage349
oaire.citation.titleCLEFT PALATE-CRANIOFACIAL JOURNAL
oaire.citation.volume56
relation.isAuthorOfPublication214ac8db-adbc-4b13-a6ef-3c1de8a50c17
relation.isAuthorOfPublication.latestForDiscovery214ac8db-adbc-4b13-a6ef-3c1de8a50c17

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