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Risk assessment of obstructive sleep apnea syndrome and other sleep disorders in multiple sclerosis patients

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dc.contributor.authorGÜNAL, DİLEK
dc.contributor.authorsSunter, Gulin; Ozden, Hatice Omercikoglu; Vural, Ezgi; Gunal, Dilek Ince; Agan, Kadriye
dc.date.accessioned2022-03-12T22:56:09Z
dc.date.available2022-03-12T22:56:09Z
dc.date.issued2021
dc.description.abstractBackground: The aim of the present study was to determine the possible risk of OSAS in patients with MS through the STOP-BANG questionnaire, and to confirm the pre-diagnosis of OSAS by recording polysomnographic investigation in individuals with high risk. In addition, the relationship between OSAS risk and fatigue, sleepiness, depression, and disability status will be examined. Methods: Totally 97 patients with multiple sclerosis including 36 males and 61 females with an age average of 39.92 +/- 9.11 years. All participants completed the following questionnaires: STOP-Bang, Fatigue Severity Scale (FSS), Epworth sleepiness scale (ESS), Beck Depression Inventory (BDI); disability status of the participants was assessed by Expanded Disability Status Scale (EDSS). Polysomnographic sleep record was applied to the patients with high risk of OSAS according to STOP-BANG test scores. Results: The STOP_BANG questionnaire revealed that 24.7% of the patients were screened as high risk for OSA. Approximately 11.3% of the patients were detected positive for OSAS based on PSG recording. Comparison of MS patients with high risk of OSA with others suggested a significant difference in terms of the age (p = 0.01). ESS positive scores were significantly correlated with positive STOP BANG outcomes (p < 0.001). ESS positive scores were negatively correlated with positive PSG outcomes. Conclusion: The prevalence of OSAS in MS patients based on questionnaire and PSG was found consistent with literature. Similar to the general population, increasing age was found as a risk factor for OSAS in patients with MS. STOP-BANG test may not be an adequate test to diagnose OSAS, especially in MS patients with high fatigue scores.
dc.identifier.doi10.1016/j.clineuro.2021.106749
dc.identifier.eissn1872-6968
dc.identifier.issn0303-8467
dc.identifier.pubmed34126453
dc.identifier.urihttps://hdl.handle.net/11424/236899
dc.identifier.wosWOS:000715564200003
dc.language.isoeng
dc.publisherELSEVIER
dc.relation.ispartofCLINICAL NEUROLOGY AND NEUROSURGERY
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectObstructive sleep apnea syndrome
dc.subjectMultiple sclerosis
dc.subjectSTOP-BANG questionnaire
dc.subjectPolysomnography
dc.subjectDepression
dc.subjectQUALITY-OF-LIFE
dc.subjectSTOP-BANG
dc.subjectFATIGUE
dc.subjectPREVALENCE
dc.subjectIMPACT
dc.subjectQUESTIONNAIRE
dc.subjectEPIDEMIOLOGY
dc.subjectDIAGNOSIS
dc.titleRisk assessment of obstructive sleep apnea syndrome and other sleep disorders in multiple sclerosis patients
dc.typearticle
dspace.entity.typePublication
local.avesis.ide9124f02-36c2-4dc3-a49b-796f04b99784
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.articlenumber106749
local.journal.numberofpages6
oaire.citation.titleCLINICAL NEUROLOGY AND NEUROSURGERY
oaire.citation.volume207
relation.isAuthorOfPublication35469359-99cb-42f9-9a48-bbe160fee6e2
relation.isAuthorOfPublication.latestForDiscovery35469359-99cb-42f9-9a48-bbe160fee6e2

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