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The impact of right ventricular energy failure on the results of pulmonary endarterectomy and balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension

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dc.contributor.authorMUTLU, BÜLENT
dc.contributor.authorYILDIZELİ, BEDRETTİN
dc.contributor.authorATAŞ, HALİL
dc.contributor.authorsBusery R. S., MUTLU B., Akaslan D., Aslanger E., Yildizeli B., ATAŞ H.
dc.date.accessioned2024-07-03T07:08:35Z
dc.date.available2024-07-03T07:08:35Z
dc.date.issued2024-05-31
dc.description.abstractObjective: We aimed to investigate the effect of right ventricular energy failure (RVEF) on hemodynamic and clinical outcomes in patients diagnosed with chronic thromboembolic pulmonary hypertension (CTEPH) undergoing pulmonary endarterectomy (PEA) surgery or balloon pulmonary angioplasty (BPA). Patients and Methods: A total of 100 CTEPH patients planned for PEA or BPA were included in the study. Based on the presence of RVEF during diagnosis, patients divided into two groups. Hemodynamic data from right heart catheterization (RHC) were compared before and after procedures in 3-6 months follow up period. Results: Patients with RVEF revealed a decrease in mean pulmonary artery pressure (mPAP) from 54.67±12.27 mmHg to 36.12±11.76 mmHg (p:<0.001), mean right atrial pressure (mRAP) from 13.40±4.08 mmHg to 9.76±4.56 mmHg (p:0.003), and pulmonary vascular resistance (PVR) from 11.36±5.15 Wood Units (WU) to 5.46±3.30 WU (p <0.001). In the non-RVEF group, mPAP decreased from 38.82±12.61 mmHg to 30.81±10.57 mmHg (p:<0.001), mRAP from 7.09±3.02mmHg to 7.15±3.07mmHg (p: 0.917), and PVR from 6.33±3.65 WU to 4.09±2.31 WU (p:<0.001). Conclusion:The presence of RVEF at the time of diagnosis in CTEPH patients does not have a negative impact on early perioperative and 3-month postoperative outcomes following PEA or BPA. This high-risk patient group demonstrated significant hemodynamic and clinical benefits from both PEA and BPA.
dc.identifier.citationBusery R. S., MUTLU B., Akaslan D., Aslanger E., Yildizeli B., ATAŞ H., "The impact of right ventricular energy failure on the results of pulmonary endarterectomy and balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension", Marmara Medical Journal, cilt.37, sa.2, ss.129-136, 2024
dc.identifier.doi10.5472/marumj.1484403
dc.identifier.endpage136
dc.identifier.issn1019-1941
dc.identifier.issue2
dc.identifier.startpage129
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85196162244&origin=inward
dc.identifier.urihttps://hdl.handle.net/11424/297149
dc.identifier.volume37
dc.language.isoeng
dc.relation.ispartofMarmara Medical Journal
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectTemel Tıp Bilimleri
dc.subjectMedicine
dc.subjectHealth Sciences
dc.subjectFundamental Medical Sciences
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectTIP, GENEL & DAHİLİ
dc.subjectClinical Medicine (MED)
dc.subjectCLINICAL MEDICINE
dc.subjectMEDICINE, GENERAL & INTERNAL
dc.subjectGenel Tıp
dc.subjectGeneral Medicine
dc.subjectChronic thromboembolic pulmonary hypertension
dc.subjectPulmonary balloon angioplasty
dc.subjectPulmonary endarterectomy
dc.subjectRight ventricular energy failure
dc.titleThe impact of right ventricular energy failure on the results of pulmonary endarterectomy and balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension
dc.typearticle
dspace.entity.typePublication
local.avesis.idea8e52a4-d59b-4981-a403-5bd47d1dd4a7
local.indexed.atSCOPUS
relation.isAuthorOfPublication596454aa-45ad-48cd-849f-c92e38afa03c
relation.isAuthorOfPublicationd6b68c67-eea7-4dc3-8688-e8cfbe3bbcd2
relation.isAuthorOfPublicationbce15984-74f0-4f95-ab80-0cec144603fe
relation.isAuthorOfPublication.latestForDiscovery596454aa-45ad-48cd-849f-c92e38afa03c

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