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Do first trimester maternal serum follistatin like 3 levels predict preeclampsia and/or related adverse pregnancy outcomes?

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dc.contributor.authorESİM BÜYÜKBAYRAK, ESRA
dc.contributor.authorsPurut, Y. E.; Buyukbayrak, E. E.; Ercan, F.; Orcun, A.; Menke, M.; Karsidag, A. Y. Karageyim
dc.date.accessioned2022-03-12T22:38:59Z
dc.date.available2022-03-12T22:38:59Z
dc.date.issued2019
dc.description.abstractPurpose of Investigation: The aim of this study is to evaluate whether first trimester maternal serum follistatin like 3 (FSTL3) levels can be used to predict preeclampsia and related obstetric complications. Materials and Methods: The serum levels of FSTL3, pregnancy associated plasma protein A (PAPP-A), and free beta-hCG were determined in the first trimester from a sample of 180 pregnant women. All patients had first- and second-trimester ultrasound evaluations. The pregnancy outcome was defined as 'adverse' if one of the following outcomes were observed: fetal death, preeclampsia, pregnancy-induced hypertension (PIH), delivery of a small infant for gestational age (SGA) or preterm delivery. Results: FSTL3 levels were not significantly different for preeclampsia and related adverse obstetric outcomes compared to the control group (p < 0.05). Only PAPP-A MoM values were lower in the adverse obstetric outcome group than in the control (p = 0.040). There was no significant association among FSTL3 levels and the presence of any complications, according to our ROC curve analyses (p = 0.846). Conclusions: First trimester FSTL3 levels are not predictive for preeclampsia or adverse pregnancy outcomes.
dc.identifier.doi10.12891/ceog4423.2019
dc.identifier.issn0390-6663
dc.identifier.urihttps://hdl.handle.net/11424/235754
dc.identifier.wosWOS:000474747400004
dc.language.isoeng
dc.publisher7847050 CANADA INC
dc.relation.ispartofCLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAdverse outcome
dc.subjectFirst trimester
dc.subjectFollistatin like 3
dc.subjectPreeclampsia
dc.subjectPregnancy
dc.subjectUTERINE ARTERY DOPPLER
dc.subjectACTIVIN-A
dc.subjectNUCHAL TRANSLUCENCY
dc.subjectINHIBIN-A
dc.subjectBETA
dc.subjectEXPRESSION
dc.subjectPROTEIN
dc.subjectCOMPLICATIONS
dc.subjectGESTATION
dc.subjectPLACENTA
dc.titleDo first trimester maternal serum follistatin like 3 levels predict preeclampsia and/or related adverse pregnancy outcomes?
dc.typearticle
dspace.entity.typePublication
local.avesis.idb2ca0415-17ee-4520-8c61-833b9a59ea2c
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.journal.numberofpages6
local.journal.quartileQ4
oaire.citation.endPage200
oaire.citation.issue2
oaire.citation.startPage195
oaire.citation.titleCLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY
oaire.citation.volume46
relation.isAuthorOfPublication884cd9b0-bcf7-4db3-a59d-bc3c07ef19bc
relation.isAuthorOfPublication.latestForDiscovery884cd9b0-bcf7-4db3-a59d-bc3c07ef19bc

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