Publication:
Evaluation of Airway Resistance in Children with Juvenile Idiopathic Arthritis

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dc.contributor.authorKARAKURT, SAİT
dc.contributor.authorsAbul, Mehtap Haktanir; Abul, Yasin; Erguven, Muferet; Karatoprak, Elif Yuksel; Karakurt, Sait; Celikel, Turgay
dc.date.accessioned2022-03-13T12:46:27Z
dc.date.available2022-03-13T12:46:27Z
dc.date.issued2014
dc.description.abstractBackground: Pneumonitis, pleuritis, and pulmonary interstitial infiltration have been described in patients with juvenile idiopathic arthritis (JIA). However, the pulmonary involvement of JIA is not often clinically apparent. There are few studies based on pulmonary function in children having only a diagnosis of JIA. The aim of the present study is to determine whether children with JIA have airway resistance and flow impairments measured by easily applied interrupter technique. Method: We performed interrupter resistance (Rint) measurements in children with JIA and in healthy control subjects who had no respiratory symptoms or diseases. Results: Fifty-eight children with the diagnosis of JIA (Mean age = 12.5 +/- 2.75 years; range 7-17 years) and 33 healthy subjects (Mean age = 11.8 +/- 2.62 years; range 6-16 years) were included in the study. The mean value of tidal peak flow during expiration measured by the interrupter technique was significantly lower in the JIA study group (0.73 +/- 0.11 L/s) compared to the healthy control group (0.79 +/- 0.08 L/s; p = 0.01). Rint values measured during inspiration (Rint(insp)) and during expiration (Rint(exp)) were higher in the JIA study group (Rint(insp) = 0.28 +/- 0.16 Kpa/L/s; Rint(exp) = 0.30 +/- 0.50 Kpa/L/s) compared to the healthy control group (Rint(insp) = 0.26 +/- 0.11 Kpa/L/s; Rint(exp) = 0.23 +/- 0.08 Kpa/L/s; p > 0.05). There was also a positive correlation between C-reactive protein level and median expiratory interrupter resistance (Rint(exp); r = 0.50, p = 0.005). Conclusion: The interrupter technique is a noninvasive and feasible technique and can be used to assess airway abnormalities in children with JIA who cannot successfully complete spirometry.
dc.identifier.doi10.1089/ped.2014.0341
dc.identifier.eissn2151-3228
dc.identifier.issn2151-321X
dc.identifier.urihttps://hdl.handle.net/11424/237931
dc.identifier.wosWOS:000349302400008
dc.language.isoeng
dc.publisherMARY ANN LIEBERT, INC
dc.relation.ispartofPEDIATRIC ALLERGY IMMUNOLOGY AND PULMONOLOGY
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectINTERRUPTER TECHNIQUE
dc.subjectRHEUMATOID-ARTHRITIS
dc.subjectPULMONARY-FUNCTION
dc.subjectMETHOTREXATE THERAPY
dc.subjectPRESCHOOL-CHILDREN
dc.subjectREFERENCE VALUES
dc.subjectLUNG-FUNCTION
dc.subjectYOUNG-CHILDREN
dc.subjectDISEASE
dc.subjectCLASSIFICATION
dc.titleEvaluation of Airway Resistance in Children with Juvenile Idiopathic Arthritis
dc.typearticle
dspace.entity.typePublication
local.avesis.id886445b5-cbbd-46e4-a391-bf53fd03c38b
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.journal.numberofpages5
oaire.citation.endPage142
oaire.citation.issue3
oaire.citation.startPage138
oaire.citation.titlePEDIATRIC ALLERGY IMMUNOLOGY AND PULMONOLOGY
oaire.citation.volume27
relation.isAuthorOfPublicationbe661872-e895-4271-a0b7-82c5368ec000
relation.isAuthorOfPublication.latestForDiscoverybe661872-e895-4271-a0b7-82c5368ec000

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