Publication:
The effects of therapeutic intermittent hypoxia implementation on complete blood count parameters: an experimental animal model

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dc.contributor.authorŞENGÖR, MUSTAFA
dc.contributor.authorYILDIZ ÖZER, AYSEL
dc.contributor.authorKILIÇ, TALHA
dc.contributor.authorsKılıç T., Şengör M., Üstünova S., Kılıç A., Daşkaya H., Yıldız Özer A.
dc.date.accessioned2022-10-03T06:36:06Z
dc.date.available2022-10-03T06:36:06Z
dc.date.issued2022-09-01
dc.description.abstractObjective: Intermittent hypoxia (IH) implementation is a method performed by intermittently decreasing oxygen concentration in inhaled air at specific rate. This method varies between studies in terms of its application. This study aims to examine the changes in Complete Blood Count (CBC) parameters caused by IH implementation at therapeutic dose ranges with a single model. Methods: Ten Sprague Dawley type adult male rats were divided into two groups. In the study group, FiO2 level of inhaled air, was reduced to 10% in hypoxic cycle. 5 minutes normoxia-hypoxia cycle was used in each 30 minutes experiment period for study group. Control group remained in normoxic air for 30 minutes. 1 cc of blood was taken from mandibular vein from all rats at the end of 6th day. CBC analyzes were performed and differences between two groups were investigated. Results: Significant differences were detected in some CBC parameters between the two groups. It was determined that significant increase in MONO (p<0.001), MONO% (p<0.001), MCH (p=0.03), PLT (p=0.013) and PCT (p=0.007) parameters and significant decrease in MPV (p=0.02) parameters, in favor of study group. Conclusion: IH implementation was caused significant changes in MONO, MONO%, MCH, PCT, PLT and MPV parameters in the CBC analysis of rats. Considering the study results, therapeutic IH implementation may thought to have important effects in terms of lung protection and regeneration. Further research may focus on this point for precising and supporting of this study’ results.
dc.identifier.citationKılıç T., Şengör M., Üstünova S., Kılıç A., Daşkaya H., Yıldız Özer A., "The Effects of Therapeutic Intermittent Hypoxia Implementation on Complete Blood Count Parameters: An Experimental Animal Model", CLINICAL AND EXPERIMENTAL HEALTH SCIENCES, cilt.12, sa.3, ss.746-752, 2022
dc.identifier.doi10.33808/clinexphealthsci.1018541
dc.identifier.endpage752
dc.identifier.issn2459-1459
dc.identifier.issue3
dc.identifier.startpage746
dc.identifier.urihttps://dergipark.org.tr/tr/pub/clinexphealthsci/issue/72731/1018541
dc.identifier.urihttps://hdl.handle.net/11424/282030
dc.identifier.volume12
dc.language.isoeng
dc.relation.ispartofCLINICAL AND EXPERIMENTAL HEALTH SCIENCES
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectSağlık Bilimleri
dc.subjectFizyoterapi ve Rehabilitasyon
dc.subjectHealth Sciences
dc.subjectPhysical therapy and rehabilitation
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectREHABİLİTASYON
dc.subjectClinical Medicine (MED)
dc.subjectCLINICAL MEDICINE
dc.subjectREHABILITATION
dc.subjectFizik Tedavi, Spor Terapisi ve Rehabilitasyon
dc.subjectKayropraktik
dc.subjectRehabilitasyon
dc.subjectPhysical Therapy, Sports Therapy and Rehabilitation
dc.subjectChiropractics
dc.subjectRehabilitation
dc.subjectIntermittent hypoxia
dc.subjectcomplete blood count tests
dc.subjectanimal model
dc.titleThe effects of therapeutic intermittent hypoxia implementation on complete blood count parameters: an experimental animal model
dc.typearticle
dspace.entity.typePublication
local.avesis.ide13eefc1-ebc7-4318-8a70-8e4ab0df23e7
local.indexed.atTRDIZIN
relation.isAuthorOfPublication290efe89-ff1c-49a8-aae2-5a7b727f68a1
relation.isAuthorOfPublicationca6812f7-9b0e-4443-bdf4-8e8c2e949fd2
relation.isAuthorOfPublication8e72e84d-85d2-426b-a3f5-5d50987cdd8e
relation.isAuthorOfPublication.latestForDiscovery290efe89-ff1c-49a8-aae2-5a7b727f68a1

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