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Atypical presentation of medication-related osteonecrosis of the jaw in a young male patient undergoing chemotherapy for acute lymphoblastic leukemia

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dc.contributor.authorÖZKAN, YAŞAR
dc.contributor.authorBAYRAM, FERİT
dc.contributor.authorsBayram F., Fattahzade S., Uzay A., Özkan Y.
dc.date.accessioned2023-11-02T10:49:24Z
dc.date.available2023-11-02T10:49:24Z
dc.date.issued2023-12-01
dc.description.abstractThis case report aims to highlight the importance of close oral monitoring before and during chemotherapy in patients with B-cell acute lymphoblastic leukemia (B-ALL) to prevent medication-related osteonecrosis of the jaw (MRONJ). A 22-year-old male patient diagnosed with B-ALL who developed MRONJ during chemotherapy, despite not receiving bisphosphonates or denosumab, was presented. The patient\"s medical history, treatment regimen, clinical examination findings, and treatment outcomes were reported. The patient developed maxillofacial cellulitis during chemotherapy, leading to a diagnosis of stage 3 MRONJ. Conservative treatment was initiated, resulting in the reversion of the disease to stage 1 and stabilization of the progression. The patient achieved remission and underwent prophylactic cranial radiotherapy. This case report presents a unique case of MRONJ in a young patient without prior use of antiresorptive agents or denosumab. It highlights the need for close oral monitoring in patients with B-ALL before and during chemotherapy, as MRONJ can develop in the absence of these medications.
dc.identifier.citationBayram F., Fattahzade S., Uzay A., Özkan Y., "Atypical presentation of medication-related osteonecrosis of the jaw in a young male patient undergoing chemotherapy for acute lymphoblastic leukemia", Oral Oncology Reports, cilt.1, ss.1, 2023
dc.identifier.doi10.1016/j.oor.2023.100115
dc.identifier.endpage1
dc.identifier.issn2772-9060
dc.identifier.startpage1
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S277290602300105X
dc.identifier.urihttps://hdl.handle.net/11424/294581
dc.identifier.volume1
dc.language.isoeng
dc.relation.ispartofOral Oncology Reports
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectSağlık Bilimleri
dc.subjectHealth Sciences
dc.subjectKlinik Tıp (MED)
dc.subjectClinical Medicine (MED)
dc.subjectAcute lymphoblastic leukemia
dc.subjectChemotherapy drugs
dc.subjectMedication related osteonecrosis of the jaw
dc.titleAtypical presentation of medication-related osteonecrosis of the jaw in a young male patient undergoing chemotherapy for acute lymphoblastic leukemia
dc.typearticle
dspace.entity.typePublication
local.avesis.id029ff7e1-0e11-4010-939c-51ac5b60cee1
relation.isAuthorOfPublicatione103f67e-8279-44ff-a25d-d92c6ea9348c
relation.isAuthorOfPublication46bad1ec-9995-40c2-8753-f6a44577920b
relation.isAuthorOfPublication.latestForDiscoverye103f67e-8279-44ff-a25d-d92c6ea9348c

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