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Knowledge, opinions and attitudes of primary care physicians about generic drugs: a cross-sectional study

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dc.contributor.authorAKICI, AHMET
dc.contributor.authorsOncu, Seyma; Bayram, Dilara; Aydin, Volkan; Isli, Fatma; Aksoy, Mesil; Akici, Ahmet; Ucku, Reyhan; Gelal, Ayse
dc.date.accessioned2022-03-12T22:58:16Z
dc.date.available2022-03-12T22:58:16Z
dc.date.issued2021
dc.description.abstractBackground: Generic drug (GD) use is affected by many factors, including physicians' approach. Objective: This study aimed to investigate the knowledge, opinions and attitudes of primary care physicians (PCPs) about GDs and potentially associated factors. Methods: An adequately representative sample (n = 354) of PCPs was determined via stratified and simple random sample selection method in this descriptive, cross-sectional study.The research data were collected through a face-to-face 40-item survey, where the knowledge, opinions and attitudes about GDs were questioned. The prescribing percentage of GDs overall was also examined. Results: The survey was completed by 305 PCPs (mean age: 49.2 +/- 7.9 years; 57.4% male). The rate of correct responses about GDs was 67.6% for basic knowledge and 46.6% for the development process. The percentages of PCPs who declared that GDs were 'less efficacious', 'of lower quality' and 'less safe' than original drugs were 65.2%, 53.4% and 35.4%, respectively. More than half (60.3%) of the PCPs declared not to pay attention to whether the drug is generic while prescribing. It was observed that, as the knowledge level of the physicians increased, negative opinions and prescribing attitudes regarding the effectiveness, quality and safety of the GDs decreased.The rate of GD prescribing (51.6%) in Izmir was lower than the rest of the country (54.6%; P < 0.001). Conclusion: This study shows that the knowledge of PCPs about GDs is generally inadequate, which reflects negatively on their opinions and attitudes regarding the use of GDs. Educational activities can help establish awareness that GDs can be used without doubt of their effectiveness, quality and safety.
dc.identifier.doi10.1093/fampra/cmaa138
dc.identifier.eissn1460-2229
dc.identifier.issn0263-2136
dc.identifier.pubmed33340330
dc.identifier.urihttps://hdl.handle.net/11424/237165
dc.identifier.wosWOS:000693756900011
dc.language.isoeng
dc.publisherOXFORD UNIV PRESS
dc.relation.ispartofFAMILY PRACTICE
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectBioavailability
dc.subjectbioequivalence
dc.subjectfamily physicians
dc.subjectgeneric drug
dc.subjectknowledge
dc.subjectrational drug use
dc.subjectPERCEPTIONS
dc.titleKnowledge, opinions and attitudes of primary care physicians about generic drugs: a cross-sectional study
dc.typearticle
dspace.entity.typePublication
local.avesis.id1ddc3e25-0a9b-4c1d-a84b-3cb6c76b5016
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages8
oaire.citation.endPage279
oaire.citation.issue3
oaire.citation.startPage272
oaire.citation.titleFAMILY PRACTICE
oaire.citation.volume38
relation.isAuthorOfPublication6c7c9f26-63a9-4f6f-91cd-aa9e3452919c
relation.isAuthorOfPublication.latestForDiscovery6c7c9f26-63a9-4f6f-91cd-aa9e3452919c

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