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Epicardial Fat Tissue Thickness Correlates with Endothelial Dysfunction and Other Cardiovascular Risk Factors in Patients with Metabolic Syndrome

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dc.contributor.authorYAVUZ, DİLEK
dc.contributor.authorsAydin, Hasan; Toprak, Ahmet; Deyneli, Oguzhan; Yazici, Dilek; Tarcin, Oezlem; Sancak, Seda; Yavuz, Dilek; Akalin, Sema
dc.date.accessioned2022-03-12T17:49:07Z
dc.date.available2022-03-12T17:49:07Z
dc.date.issued2010
dc.description.abstractBackground: Epicardial adipose tissue has shown to be related to cardiovascular risk. The aim of this study is to investigate the relationship between epicardial adiposity and endothelial function in metabolic syndrome. Methods: Fifty patients with metabolic syndrome were recruited. Anthropometric measurements, fasting blood glucose, insulin, lipid profile, high-sensitivity C-reactive protein (hsCRP), fibrinogen, apolipoprotein A (Apo A), Apo B1, and lipoprotein (a) [Lp(a)] were determined. Homeostasis model assessment of insulin resistance (HOMA-IR) was calculated. Epicardial fat thickness was measured via two-dimensional M-mode echocardiography. Endothelial function was assessed as flow-mediated dilatation at the brachial artery. Results: Epicardial fat tissue thickness was shown to be correlated negatively with FMD and positively with age, diastolic blood pressure, hsCRP, fibrinogen, HOMA-IR, and lipid parameters. Multiple regression analysis showed epicardial fat tissue thickness to be an independent factor influencing the endothelial function. Conclusions: Epicardial fat tissue may be a useful parameter in the assessment of patients with metabolic syndrome.
dc.identifier.doi10.1089/met.2009.0080
dc.identifier.eissn1557-8518
dc.identifier.issn1540-4196
dc.identifier.pubmed20156077
dc.identifier.urihttps://hdl.handle.net/11424/230055
dc.identifier.wosWOS:000278322100007
dc.language.isoeng
dc.publisherMARY ANN LIEBERT, INC
dc.relation.ispartofMETABOLIC SYNDROME AND RELATED DISORDERS
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectADIPOSE-TISSUE
dc.subjectADIPONECTIN EXPRESSION
dc.subjectVISCERAL ADIPOSITY
dc.subjectDISEASE
dc.subjectOBESITY
dc.titleEpicardial Fat Tissue Thickness Correlates with Endothelial Dysfunction and Other Cardiovascular Risk Factors in Patients with Metabolic Syndrome
dc.typearticle
dspace.entity.typePublication
local.avesis.id6cb87b2b-02b7-4ce4-a3b2-f2ae26284354
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.journal.numberofpages6
oaire.citation.endPage234
oaire.citation.issue3
oaire.citation.startPage229
oaire.citation.titleMETABOLIC SYNDROME AND RELATED DISORDERS
oaire.citation.volume8
relation.isAuthorOfPublication26174ec5-7dca-4038-a7fe-9a43f236fd15
relation.isAuthorOfPublication.latestForDiscovery26174ec5-7dca-4038-a7fe-9a43f236fd15

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