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Changing treatment strategy of cavernous sinus meningiomas: experience of a single institution

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dc.contributor.authorBAYRAKLI, FATİH
dc.contributor.authorsPamir, MN; Kilic, T; Bayrakli, F; Peker, S
dc.date.accessioned2022-03-12T17:19:03Z
dc.date.available2022-03-12T17:19:03Z
dc.date.issued2005
dc.description.abstractBackground: Oncological treatment of a neoplasm is more than surgical removal of the tumor. Probably, this truth is the reason for the ongoing discussion on cavernous sinus meningiomas in the last decade. Debate on optimal management of cavernous sinus meningiomas aims to compare the different treatment strategies: (a) radical surgical resection and (b) conservative surgical resection complemented with radiosurgical treatment. Materials and Methods: Natural history of the change in the management strategy of cavernous sinus meningiomas in our department before and after GK facility became available in 1997 allowed us to compare the 2 aforementioned strategies. Before installation of a Leksell GK unit at the hospital in 1997, the neurosurgical team at Marmara University Institute of Neurological Sciences and Faculty of Medicine (Istanbul, Turkey) treated patients with cavernous sinus meningioma using radical resection (radical strategy, group A, 10 patients). After 1997, the same neurosurgical team used understanding of surgical removal of the extracavernous sinus tumor component with GK irradiation of the intracavernous part (conservative strategy, group B, 12 patients). Another group of patients, who were treated with GK as a first-step treatment, was analyzed (GK group, group C, 26 patients). Results: At the end of the third year, more stable tumor volume control was achieved in groups B and C; after the second year, an incline in the tumor volume-time graph was detected. Group B resulted in less cranial nerverelated complications; a certain degree of improvement in cranial nerve deficits was observed. Conclusion: Comparing 2 different management strategies for cavernous sinus meningiomas in the same hospital setting using the same neurosurgical group, we conclude that extracavernous resection followed by GK is as effective as radical surgery. Considering cranial nerve complications and third-year tumor volume control achievement, conservative approach yielded better results. Longer follow-up with larger series is necessary. (c) 2005 Elsevier Inc. All rights reserved.
dc.identifier.doi10.1016/j.surneu.2005.07.053
dc.identifier.issn0090-3019
dc.identifier.urihttps://hdl.handle.net/11424/228052
dc.identifier.wosWOS:000233321000012
dc.language.isoeng
dc.publisherELSEVIER SCIENCE INC
dc.relation.ispartofSURGICAL NEUROLOGY
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectmeningioma
dc.subjectradical resection
dc.subjectgamma knife irradiation
dc.subjectGAMMA-KNIFE RADIOSURGERY
dc.subjectGROWTH-FACTOR
dc.subjectFOLLOW-UP
dc.subjectMANAGEMENT
dc.subjectSURGERY
dc.subjectRECURRENCE
dc.subjectTUMORS
dc.subjectPROGRESSION
dc.subjectEXPRESSION
dc.subjectCHORDOMAS
dc.titleChanging treatment strategy of cavernous sinus meningiomas: experience of a single institution
dc.typearticle
dspace.entity.typePublication
local.avesis.id86f24532-7a9a-4c0d-941c-826a4655dbad
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages9
oaire.citation.endPage66
oaire.citation.startPage58
oaire.citation.titleSURGICAL NEUROLOGY
oaire.citation.volume64
relation.isAuthorOfPublicationf8075bc9-c8f2-4422-839e-ed73fb5796a9
relation.isAuthorOfPublication.latestForDiscoveryf8075bc9-c8f2-4422-839e-ed73fb5796a9

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