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Chemical Ablation for Treating Anal Fistulas without Surgical Intervention: Long-Term Results

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dc.contributor.authorKARA, BURAK
dc.contributor.authorsAttaallah, Wafi; Uprak, Tevfik K.; Kara, Burak; Sen, Aliosman; Tuney, Davut; Yegen, Cumhur
dc.date.accessioned2022-03-12T22:55:30Z
dc.date.available2022-03-12T22:55:30Z
dc.date.issued2021
dc.description.abstractPurposes. This study aimed to evaluate long-term outcomes after the application of a corrosive chemical agent for ablation of epithelial tissue as a non-surgical treatment of anal fistulas. Methods. Adult patients with symptomatic perianal fistula were prospectively included in the study. The fistula tract was irrigated with a 5% silver nitrate solution. The primary outcome measured in this study was the rate of clinical healing after long-term follow-up. Factors that may affect healing were also analysed. Results. A total of 186 patients with anal fistula were analysed. After irrigation with silver nitrate, 82 (44%) patients had complete clinical healing during a median follow-up time of 50 (7-64) months. Patients with intermittent discharge had a significantly higher rate of complete clinical healing than those with continuous discharge (P < .04). Fistulas without abscesses or secondary tracts had a significantly higher rate of complete clinical healing than the other types (P = .007). Conclusion. Chemical ablation of the epithelium of the anal fistula yields promising long-term outcomes in the management of anal fistulas without surgical intervention.
dc.identifier.doi10.1177/15533506211006080
dc.identifier.eissn1553-3514
dc.identifier.issn1553-3506
dc.identifier.pubmed33787391
dc.identifier.urihttps://hdl.handle.net/11424/236763
dc.identifier.wosWOS:000636010200001
dc.language.isoeng
dc.publisherSAGE PUBLICATIONS INC
dc.relation.ispartofSURGICAL INNOVATION
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectanal fistula
dc.subjectchemical ablation
dc.subjectlong term
dc.titleChemical Ablation for Treating Anal Fistulas without Surgical Intervention: Long-Term Results
dc.typearticle
dspace.entity.typePublication
local.avesis.id72e7a962-1039-4377-9646-59b36a56f099
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.journal.articlenumber1.55335062110061E+016
local.journal.numberofpages7
oaire.citation.endPage737
oaire.citation.issue6
oaire.citation.startPage731
oaire.citation.titleSURGICAL INNOVATION
oaire.citation.volume28
relation.isAuthorOfPublicationddf889bc-1e30-4a09-bb86-bfadf3e4bab7
relation.isAuthorOfPublication.latestForDiscoveryddf889bc-1e30-4a09-bb86-bfadf3e4bab7

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