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Er:YAG Laser Versus Systemic Metronidazole as an Adjunct to Nonsurgical Periodontal Therapy: A Clinical and Microbiological Study

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dc.contributor.authorKADİR, TANJU
dc.contributor.authorsYilmaz, Selcuk; Kut, Burak; Gursoy, Hare; Eren-Kuru, Bahar; Noyan, Ulku; Kadir, Tanju
dc.date.accessioned2022-03-12T18:06:13Z
dc.date.available2022-03-12T18:06:13Z
dc.date.issued2012
dc.description.abstractObjective: The objective of this randomized clinical trial was to describe the clinical and microbiological results obtained by treatment with Er:YAG laser and systemic metronidazole used as adjuncts to mechanical subgingival debridement in chronic periodontitis. Methods: Twenty-seven chronic periodontitis (CP) patients were randomly divided into three parallel groups each comprising nine individuals with at least four teeth having at least one approximal site with a probing depth (PD) of >= 5 mm and gingival index (GI) of >= 2 in each quadrant. Groups of patients received: (1) Scaling and root planing (SRP) + Er:YAG laser (10 hz, 30 mJ/pulse, 1 min per pocket, apico-coronal direction in parallel paths with 30 degree angle tips, under water irrigation), (2) SRP + systemic metronidazole, or (3) SRP alone. In all treatment groups, SRP was performed at 1 week intervals in two sessions. The microbiological and clinical effects of the treatments were evaluated after 90 days. Results: At the end of the experimental period, statistically significant improvements in plaque index, GI, PD and attachment level, as well as reductions in the number of total bacteria and proportions of obligately anaerobic microorganisms were observed within each group. Although intergroup comparisons revealed no significant microbiological differences, clinical parameters as attachment gain and PD reduction were found significantly higher in Group 1 compared with the other groups. Conclusions: Within its limits, this study demonstrated the possibility of better resolution of infection with combined SRP + Er: YAG laser treatment. However, microbiological results failed to demonstrate significant advantages of this combination in comparison with SRP alone or SRP + systemic metronidazole.
dc.identifier.doi10.1089/pho.2010.2762
dc.identifier.issn1549-5418
dc.identifier.pubmed22509738
dc.identifier.urihttps://hdl.handle.net/11424/230861
dc.identifier.wosWOS:000305284500006
dc.language.isoeng
dc.publisherMARY ANN LIEBERT INC
dc.relation.ispartofPHOTOMEDICINE AND LASER SURGERY
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectER-YAG LASER
dc.subjectHUMAN GINGIVAL FIBROBLASTS
dc.subjectUP SPLIT-MOUTH
dc.subjectINTERLEUKIN-1-BETA PRODUCTION
dc.subjectADULT PERIODONTITIS
dc.subjectROOT SURFACES
dc.subjectIN-VITRO
dc.subjectIRRADIATION
dc.subjectPROLIFERATION
dc.subjectINHIBITION
dc.titleEr:YAG Laser Versus Systemic Metronidazole as an Adjunct to Nonsurgical Periodontal Therapy: A Clinical and Microbiological Study
dc.typearticle
dspace.entity.typePublication
local.avesis.id9578e278-20bd-4da3-9c0d-403d2fb558ec
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.journal.numberofpages6
oaire.citation.endPage330
oaire.citation.issue6
oaire.citation.startPage325
oaire.citation.titlePHOTOMEDICINE AND LASER SURGERY
oaire.citation.volume30
relation.isAuthorOfPublicatione0ebf174-b3eb-48f5-9478-ae7c8a0747d8
relation.isAuthorOfPublication.latestForDiscoverye0ebf174-b3eb-48f5-9478-ae7c8a0747d8

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