Publication:
Acid proteinase, phospholipase and adherence properties of Candida parapsilosis strains isolated from clinical specimens of hospitalised patients

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dc.contributor.authorKARAVUŞ, MELDA
dc.contributor.authorsDagdeviren, M; Cerikcioglu, N; Karavus, M
dc.date.accessioned2022-03-12T17:19:22Z
dc.date.available2022-03-12T17:19:22Z
dc.date.issued2005
dc.description.abstractIn this study, we investigated the presence of virulence factors in a total of 33 Candida parapsilosis strains, including adherence, acid proteinase and phospholipase production capabilities. Of the 33 strains, 19 were isolated from blood cultures of hospitalised fungaemic patients (study group 2). We also investigated the importance of other factors present in the development of fungaemia. The mean adherence values of 19 blood isolates and 14 non-blood isolates were found to be 52.63 and 57.96, respectively; these values did not differ significantly (P > 0.05). Nine non-blood strains (64.29%) of study group 2 and five blood strains (26.31%) of study group 1 were found to be positive for acid proteinase production; this difference was statistically significant (P < 0.05). Phospholipase production was found in five strains (26.31%) of the 19 blood isolates. None of the 14 non-blood strains exhibited phospholipase activity; this difference between the two groups was statistically significant (P < 0.05). In this study, correlations between adherence-phospholipase, and adherence-acid proteinase properties of strains were detected as well. In the present study, it has been observed that phospholipase production can be an important virulence factor in bloodstream infections caused by C. parapsilosis.
dc.identifier.doi10.1111/j.1439-0507.2005.01145.x
dc.identifier.eissn1439-0507
dc.identifier.issn0933-7407
dc.identifier.pubmed16115102
dc.identifier.urihttps://hdl.handle.net/11424/228096
dc.identifier.wosWOS:000231284500004
dc.language.isoeng
dc.publisherWILEY
dc.relation.ispartofMYCOSES
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCandida parapsilosis
dc.subjectenzymes
dc.subjectproteinase
dc.subjectphospholipase
dc.subjectadherence
dc.subjectCELL-SURFACE HYDROPHOBICITY
dc.subjectBUCCAL EPITHELIAL-CELLS
dc.subjectALBICANS
dc.subjectPATHOGENICITY
dc.subjectEPIDEMIOLOGY
dc.subjectVIRULENCE
dc.subjectADHESION
dc.titleAcid proteinase, phospholipase and adherence properties of Candida parapsilosis strains isolated from clinical specimens of hospitalised patients
dc.typearticle
dspace.entity.typePublication
local.avesis.ide2b39a0a-badd-4ae6-bd40-d305fa848bba
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages6
oaire.citation.endPage326
oaire.citation.issue5
oaire.citation.startPage321
oaire.citation.titleMYCOSES
oaire.citation.volume48
relation.isAuthorOfPublicationc5c161d0-9867-4fa2-8a04-c8e6a3c66d28
relation.isAuthorOfPublication.latestForDiscoveryc5c161d0-9867-4fa2-8a04-c8e6a3c66d28

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