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Antihypertensive drug utilization at health centres in a district of Istanbul

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dc.contributor.authorAKICI, AHMET
dc.contributor.authorsAkici, Ahmet; Kalaca, Sibel; Ugurlu, Uemit; Toklu, Hale Z.; Oktay, Sule
dc.date.accessioned2022-03-12T17:32:39Z
dc.date.available2022-03-12T17:32:39Z
dc.date.issued2007
dc.description.abstractObjective: Since irrational use of antihypertensives has considerable clinical and economical consequences, this study was conducted to evaluate antihypertensive drug utilization in hypertension at seven State Health Centres in Istanbul. Method: A total of 297 hypertensive patients who accepted to participate in the study were evaluated by a face-to-face questionnaire and a copy of their prescriptions were collected for prescription analysis. Results: Angiotensin-converting enzyme (ACE) inhibitors (31.7%), calcium channel blockers (28.8%), diuretics (16.2%), beta blockers (7.5%) and others (15.8%) have been prescribed. There were no statistically significant relation between prescribed antihypertensive drug groups and gender, age, and NSAIDs co-prescribing. The most frequent comorbidity in hypertensive patients was diabetes mellitus (10.4%) and calcium channel blockers (35.5%) have been prescribed to them as a first antihypertensive medication. Average cost per prescription was $42.7 +/- 38.1. According to the patients' self-reporting, the majority of them (85%) were prescribed without a physical examination. The physicians failed to write the prescriptions appropriately; only 5% of the scripts contained all information about the drug(s) and use instructions in full format. Conclusion: The present study indicates that GPs working at primary healthcare centres were rational in terms of antihypertensive drug choice. However, they poorly applied rational pharmacotherapy principles such as (a) writing a good prescription which is easily readable by the pharmacist and the patient and that contains full essential information; (b) a medical examination of the patient to assess her/his current clinical condition; and (c) taking care of not prescribing drugs with potential interaction like antihypertensives and NSAIDs together.
dc.identifier.doi10.1007/s11096-007-9103-5
dc.identifier.eissn1573-739X
dc.identifier.issn0928-1231
dc.identifier.pubmed17333494
dc.identifier.urihttps://hdl.handle.net/11424/228652
dc.identifier.wosWOS:000247682900004
dc.language.isoeng
dc.publisherSPRINGER
dc.relation.ispartofPHARMACY WORLD & SCIENCE
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjecthypertension
dc.subjectprescription
dc.subjectrational pharmacotherapy
dc.subjectgeneral practitioner
dc.subjectTurkey
dc.subjectantihypertensives
dc.subjectGENERAL-PRACTITIONERS
dc.subjectRATIONAL PHARMACOTHERAPY
dc.subjectBLOOD-PRESSURE
dc.subjectHYPERTENSION
dc.subjectIMPACT
dc.subjectMANAGEMENT
dc.subjectPHYSICIANS
dc.subjectBLOCKERS
dc.titleAntihypertensive drug utilization at health centres in a district of Istanbul
dc.typearticle
dspace.entity.typePublication
local.avesis.id671e7789-bd63-4372-8c65-7233830731de
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages6
oaire.citation.endPage121
oaire.citation.issue3
oaire.citation.startPage116
oaire.citation.titlePHARMACY WORLD & SCIENCE
oaire.citation.volume29
relation.isAuthorOfPublication6c7c9f26-63a9-4f6f-91cd-aa9e3452919c
relation.isAuthorOfPublication.latestForDiscovery6c7c9f26-63a9-4f6f-91cd-aa9e3452919c

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