Publication:
Synaptic organization of the rat thalamus: a quantitative study

Simple item page
dc.contributor.authorONAT, FİLİZ
dc.contributor.authorsCavdar, Safiye; Hacioglu, Husniye; Sirvanci, Serap; Keskinoz, Elif; Onat, Filiz
dc.date.accessioned2022-03-12T17:50:38Z
dc.date.available2022-03-12T17:50:38Z
dc.date.issued2011
dc.description.abstractFirst-order thalamic nuclei receive driving afferents from ascending pathways and transmit processed information to the cortex. Higher-order thalamic nuclei receive driver messages from layer 5 of cortex and transmit information from one cortical area to the other. The different types of axon terminals RL (round vesicles, large terminals), RS (round vesicles, small terminals) and F (flattened vesicles) and their synaptic junctions have been here compared in three first-order (ventrobasal, lateral geniculate and anteroventral) and three higher-order (posterior, lateral posterior and mediodorsal) thalamic nuclei of the rat. In the present study, the higher-order relays differ from first-order relays as in the cat, in having fewer driver terminals (RL) and synapses than do the first-order relays. However, the F terminals showed opposite ratios in the first versus higher-order thalamic nuclei. The majority of the terminals in all thalamic nuclei studied were RS terminals. The area measurements of the three types of terminals and synaptic lengths showed no significant differences between first and higher-order nuclei. The driver inputs represent the minority and the modulatory inputs represent the majority of the terminals and synapses in all thalamic nuclei. In conclusion, there is a relative paucity of driver inputs, whereas modulatory inputs establish more numerous synapses to achieve finer modulation.
dc.identifier.doi10.1007/s10072-011-0606-4
dc.identifier.eissn1590-3478
dc.identifier.issn1590-1874
dc.identifier.pubmed21544663
dc.identifier.urihttps://hdl.handle.net/11424/230197
dc.identifier.wosWOS:000297546800007
dc.language.isoeng
dc.publisherSPRINGER-VERLAG ITALIA SRL
dc.relation.ispartofNEUROLOGICAL SCIENCES
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectGABA immunostaining
dc.subjectElectron microscopy
dc.subjectDrivers
dc.subjectModulators
dc.subjectLATERAL GENICULATE-NUCLEUS
dc.subjectHIGHER-ORDER
dc.subjectCORTICOTHALAMIC PROJECTIONS
dc.subjectRETICULAR NUCLEUS
dc.subjectPHA-L
dc.subjectCORTICOCORTICAL COMMUNICATION
dc.subjectGABAERGIC INTERNEURONS
dc.subjectSOMATOSENSORY THALAMUS
dc.subjectRELATIVE DISTRIBUTION
dc.subjectANTEROGRADE TRACER
dc.titleSynaptic organization of the rat thalamus: a quantitative study
dc.typearticle
dspace.entity.typePublication
local.avesis.idfaec29e5-687b-4613-934a-f2d4b62b5514
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.journal.numberofpages10
oaire.citation.endPage1056
oaire.citation.issue6
oaire.citation.startPage1047
oaire.citation.titleNEUROLOGICAL SCIENCES
oaire.citation.volume32
relation.isAuthorOfPublicationc359dea3-046f-4397-90d5-62e4bfc31869
relation.isAuthorOfPublication.latestForDiscoveryc359dea3-046f-4397-90d5-62e4bfc31869

Files

Collections

Research Outputs