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Acute megakaryoblastic leukemia mimicking small round cell tumor with novel t(1;5)(q21;p13)

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dc.contributor.authorBOZKURT, SÜHEYLA
dc.contributor.authorsBozkurt, Suheyla Uyar; Berrak, Su Gulsun; Tugtepe, Halil; Canpolat, Cengiz; Palanduz, Sukru; Tecimer, Tulay
dc.date.accessioned2022-03-12T17:34:21Z
dc.date.available2022-03-12T17:34:21Z
dc.date.issued2008
dc.description.abstractAcute megakaryoblastic leukemia is a relatively rare form of acute leukemia that has heterogeneous blast morphology and karyotypic abnormalities. An 8-month-old boy with a retroperitoneal mass was diagnosed as having acute megakaryoblastic leukemia that initially presented as small round cell tumor of childhood. Bone marrow aspiration showed syncytial groups of atypical medium sized cells with scant cytoplasm and fine nuclear chromatin. Retroperitoneal mass biopsy showed several lymph nodes with cohesive clusters of neoplastic cells that demonstrated expression of Factor VIII. Flow cytometric analysis of the second bone marrow aspiration showed CD 61 positivity. Karyotypic analysis of bone marrow cells showed a novel translocation, (1;5)(q21;p13).
dc.identifier.doi10.1111/j.1600-0463.2008.00780.x
dc.identifier.issn0903-4641
dc.identifier.pubmed18321370
dc.identifier.urihttps://hdl.handle.net/11424/229009
dc.identifier.wosWOS:000253757200013
dc.language.isoeng
dc.publisherBLACKWELL PUBLISHING
dc.relation.ispartofAPMIS
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectacute megakaryoblastic leukemia
dc.subjectsmall round cell tumor
dc.subjectmetastatic carcinoma
dc.subjectcytogenetics
dc.subjectt(1;5)
dc.subjectSIMULATING METASTATIC TUMOR
dc.subjectTRANSLOCATION
dc.subjectCHILDREN
dc.subjectINFANTS
dc.subjectGENE
dc.titleAcute megakaryoblastic leukemia mimicking small round cell tumor with novel t(1;5)(q21;p13)
dc.typearticle
dspace.entity.typePublication
local.avesis.idc2eb7c58-de11-4002-8302-ba22daeeb2a4
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages4
oaire.citation.endPage166
oaire.citation.issue2
oaire.citation.startPage163
oaire.citation.titleAPMIS
oaire.citation.volume116
relation.isAuthorOfPublicationdd039cf9-dfb8-4af0-b879-0b88c3a852fa
relation.isAuthorOfPublication.latestForDiscoverydd039cf9-dfb8-4af0-b879-0b88c3a852fa

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