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Health-related quality of life assessed by LupusQoL questionnaire and SF-36 in Turkish patients with systemic lupus erythematosus

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dc.contributor.authorDİRESKENELİ, RAFİ HANER
dc.contributor.authorsYilmaz-Oner, Sibel; Oner, Can; Dogukan, Fatih Mert; Moses, Toklong Filam; Demir, Kubra; Tekayev, Nazar; Atagunduz, Pamir; Tuglular, Serhan; Direskeneli, Haner
dc.date.accessioned2022-03-12T20:28:20Z
dc.date.available2022-03-12T20:28:20Z
dc.date.issued2016
dc.description.abstractThe LupusQoL is a disease-specific health-related quality of life (HRQoL) measure for patients with lupus. We conducted this study to compare the efficiency of LupusQoL-TR (validated Turkish version of the LupusQoL questionnaire) with the 36-item Short-Form Health Survey (SF-36), a generic quality of life (QoL) scale, in Turkish patients with lupus. Both questionnaires were conducted at a single visit to the clinic. Disease activity was measured with the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI). Associations between the LupusQoL-TR and SF-36 domains were examined while also examining age, disease duration, and disease activity for each questionnaire. Descriptive statistics, Spearman's correlation coefficients, and Students t test were performed to analyze the data. A total of 113 consecutive patients with lupus (F/M 108:5, mean age 40.6 +/- 11.9 years, mean disease duration 8.5 +/- 7.0 years) were included, and 69 % of these were active. The median SLEDAI score was 2 (0-24), the mean global LupusQoL-TR score was 60.9 +/- 23.3, and the mean SF-36 score was 41.2 +/- 9.0. There was a significant correlation between LupusQoL-TR and SF-36 mean scores (r = 0.83; p < 0.001). QoL assessed by LupusQoL-TR and SF-36 did not correlate with disease activity (r = -0.11; p = 0.244 and r = -0.03; p = 0.721, respectively). LupusQoL-TR and SF-36 questionnaires were beneficial instruments in evaluating HRQoL in Turkish lupus patients. However, LupusQoL-TR and SF-36 were not associated with SLEDAI scores, which suggested that QoL might be affected by other factors besides disease activity, especially in clinically inactive or mildly active patients.
dc.identifier.doi10.1007/s10067-015-2930-1
dc.identifier.eissn1434-9949
dc.identifier.issn0770-3198
dc.identifier.pubmed25846834
dc.identifier.urihttps://hdl.handle.net/11424/233894
dc.identifier.wosWOS:000372429000007
dc.language.isoeng
dc.publisherSPRINGER LONDON LTD
dc.relation.ispartofCLINICAL RHEUMATOLOGY
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectLupusQoL-TR
dc.subjectQuality of life
dc.subjectSF-36
dc.subjectSystemic lupus erythematosus
dc.subjectDISEASE-ACTIVITY
dc.subjectVALIDATION
dc.subjectIMPACT
dc.subjectSLE
dc.titleHealth-related quality of life assessed by LupusQoL questionnaire and SF-36 in Turkish patients with systemic lupus erythematosus
dc.typearticle
dspace.entity.typePublication
local.avesis.idad0b7084-98c8-49ee-80b7-7d131608edb0
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages6
local.journal.quartileQ3
oaire.citation.endPage622
oaire.citation.issue3
oaire.citation.startPage617
oaire.citation.titleCLINICAL RHEUMATOLOGY
oaire.citation.volume35
relation.isAuthorOfPublication07a34d26-21f3-475d-bd36-152d6c659370
relation.isAuthorOfPublication.latestForDiscovery07a34d26-21f3-475d-bd36-152d6c659370

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