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Assessment of left atrial volume and function in patients with psoriasis by using real time three-dimensional echocardiography

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dc.contributor.authorÇİNÇİN, AHMET ALTUĞ
dc.contributor.authorsAtas, Halil; Kepez, Alper; Bozbay, Mehmet; Gencosmanoglu, Dilek Seckin; Cincin, Altug; Sunbul, Murat; Bozbay, Ayfer Yildiz; Darvishova, Ramila; Ergun, Tulin
dc.date.accessioned2022-03-13T12:49:54Z
dc.date.available2022-03-13T12:49:54Z
dc.date.issued2015
dc.description.abstractBackground Left atrial (LA) volume has been identified as a predictor of adverse cardiovascular outcomes, both in the general population and in selected clinical conditions. The aim of this study was to evaluate the effect of psoriasis on LA volume and mechanical function. Methods A total of 40 consecutive normotensive psoriasis patients free of any cardiovascular disease and 39 healthy volunteers were included. All participants underwent comprehensive transthoracic echocardiographic examination. LA volume and mechanical function were evaluated using real-time three-dimensional echocardiography (RT3DE). Results There were no significant differences between psoriasis and control groups with regard to conventional echocardiographic parameters. Individuals with psoriasis had a higher incidence of left ventricular diastolic dysfunction (LVDD) than the controls; nine people with psoriasis (23 %) and three control individuals (8 %) had LVDD (p = 0.06). With regard to the parameters obtained from RT3DE, LA maximum, LA minimum, passive stroke volume, and passive emptying fraction were significantly higher; whereas LA active emptying fraction, LA total emptying fraction, LA expansion index, and active stroke volume values were significantly lower in individuals with psoriasis compared with controls. Disease duration and Psoriasis Area of Severity Index (PASI) score correlated with the majority of volume parameters. Conclusion Individuals with psoriasis had higher LA phasic volumes and impaired LA mechanical function compared with healthy controls. LA volume and functional analysis with RT3DE may facilitate recognition of subtle LA dysfunction in patients with psoriasis.
dc.identifier.doi10.1007/s00508-015-0817-4
dc.identifier.eissn1613-7671
dc.identifier.issn0043-5325
dc.identifier.pubmed26227800
dc.identifier.urihttps://hdl.handle.net/11424/238321
dc.identifier.wosWOS:000365198700004
dc.language.isoeng
dc.publisherSPRINGER WIEN
dc.relation.ispartofWIENER KLINISCHE WOCHENSCHRIFT
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectPsoriasis
dc.subjectReal-time three-dimensional echocardiography
dc.subjectLeft atrial volume
dc.subjectLeft atrial mechanical function
dc.subjectLeft atrial contractility
dc.subjectVENTRICULAR DIASTOLIC FUNCTION
dc.subjectC-REACTIVE PROTEIN
dc.subjectDISEASE
dc.subjectINFLAMMATION
dc.subjectASSOCIATION
dc.titleAssessment of left atrial volume and function in patients with psoriasis by using real time three-dimensional echocardiography
dc.typearticle
dspace.entity.typePublication
local.avesis.id6b22a16a-c014-4127-b987-4475d3060e53
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages6
oaire.citation.endPage863
oaire.citation.issue21-22
oaire.citation.startPage858
oaire.citation.titleWIENER KLINISCHE WOCHENSCHRIFT
oaire.citation.volume127
relation.isAuthorOfPublication54255a29-54c0-43de-8bc5-39d805d1296a
relation.isAuthorOfPublication.latestForDiscovery54255a29-54c0-43de-8bc5-39d805d1296a

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