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Waist circumference is associated with carotid intima media thickness in peritoneal dialysis patients

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dc.contributor.authorVELİOĞLU, ARZU
dc.contributor.authorsAsicioglu, Ebru; Kahveci, Arzu; Arikan, Hakki; Koc, Mehmet; Tuglular, Serhan; Ozener, Cetin Ishak
dc.date.accessioned2022-03-12T18:08:33Z
dc.date.available2022-03-12T18:08:33Z
dc.date.issued2013
dc.description.abstractAtherosclerosis is responsible for the high mortality rate in end-stage renal disease patients. Defining risk factors for atherosclerosis may lead to reduction in cardiovascular disease through modification of these factors. Peritoneal dialysis (PD) patients are subjected to high glucose loads on a daily basis, which results in considerable weight gain and an increase in waist circumference (WC). WC as an indicator of abdominal obesity is a risk factor for atherosclerosis in the general population. Carotid artery intima media thickness (CIMT) measurement is a reliable method for the detection of early atherosclerosis. The aim of this study was to investigate the relationship between WC and CIMT and to define risk factors associated with CIMT in PD patients. Fifty-five PD patients and 40 healthy controls were included. Atherosclerosis was assessed using measurement of CIMT. Fasting blood was collected for analysis. Anthropometric parameters (age, weight, BMI, and WC) were measured. Peritoneal dialysis patients had higher WC (93.9 +/- A 1.7 vs. 87.3 +/- A 1.2 cm, p < 0.05) and CIMT (0.70 +/- A 0.02 vs. 0.57 +/- A 0.01 mm, p < 0.01) than the control group. On univariate analysis, age, WC, plaque formation, and D/P creatinine were positively correlated with CIMT, whereas residual renal function, albumin, ultrafiltration volume, and D/D0 glucose were negatively correlated. On multivariate analysis, only age, WC, and plaque formation showed correlation (p < 0.001). Carotid artery intima media thickness is associated with age, plaque formation, and WC in PD patients. WC measurement is a simple, inexpensive, reproducible, and reliable method of evaluating atherosclerosis risk in PD patients and should be assessed at every visit. Appropriate counsel should be provided to patients with greater WC who are deemed to be at risk for atherosclerosis.
dc.identifier.doi10.1007/s11255-013-0427-x
dc.identifier.eissn1573-2584
dc.identifier.issn0301-1623
dc.identifier.pubmed23553275
dc.identifier.urihttps://hdl.handle.net/11424/231167
dc.identifier.wosWOS:000325696900023
dc.language.isoeng
dc.publisherSPRINGER
dc.relation.ispartofINTERNATIONAL UROLOGY AND NEPHROLOGY
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAtherosclerosis
dc.subjectCarotid intima media thickness
dc.subjectPeritoneal dialysis
dc.subjectWaist circumference
dc.subjectC-REACTIVE PROTEIN
dc.subjectVISCERAL FAT
dc.subjectRISK-FACTORS
dc.subjectCORONARY
dc.subjectDISEASE
dc.subjectATHEROSCLEROSIS
dc.subjectCOMMON
dc.subjectHOMOCYSTEINE
dc.subjectMORTALITY
dc.subjectPLAQUE
dc.titleWaist circumference is associated with carotid intima media thickness in peritoneal dialysis patients
dc.typearticle
dspace.entity.typePublication
local.avesis.id4bcdb5fc-4e81-446f-92d4-48478955a117
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages7
oaire.citation.endPage1443
oaire.citation.issue5
oaire.citation.startPage1437
oaire.citation.titleINTERNATIONAL UROLOGY AND NEPHROLOGY
oaire.citation.volume45
relation.isAuthorOfPublicationa7410f0e-0eb4-4b83-ad61-a71dfbee164f
relation.isAuthorOfPublication.latestForDiscoverya7410f0e-0eb4-4b83-ad61-a71dfbee164f

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