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Quality of life and related factors among chronic hepatitis B-infected patients: a multi-center study, Turkey

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dc.contributor.authorTİGEN, ELİF
dc.contributor.authorsKaracaer, Zehra; Cakir, Banu; Erdem, Hakan; Ugurlu, Kenan; Durmus, Gul; Ince, Nevin Koc; Ozturk, Cinar; Hasbun, Rodrigo; Batirel, Ayse; Yilmaz, Esmeray Mutlu; Bozkurt, Ilkay; Sunbul, Mustafa; Aynioglu, Aynur; Atilla, Aynur; Erbay, Ayse; Inci, Ayse; Kader, Cigdem; Tigen, Elif Tukenmez; Karaahmetoglu, Gokhan; Coskuner, Seher Ayten; Dik, Ebru; Tarakci, Huseyin; Tosun, Selma; Korkmaz, Fatime; Kolgelier, Servet; Karadag, Fatma Yilmaz; Erol, Serpil; Turker, Kamuran; Necan, Ceyda; Sahin, Ahmet Melih; Ergen, Pinar; Iskender, Gulsen; Korkmaz, Pinar; Eroglu, Esma Gulesen; Durdu, Yasemin; Ulug, Mehmet; Deniz, Suna Secil; Koc, Filiz; Alpat, Saygin Nayman; Oztoprak, Nefise; Evirgen, Omer; Sozen, Hamdi; Dogan, Mustafa; Kaya, Selcuk; Kaya, Safak; Altindis, Mustafa; Aslan, Emel; Tekin, Recep; Sezer, Busra Ergut; Ozdemir, Kevser; Ersoz, Gulden; Sahin, Ahmet; Celik, Ilhami; Aydin, Emsal; Bastug, Aliye; Harman, Rezan; Ozkaya, Hacer Deniz; Parlak, Emine; Yavuz, Ilknur; Sacar, Suzan; Comoglu, Senol; Yenilmez, Ercan; Sirmatel, Fatma; Balkan, Ilker Inanc; Alpay, Yesim; Hatipoglu, Mustafa; Denk, Affan; Senol, Gunes; Bitirgen, Mehmet; Geyik, Mehmet Faruk; Guner, Rahmet; Kadanali, Ayten; Karakas, Ahmet; Namiduru, Mustafa; Udurgucu, Hatice; Boluktas, Rukiye Pinar; Karagoz, Ergenekon; Ormeci, Necati
dc.date.accessioned2022-03-14T08:16:03Z
dc.date.available2022-03-14T08:16:03Z
dc.date.issued2016-12
dc.description.abstractBackground: The aim of this study was to assess health-related quality of life (HRQOL) among chronic hepatitis B (CHB) patients in Turkey and to study related factors. Methods: This multicenter study was carried out between January 01 and April 15, 2015 in Turkey in 57 centers. Adults were enrolled and studied in three groups. Group 1: Inactive HBsAg carriers, Group 2: CHB patients receiving antiviral therapy, Group 3: CHB patients who were neither receiving antiviral therapy nor were inactive HBsAg carriers. Study data was collected by face-to-face interviews using a standardized questionnaire, Short Form-36 (SF-36) and Hepatitis B Quality of Life (HBQOL). Values equivalent to p < 0.05 in analyses were accepted as statistically significant. Results: Four thousand two hundred fifty-seven patients with CHB were included in the study. Two thousand five hundred fifty-nine (60.1 %) of the patients were males. Groups 1, 2 and 3, consisted of 1529 (35.9 %), 1721 (40.4 %) and 1007 (23.7 %) patients, respectively. The highest value of HRQOL was found in inactive HBsAg carriers. We found that total HBQOL score increased when antiviral treatment was used. However, HRQOL of CHB patients varied according to their socio-demographic properties. Regarding total HBQOL score, a higher significant level of HRQOL was determined in inactive HBV patients when matched controls with the associated factors were provided. Conclusions: The HRQOL score of CHB patients was higher than expected and it can be worsen when the disease becomes active. Use of an antiviral therapy can contribute to increasing HRQOL of patients.
dc.identifier.doi10.1186/s12955-016-0557-9
dc.identifier.issn1477-7525
dc.identifier.pubmed27809934
dc.identifier.urihttps://hdl.handle.net/11424/241351
dc.identifier.wosWOS:000386954300001
dc.language.isoeng
dc.publisherBMC
dc.relation.ispartofHEALTH AND QUALITY OF LIFE OUTCOMES
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectChronic hepatitis B infection
dc.subjectQuality of life
dc.subjectThe Hepatitis B Quality of Life Instrument
dc.subjectTurkey
dc.subjectMARITAL-STATUS
dc.subjectHEALTH
dc.subjectCOMORBIDITIES
dc.subjectIMPACT
dc.subjectDETERMINANTS
dc.subjectUTILITIES
dc.titleQuality of life and related factors among chronic hepatitis B-infected patients: a multi-center study, Turkey
dc.typearticle
dspace.entity.typePublication
local.avesis.id567bd555-b4ce-421c-a65d-5d98ddcb2ee0
local.import.packageSS16
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.articlenumber153
local.journal.numberofpages10
local.journal.quartileQ2
oaire.citation.titleHEALTH AND QUALITY OF LIFE OUTCOMES
oaire.citation.volume14
relation.isAuthorOfPublicationfad8e847-d87e-49b7-ad74-3ff14b50ed24
relation.isAuthorOfPublication.latestForDiscoveryfad8e847-d87e-49b7-ad74-3ff14b50ed24

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