Publication:
The relation of microbiologic data to aspartate aminotransferase enzyme activity in gingival crevicular fluid

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dc.contributor.authorYILMAZ, SEBİHA NİHAL
dc.contributor.authorKADİR, TANJU
dc.contributor.authorsKuru B., Noyan U., YILMAZ S. N., KADİR T., Acar O., Büget E.
dc.date.accessioned2023-07-07T08:58:42Z
dc.date.available2023-07-07T08:58:42Z
dc.date.issued1996-01-01
dc.description.abstractGingival crevicular fluid (GCF), reflects the immune and inflammatory reactions and is itself a location for specific host-microbe interactions that lead to periodontal diseases. Aspartate aminotransferase (AST) is one of the components of GCF that is released as a result of cell death. In this study, 40 periodontal sites in 10 early onset periodontitis patients before and after nonsurgical periodontal therapy, with and without local metronidazole administration, were first examined for the AST enzyme levels in GCF and then evaluated for microbiological and clinical variables. In each patient, 4 sites (one site/quadrant) with a probing depth of > or = 5 mm were selected and treated with separate treatment protocols. Certain microbial species including Prevotella intermedia, Porphyromonas gingivalis, and Actinobacillus actinomycetemcomitans(A. a.) were found more often and/or in higher levels in AST active sites (36/40 first measurement--9/36 second measurement), while other species (Streptococcus and Actinomyces) were found more often and/or in higher levels in AST inactive sites (4/40 first measurement--8/36 second measurement). Eight post-treatment AST active sites revealed 1.5 mm of attachment loss, whereas 8 post-treatment AST inactive sites showed 1.37 mm of attachment gain. AST activity and microbiological-clinical data presenting such an agreement suggests that, AST level assessment would be beneficial as an adjunctive method alongside other clinical criteria, in guiding the clinician in periodontal treatment.
dc.identifier.citationKuru B., Noyan U., YILMAZ S. N., KADİR T., Acar O., Büget E., "The relation of microbiologic data to aspartate aminotransferase enzyme activity in gingival crevicular fluid.", Journal of Marmara University Dental Faculty, cilt.2, sa.2-3, ss.491-499, 1996
dc.identifier.endpage499
dc.identifier.issn1018-5992
dc.identifier.issue2-3
dc.identifier.startpage491
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0030223673&origin=inward
dc.identifier.urihttps://hdl.handle.net/11424/290908
dc.identifier.volume2
dc.language.isoeng
dc.relation.ispartofJournal of Marmara University Dental Faculty
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectTemel Tıp Bilimleri
dc.subjectMedicine
dc.subjectHealth Sciences
dc.subjectFundamental Medical Sciences
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectTIP, GENEL & DAHİLİ
dc.subjectClinical Medicine (MED)
dc.subjectCLINICAL MEDICINE
dc.subjectMEDICINE, GENERAL & INTERNAL
dc.subjectGenel Tıp
dc.subjectGeneral Medicine
dc.titleThe relation of microbiologic data to aspartate aminotransferase enzyme activity in gingival crevicular fluid
dc.typearticle
dspace.entity.typePublication
local.avesis.ida14ee8c9-1d18-4ffd-a5d6-8163cb1b0b61
local.indexed.atPUBMED
local.indexed.atSCOPUS
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relation.isAuthorOfPublicatione0ebf174-b3eb-48f5-9478-ae7c8a0747d8
relation.isAuthorOfPublication.latestForDiscoverye3ccc709-73d9-45b3-a1d6-89e7f4b92427

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