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A Case of Acute Myeloid Leukemia (FAB M2) with Inversion 16 Who Presented with Pelvic Myeloid Sarcoma

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dc.contributor.authorKOÇ, AHMET
dc.contributor.authorsÇakan, Mustafa; Koç, Ahmet; Cerit, Kıvılcım; Bozkurt, Süheyla; Ergelen, Rabia; Vural, Irmak
dc.date.accessioned2022-03-14T04:31:44Z
dc.date.available2022-03-14T04:31:44Z
dc.date.issued2014
dc.description.abstractAcute leukemias are the most common childhood cancer in all age groups. Acute myeloid leukemias (AML) constitute about 15-20% of acute leukemias. Fatigability, pallor, fever, and bleeding are the most common presenting symptoms of AML. Hepatosplenomegaly and lymphadenopathy are commonly encountered during physical examination. In rare instances eruptions due to skin involvement and localized tumor masses (myeloid sarcoma) may be found. Myeloid sarcoma is especially seen in AML-M2 subtype. By cytogenetic analysis, in AML-M2 subtype t(8;21) is often seen and it is more probable to find inversion 16 in AML-M4Eos subtype. Herein, we present a 15-year-old girl whose initial symptom was abdominal pain for three days and her pathological sign was a large abdominal mass which was verified by imaging studies and diagnosed as myeloid sarcoma by biopsy. On bone marrow examination, she had diagnosis of AML-M2 and by cytogenetic analysis inversion 16 was positive. She was treated with AML-BFM 2004 protocol and she is being followed up in remission on her ninth month of the maintenance therapy.
dc.identifier.doi10.1155/2014/246169
dc.identifier.issn2090-6803
dc.identifier.pubmedPMID: 25610688 PMCID: PMC4283287
dc.identifier.urihttps://hdl.handle.net/11424/239083
dc.language.isoeng
dc.relation.ispartofCase Reports in Pediatrics
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleA Case of Acute Myeloid Leukemia (FAB M2) with Inversion 16 Who Presented with Pelvic Myeloid Sarcoma
dc.typearticle
dspace.entity.typePublication
local.avesis.ideac9afe8-bae9-4dec-9f6a-ed32225d7ec5
local.import.packageSS18
local.import.sourcePubMed
local.indexed.atPUBMED
oaire.citation.startPage246169
oaire.citation.titleCase Reports in Pediatrics
relation.isAuthorOfPublication41bfa1f1-f3ed-4d4b-9e02-902fd20bc830
relation.isAuthorOfPublication.latestForDiscovery41bfa1f1-f3ed-4d4b-9e02-902fd20bc830

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