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Phenolic composition and biological properties of Achillea nobilis L. subsp neilreichii (Kerner) Formanek

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dc.contributor.authorRAYAMAN, ERKAN
dc.contributor.authorsTaskin, Duygu; Taskin, Turgut; Rayaman, Erkan
dc.date.accessioned2022-03-12T22:25:52Z
dc.date.available2022-03-12T22:25:52Z
dc.date.issued2018
dc.description.abstractAchillea species are widely distributed medicinal plant throughout the world and have been used since ancient time. There are many reports about the traditional use and highly bioactive compounds of these plants. Therefore, it is fundamental to study in detail the chemical composition and biological activities of Achillea species. Thus, the objective of this study was to determine for the first time the effects of methods/solvents on biological activities (antioxidant, antimicrobial, and anti-urease) of Achillea nobilis L.subsp. neilreichii (Kerner) Formanek 15 extracts obtained from different extraction methods/solvents and then to analysis the phenolic contents of the active extracts. The phenolic contents in ethyl acetate and ethanol extracts, which showed strongest phenolic contents and antioxidant activity were analysed separately by high-performance liquid chromatography with diode array detection and were confirmed by liquid chromatography with quadrupole time-of-flight mass spectrometry using targeted mass spectra techniques with accurate mass. The active phenolic compounds were identified as dicaffeoylquinic acid, luteolin-7-O-glucoside, orientin, vitexin, luteolin, quercetin-methyl-ether, isorhamnetin-glucoside in ethyl acetate extract; chlorogenic acid luteolin-7-O-glucoside, quercetin-methyl-ether, luteolin, orientin, vitexin, dicaffeoylquinic acid, apigenin-6,8-di-C-glucoside, luteolin hexoside hexoside in ethanol extract. As a result of this study, dicaffeoylquinic acid, isorhamnetin-glucoside, chlorogenic acid, and apigenin-6,8-di-C-glucoside compounds were analysed for the first time in Achillea nobilis L. subsp. neilreichii (Kerner) Formanek. Therefore, it is thought that ethanol and ethyl acetate extracts can be used as a natural source in the future for food and pharmaceutical industry.
dc.identifier.doi10.1016/j.indcrop.2017.11.022
dc.identifier.eissn1872-633X
dc.identifier.issn0926-6690
dc.identifier.urihttps://hdl.handle.net/11424/234979
dc.identifier.wosWOS:000419407600068
dc.language.isoeng
dc.publisherELSEVIER
dc.relation.ispartofINDUSTRIAL CROPS AND PRODUCTS
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectA. nobilis L. subsp neilreichii (Kerner) Formanek
dc.subjectAntioxidant
dc.subjectAnti-urease
dc.subjectAntimicrobial
dc.subjectHPLC-DAD-MS
dc.subjectLIQUID-CHROMATOGRAPHY
dc.subjectANTIOXIDANT ACTIVITY
dc.subjectEXTRACT
dc.subjectUREASE
dc.subjectPLANTS
dc.titlePhenolic composition and biological properties of Achillea nobilis L. subsp neilreichii (Kerner) Formanek
dc.typearticle
dspace.entity.typePublication
local.avesis.id81f0eee2-1a62-4c54-aafe-3a0046cd9219
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.journal.numberofpages8
local.journal.quartileQ1
oaire.citation.endPage562
oaire.citation.startPage555
oaire.citation.titleINDUSTRIAL CROPS AND PRODUCTS
oaire.citation.volume111
relation.isAuthorOfPublication0f89f9f8-5aa4-40cc-a61f-030fd5328d19
relation.isAuthorOfPublication.latestForDiscovery0f89f9f8-5aa4-40cc-a61f-030fd5328d19

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