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Cell studies on Electrohydrodynamic (EHD)-3D-bioprinted Bacterial Cellulose\Polycaprolactone scaffolds for tissue engineering

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Date

2019

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ELSEVIER SCIENCE BV

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Abstract

The application of three-dimensional (3D) printed scaffolds for tissue engineering have gained significant attention in recent years. The biological activity of scaffolds used in tissue engineering applications depends on fabricating high-resolution patterns with fiber orientation and scale. In this study, Bacterial Cellulose (BC) and Polycaprolactone (PCL) composite scaffolds with the line spacing of 100 mu m are produced using Electrohydrodynamic (EHD)-3D-bioprinting technique. The composite scaffolds exhibit enhanced biocompatibility with facilitated cell attachment and proliferation in vitro. The results of this work have demonstrated that EHD-3D-bioprinting method shows great potential for the preparation of BC/PCL composite scaffold and patterns for tissue engineering with enhanced bioactivity. (C) 2018 Published by Elsevier B.V.

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Keywords

EHD-3D-bioprinting, Biomaterials, Polymers, Bacterial Cellulose, Polycaprolactone, IN-VITRO, 3D

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