Publication:
The effect of polycaprolactone/graphene oxide electrospun scaffolds on the neurogenic behavior of adipose stem cells

Simple item page
dc.contributor.authorPINAR, ERTUĞRUL
dc.contributor.authorÜNAL YILDIRIM, SEMRA
dc.contributor.authorGÜNDÜZ, OĞUZHAN
dc.contributor.authorHARMAN, FERHAT
dc.contributor.authorsPınar E., Şahin A., Ünal Yıldırım S., Gündüz O., Harman F., Kaptanoğlu E.
dc.date.accessioned2022-12-15T08:31:35Z
dc.date.available2022-12-15T08:31:35Z
dc.date.issued2022-02-01
dc.description.abstractStem cell destiny can be controlled with scaffold biomaterials in tissue engineering and regenerative medicine. This study aimed to investigate the neuronal differentiation potential of human adipose tissue-derived mesen- chymal stem cells in graphene nanofiber matrix in vitro. Stem cell isolation was performed from adipose tissue taken from human by mechanical and enzymatic methods. The differentiation potential was examined after incubation of adipose stem cells in normal medium and neural differentiation medium, on graphene oxide (GO) and polycaprolactone (PCL) composite scaffolds produced by electrospinning technique. In vitro studies indi- cated that the presence of GO in PCL scaffold increases an effect on cell attachment, proliferation, infiltration into the scaffold, and neuronal differentiation. Also, unlike subcutaneous tissue, it has been shown immunohis- tochemically that mesenchymal stem cells derived from epidural adipose tissue tend to differentiate into oligodendrocytes.
dc.identifier.citationPınar E., Şahin A., Ünal Yıldırım S., Gündüz O., Harman F., Kaptanoğlu E., "The effect of polycaprolactone/graphene oxide electrospun scaffolds on the neurogenic behavior of adipose stem cells", EUROPEAN POLYMER JOURNAL, cilt.165, ss.0-1, 2022
dc.identifier.endpage1
dc.identifier.issn0014-3057
dc.identifier.urihttps://hdl.handle.net/11424/283646
dc.identifier.volume165
dc.language.isoeng
dc.relation.ispartofEUROPEAN POLYMER JOURNAL
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectSağlık Bilimleri
dc.subjectHealth Sciences
dc.subjectKlinik Tıp (MED)
dc.subjectClinical Medicine (MED)
dc.titleThe effect of polycaprolactone/graphene oxide electrospun scaffolds on the neurogenic behavior of adipose stem cells
dc.typearticle
dspace.entity.typePublication
local.avesis.id324ddd66-02da-42e2-b189-79efa10f4752
relation.isAuthorOfPublication804193c2-80e3-48c8-b0f6-f8e125bd801e
relation.isAuthorOfPublication58e004a6-536f-4997-ac76-8f097aaa1cea
relation.isAuthorOfPublicationf11e8073-bf2f-485f-9bdf-5b3a2a0bdc1f
relation.isAuthorOfPublication636ea873-3c09-4805-a364-a23e5f76568d
relation.isAuthorOfPublication.latestForDiscovery804193c2-80e3-48c8-b0f6-f8e125bd801e

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
6.pdf
Size:
10.23 MB
Format:
Adobe Portable Document Format
Download

Collections

Research Outputs