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Evaluation of therapeutics management patterns and glycemic control of pediatric type 1 diabetes mellitus patients in Turkey: A nationwide cross-sectional study

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dc.contributor.authorBEREKET, ABDULLAH
dc.contributor.authorsHatun, Sukru; Demirbilek, Huseyin; Darcan, Sukran; Yuksel, Aysegul; Binay, Cigdem; Simsek, Damla Goksen; Kara, Cengiz; Cetinkaya, Ergun; Unuvar, Tolga; Ucakturk, Ahmet; Tutunculer, Filiz; Cesur, Yasar; Bundak, Ruveyde; Saglam, Halil; Simsek, Enver; Bereket, Abdullah
dc.date.accessioned2022-03-12T20:30:22Z
dc.date.available2022-03-12T20:30:22Z
dc.date.issued2016
dc.description.abstractAims: To evaluate the management strategies, glycemic control and complications of pediatric type 1 diabetes mellitus (T1DM) patients in Turkey. Methods: Study included 498 patients with T1DM between the ages 1-18. Data provided from patients' hospital files were recorded on standard case report forms by applicant clinicians within the 3 months of data collection period between October 2012 and July 2013. Results: Mean age of patients was 11.3 +/- 3.8 years. Mean duration of DM was determined as 3.7 +/- 3.1 years. Majority of patients (85.5%) used basal/bolus injection (BBI), and 6.5% used continuous subcutaneous insulin infusion pump. Assessment of glycemic control based on HbA1c levels showed that 29.1% of patients had an HbA1c value <7.5% (58 mmol/mol), 16.1% had a value between 7.5% (58 mmol/mol) and 8% (64 mmol/mol), 19.1% had a value between 8.1% (64 mmol/mol) and 9%(75 mmol/mol) and 35.7% a value >9%(75 mmol/mol). Hypoglycemia was reported in 145 (29.1%) patients and the number of severe hypoglycemic attacks in the last 3 months was 1.0 +/- 2.4. Taking into consideration the carbohydrate count and insulin correction dose and parents with high socioeconomic status was related to have better glycemic control. The most common comorbidities were Hashimoto's thyroiditis/hypothyroidism (6.2%) followed by celiac disease (3.8%), epilepsy(1.2%), and asthma(1.0%). Conclusions: BBI insulin therapy is widely used among pediatric T1DM patients in Turkey. However, despite improvements in treatment facilities and diabetic care, glycemic control is not at a satisfactory level. Therefore, new and comprehensive initiatives require for pediatric T1DM patients with poor glycemic control. Promoting use of carbohydrate count and insulin correction doses may improve the glycemic control of pediatric T1DM in Turkey. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
dc.identifier.doi10.1016/j.diabres.2016.04.059
dc.identifier.eissn1872-8227
dc.identifier.issn0168-8227
dc.identifier.pubmed27423071
dc.identifier.urihttps://hdl.handle.net/11424/234168
dc.identifier.wosWOS:000381646900004
dc.language.isoeng
dc.publisherELSEVIER IRELAND LTD
dc.relation.ispartofDIABETES RESEARCH AND CLINICAL PRACTICE
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectType 1 diabetes
dc.subjectChildren
dc.subjectTreatment
dc.subjectGlycemic control
dc.subjectHbA1c
dc.subjectCHILDREN
dc.subjectASSOCIATION
dc.subjectPREVALENCE
dc.subjectREGION
dc.subjectRISK
dc.titleEvaluation of therapeutics management patterns and glycemic control of pediatric type 1 diabetes mellitus patients in Turkey: A nationwide cross-sectional study
dc.typearticle
dspace.entity.typePublication
local.avesis.id7728cf7c-d827-4923-bfee-c31e84a3f86c
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages9
local.journal.quartileQ2
oaire.citation.endPage40
oaire.citation.startPage32
oaire.citation.titleDIABETES RESEARCH AND CLINICAL PRACTICE
oaire.citation.volume119
relation.isAuthorOfPublication669e9474-4e39-453f-a4bc-4ede9cb5abac
relation.isAuthorOfPublication.latestForDiscovery669e9474-4e39-453f-a4bc-4ede9cb5abac

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