Publication:
EVALUATION OF ANTIOXIDANT, RADICAL-SCAVENGING AND ACETYLCHOLINESTERASE INHIBITORY ACTIVITIES OF VARIOUS CULINARY HERBS CULTIVATED IN SOUTHERN TURKEY

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dc.contributor.authorOGAN, AYŞE
dc.contributor.authorsDanis, Ozkan; Yuce-Dursun, Basak; Cimen, Talin; Demir, Serap; Salan, Umit; Yalcin, Guler; Ogan, Ayse
dc.date.accessioned2022-03-13T12:44:47Z
dc.date.available2022-03-13T12:44:47Z
dc.date.issued2014
dc.description.abstractThe purpose of this study was to determine the antioxidant, radical-scavenging, and acetylcholinesterase inhibitory capabilities of water and methanol extracts of Rhus coriariaL., Ocimum basilicumL., Rosmarinus officinalisL., Salvia officinalisL. and Thymbra spicataL., which are grown in the Hatay province of Turkey. Total antioxidant activities were evaluated using 2,2-diphenyl-1-picrylhydrazyl (22-782.6g/mL EC50),OH scavenging (3.93-33.43g/mL EC50), ferric (0.143-3.083mmol trolox equivalent (TE)/g), and cupric-reducing antioxidant power (0.143-3.083mmol TE/g) assays. The phenolic composition of the methanolic extract of R.coriaria leaves was also investigated, and the active compound was identified as 4-O-methylgallic acid. The highest IC50 value of acetylcholinesterase inhibitory activity (1.170.04mg/mL) was observed in R.coriaria leaves. Principal component analysis showed that R.coriaria leaves possessed greater antioxidant and anti-acetylcholinesterase potential as compared with the other evaluated plants. Practical ApplicationsAntioxidants are widely used in the food industry to prevent the formation of toxic oxidation products and prolong shelf life. Because of increasing concern among consumers about the use of synthetic antioxidants, there has been a great interest in the identification and use of natural antioxidants. The present study reveals that Rhus coriaria leaves, which are not commonly used in Mediterranean cuisine, are a promising source of natural antioxidants and could be considered as a potential source of anti-acetylcholinesterase agents and food preservatives. Both the antioxidant and anti-acetylcholinesterase effects of R.coriaria leaves may be beneficial in the treatment of Alzheimer's disease.
dc.identifier.doi10.1111/jfbc.12095
dc.identifier.eissn1745-4514
dc.identifier.issn0145-8884
dc.identifier.urihttps://hdl.handle.net/11424/237647
dc.identifier.wosWOS:000346589200008
dc.language.isoeng
dc.publisherWILEY
dc.relation.ispartofJOURNAL OF FOOD BIOCHEMISTRY
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectOFFICINALIS L.
dc.subjectCAPACITY
dc.subjectEXTRACTS
dc.subjectLEAVES
dc.subjectACID
dc.titleEVALUATION OF ANTIOXIDANT, RADICAL-SCAVENGING AND ACETYLCHOLINESTERASE INHIBITORY ACTIVITIES OF VARIOUS CULINARY HERBS CULTIVATED IN SOUTHERN TURKEY
dc.typearticle
dspace.entity.typePublication
local.avesis.id3154ab05-bd57-4244-9ece-2bd4333be466
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.journal.numberofpages10
oaire.citation.endPage611
oaire.citation.issue6
oaire.citation.startPage602
oaire.citation.titleJOURNAL OF FOOD BIOCHEMISTRY
oaire.citation.volume38
relation.isAuthorOfPublication58db3332-a5f8-4224-a021-aeea795f52fa
relation.isAuthorOfPublication.latestForDiscovery58db3332-a5f8-4224-a021-aeea795f52fa

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