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Evaluation of new treatments for benign prostatic obstruction: ICI-RS 2023

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dc.contributor.authorTARCAN, TUFAN
dc.contributor.authorsHashim H., Tarcan T., Acar O., Malde S., Wein A., Abrams P.
dc.date.accessioned2023-12-13T06:18:41Z
dc.date.available2023-12-13T06:18:41Z
dc.date.issued2023-12-11
dc.description.abstractAims: To address how invasive therapies for benign prostatic obstruction (BPO) have been evaluated, what their effect is on BPO, if they can prevent progression to BPO and how new therapies need to be evaluated before implementation into clinical practice. Methods: The think tank conducted a literature review and looked at the previous and current American Urological Association, European Association of Urology and the International Consultation on Urological Diseases guidelines to see what procedures have been used to treat BPO. They then assessed whether trials have been conducted before implementation of the procedures and whether they have been compared to a “gold” standard treatment. The use of urodynamics has also been addressed in the think tank in relation the clinical trials as well as terminology. Results: Guidelines vary in the use of terminology when it comes to BPO with some continuing to use the term benign prostatic hyperplasia (BPH). There are several procedures for example, TUNA, which have become obsolete although continues to be mentioned in the guidelines until recently. Majority of procedures have been introduced without comparing to “gold” standard treatment and without any long‐term data. There continues to be many unknowns with regard to the success of some of the BPO procedures and why some of the adverse events develop. Conclusion: There needs to be more robust long‐term clinical trials conducted of new BPO therapies, with men who have both lower urinary tract symptoms and urinary retention, before introduction into clinical practice.
dc.identifier.citationHashim H., Tarcan T., Acar O., Malde S., Wein A., Abrams P., "Evaluation of new treatments for benign prostatic obstruction: ICI-RS 2023.", Neurourology and urodynamics, 2023
dc.identifier.doi10.1002/nau.25345
dc.identifier.issn0733-2467
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/epdf/10.1002/nau.25345
dc.identifier.urihttps://hdl.handle.net/11424/295589
dc.language.isoeng
dc.relation.ispartofNeurourology and urodynamics
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectbenign prostatic hyperplasia
dc.subjectbenign prostatic obstruction
dc.subjectHoLEP
dc.subjectTURP
dc.subjecturodynamics
dc.titleEvaluation of new treatments for benign prostatic obstruction: ICI-RS 2023
dc.typearticle
dspace.entity.typePublication
local.avesis.id74df50de-c8ab-4979-8825-30ca63112fc1
local.indexed.atPUBMED
relation.isAuthorOfPublication879ebbce-00dd-443f-a277-a62048cfd68c
relation.isAuthorOfPublication.latestForDiscovery879ebbce-00dd-443f-a277-a62048cfd68c

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