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Comparative Studies on Essential Oil and Phenolic Content with In Vitro Antioxidant, Anticholinesterase, Antimicrobial Activities of Achillea biebersteinii Afan. and A. millefolium subsp. millefolium Afan. L. Growing in Eastern Turkey

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dc.contributor.authorTAŞKIN, TURGUT
dc.contributor.authorsToplan G. G., TAŞKIN T., İŞCAN G., GÖGER F., KÜRKÇÜOĞLU M., Civas A., Ecevit-Genc G., Mat A., Baser K. H. C.
dc.date.accessioned2023-04-10T07:21:53Z
dc.date.available2023-04-10T07:21:53Z
dc.date.issued2022-03-01
dc.description.abstractThe potential applications of Achillea species in various industries have encouraged the examination of their phytochemical components along with their biological potential. In the present study, phenolic contents and essential oil compositions together with the in vitro biological activities of the aerial parts from Achillea biebersteinii Afan. and Achillea millefolium subsp. millefolium Afan. collected from Turkey were evaluated. Different solvent extracts (n-hexane, chloroform, methanol, water) were prepared and their antimicrobial, anticholinesterase, and antioxidant activities were studied. The LC-MS/MS results revealed the presence of 16 different phenolic compounds, including chlorogenic acid, rutin, quercetin, and luteolin glycosides, in methanolic extracts. According to GC-FID and GC/MS results, the primary components of the oils were identified as 1,8-cineole (32.5%), piperitone (14.4%), and camphor (13.7%) in A. biebersteinii and 1,8-cineole (12.3%) and beta-eudesmol (8.9%) in A. millefolium subsp. millefolium. The infusion and methanolic extracts of both species were found to be rich in their total phenolic content as well as their antioxidant and anticholinesterase activity. In contrast, the n-hexane and chloroform extracts of both species showed strong antimicrobial activity with MIC values ranging from 15 to 2000 mu g/mL. Our findings suggest that the investigated Achillea species could be evaluated as potent natural agents, and further studies into the promising extracts are needed.
dc.identifier.citationToplan G. G., TAŞKIN T., İŞCAN G., GÖGER F., KÜRKÇÜOĞLU M., Civas A., Ecevit-Genc G., Mat A., Baser K. H. C., "Comparative Studies on Essential Oil and Phenolic Content with In Vitro Antioxidant, Anticholinesterase, Antimicrobial Activities of Achillea biebersteinii Afan. and A. millefolium subsp. millefolium Afan. L. Growing in Eastern Turkey", MOLECULES, cilt.27, sa.6, 2022
dc.identifier.doi10.3390/molecules27061956
dc.identifier.issn1420-3049
dc.identifier.issue6
dc.identifier.urihttps://avesis.marmara.edu.tr/api/publication/ec557d80-a2fa-4cde-94ac-07403cfdc4ca/file
dc.identifier.urihttps://hdl.handle.net/11424/288501
dc.identifier.volume27
dc.language.isoeng
dc.relation.ispartofMOLECULES
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectYaşam Bilimleri
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectSitogenetik
dc.subjectKimya
dc.subjectBiyokimya
dc.subjectAlkoloidler
dc.subjectTemel Bilimler
dc.subjectLife Sciences
dc.subjectMolecular Biology and Genetics
dc.subjectCytogenetic
dc.subjectChemistry
dc.subjectBiochemistry
dc.subjectAlcaloides
dc.subjectNatural Sciences
dc.subjectBİYOKİMYA VE MOLEKÜLER BİYOLOJİ
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectKİMYA, MULTİDİSİPLİNER
dc.subjectTemel Bilimler (SCI)
dc.subjectBIOCHEMISTRY & MOLECULAR BIOLOGY
dc.subjectMOLECULAR BIOLOGY & GENETICS
dc.subjectLife Sciences (LIFE)
dc.subjectCHEMISTRY, MULTIDISCIPLINARY
dc.subjectCHEMISTRY
dc.subjectNatural Sciences (SCI)
dc.subjectBiochemistry, Genetics and Molecular Biology (miscellaneous)
dc.subjectClinical Biochemistry
dc.subjectCancer Research
dc.subjectMolecular Biology
dc.subjectDrug Discovery
dc.subjectAging
dc.subjectGeneral Biochemistry, Genetics and Molecular Biology
dc.subjectStructural Biology
dc.subjectChemistry (miscellaneous)
dc.subjectGeneral Chemistry
dc.subjectPhysical Sciences
dc.subjectAchillea biebersteinii
dc.subjectAchillea millefolium subsp
dc.subjectmillefolium
dc.subjectLC-MS
dc.subjectMS
dc.subjectessential oil
dc.subjectGC-GC
dc.subjectantimicrobial
dc.subjectantioxidant
dc.subjectanticholinesterase
dc.subjectCHEMICAL-COMPOSITION
dc.subjectBIOLOGICAL-ACTIVITIES
dc.subjectPHYTOCHEMICAL ANALYSIS
dc.subjectVOLATILE CONSTITUENTS
dc.subjectEXTRACT
dc.subjectNOBILIS
dc.subjectYARROW
dc.subjectWILD
dc.subjectS.L.
dc.subjectAchillea biebersteinii
dc.subjectAchillea millefolium subsp. millefolium
dc.subjectLC-MS/MS
dc.subjectessential oil
dc.subjectGC-GC/MS
dc.subjectantimicrobial
dc.subjectantioxidant
dc.subjectanticholinesterase
dc.titleComparative Studies on Essential Oil and Phenolic Content with In Vitro Antioxidant, Anticholinesterase, Antimicrobial Activities of Achillea biebersteinii Afan. and A. millefolium subsp. millefolium Afan. L. Growing in Eastern Turkey
dc.typearticle
dspace.entity.typePublication
local.avesis.idec557d80-a2fa-4cde-94ac-07403cfdc4ca
local.indexed.atWOS
local.indexed.atPUBMED
local.indexed.atSCOPUS
relation.isAuthorOfPublication265414e9-485c-42b8-903a-c467f6b49b84
relation.isAuthorOfPublication.latestForDiscovery265414e9-485c-42b8-903a-c467f6b49b84

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