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Effects of multiple pulmonary aspirations of enteral solutions on lung tissue damage

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dc.contributor.authorYILDIZELİ, BEDRETTİN
dc.contributor.authorsUmuroglu, T; Takil, A; Irmak, P; Yildizeli, B; Ahiskali, R; Dogan, V; Gogus, FY
dc.date.accessioned2022-03-12T17:19:24Z
dc.date.available2022-03-12T17:19:24Z
dc.date.issued2006
dc.description.abstractBackground Et aim: The aim of this study was to compare the pulmonary histopathologic effects of enteral solutions with various lipid content, after multiple aspirations in rats. Methods: Thirty Wistar albino rats were randomly assigned to one of three groups (n = 10). Salinesolution (0.9%) (group C, control), Impact (lipid content, 28g/l; group I), Pulmocare (lipid content, 93.3g/l; group P) were injected into the lung through the trachea, in a volume of 0.8 ml/kg. The aspiration procedure was performed three times in total, in every 2 days. After seven days from the first aspiration, rats were killed, and lungs were examined for histopathologic examination. Results: Alveolar histiocytes were statistically higher in left lungs of the group I than the left ones of the control group(P < 0.05). Lipid-laden alveolar macrophages were significantly higher in left lungs of groups I and, P than left lungs of the control group (P < 0.05). Conclusion: Lung tissue damage occuring after multiple pulmonary aspirations of Impact and Pulmocare, is histopathotogically similar to each other, and is in the form of lipoid pneumonia. In cases of multiple pulmonary aspirations, volume of the aspirate and chronicicity of the aspiration took like major impact factors rather than the amount of the lipid. (c) 2005 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.
dc.identifier.doi10.1016/j.clnu.2005.08.011
dc.identifier.eissn1532-1983
dc.identifier.issn0261-5614
dc.identifier.pubmed16219392
dc.identifier.urihttps://hdl.handle.net/11424/228102
dc.identifier.wosWOS:000236436000004
dc.language.isoeng
dc.publisherCHURCHILL LIVINGSTONE
dc.relation.ispartofCLINICAL NUTRITION
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectacute lung injury
dc.subjectenteral formulas
dc.subjectlipoid pneumonia
dc.subjectLIPOID PNEUMONIA
dc.subjectCHILDREN
dc.subjectFEEDINGS
dc.subjectGUT
dc.titleEffects of multiple pulmonary aspirations of enteral solutions on lung tissue damage
dc.typearticle
dspace.entity.typePublication
local.avesis.idb9f7753c-6ee0-49ca-ab1f-c2f2610ea807
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages6
oaire.citation.endPage50
oaire.citation.issue1
oaire.citation.startPage45
oaire.citation.titleCLINICAL NUTRITION
oaire.citation.volume25
relation.isAuthorOfPublicationd6b68c67-eea7-4dc3-8688-e8cfbe3bbcd2
relation.isAuthorOfPublication.latestForDiscoveryd6b68c67-eea7-4dc3-8688-e8cfbe3bbcd2

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